Treatment of Cerebral Venous Thrombosis in a Child with Warfarin Based on Gene Polymorphism

Luo Ping; Zhang Hui; He Weiwen; Qu Qiang

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Treatment of Cerebral Venous Thrombosis in a Child with Warfarin Based on Gene Polymorphism

更新时间：2022-11-04

- Treatment of Cerebral Venous Thrombosis in a Child with Warfarin Based on Gene Polymorphism
- Vol. 28, Issue 8, Pages: 13-16(2022)
- 作者机构：
  
  中南大学湘雅医院,湖南,长沙,410008
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：2022，
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Luo Ping, Zhang Hui, He Weiwen, et al. Treatment of Cerebral Venous Thrombosis in a Child with Warfarin Based on Gene Polymorphism. [J]. 28(8):13-16(2022)
DOI：

Luo Ping, Zhang Hui, He Weiwen, et al. Treatment of Cerebral Venous Thrombosis in a Child with Warfarin Based on Gene Polymorphism. [J]. 28(8):13-16(2022) DOI：

摘要

目的：探讨临床药师在儿童脑静脉窦血栓形成治疗中的药学监护作用，为临床合理用药提供参考。方法：回顾性分析临床药师对1例儿童脑静脉窦血栓形成治疗中的药学监护过程。结果：临床药师通过分析患儿病情、华法林基因型和国际标准化比值，协助临床医师调整华法林用药方案，患儿康复出院。结论：临床药师基于基因多态性参与患儿华法林个体化抗凝方案的制定，有利于提高药物治疗水平，确保患儿用药安全、有效。

Abstract

Objective: To probe into the role of clinical pharmacists in pharmaceutical care for the treatment of a child with cerebral venous thrombosis

so as to provide reference for the rational clinical drug use. Methods: Retrospective analysis was performed on the pharmaceutical care for a child with cerebral venous thrombosis by clinical pharmacists. Results: By analyzing the disease condition

genotype of warfarin and international normalized ratio of the child

the clinical pharmacists assisted the clinicians to adjust the dose of warfarin. The child recovered and was discharged from the hospital. Conclusion: Based on genetic polymorphism

clinical pharmacists participate into the formulation of anticoagulation regimens for children with warfarin

which promote the rational clinical drug use

and further ensure the safety of drug use in children.

关键词

儿童脑静脉窦血栓华法林药学监护

Keywords

childrencerebral venous thrombosiswarfarinpharmaceutical care

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