Risk factors for postoperative bleeding after submucosal tunneling endoscopic resection of gastric stromal tumor

LI Yun; LIU Chao; LIU Lin; XIA Xiuli; XU Chao; YAN Lingxin

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Risk factors for postoperative bleeding after submucosal tunneling endoscopic resection of gastric stromal tumor

更新时间：2022-06-24

- Risk factors for postoperative bleeding after submucosal tunneling endoscopic resection of gastric stromal tumor
- null Issue 6, Pages: 502(2021)
- 作者机构：
  
  1. 邯郸市中心医院消化内科一病区,河北,邯郸,056001
  2. 邯郸市中心医院消化内科二病区,河北,邯郸,056001
- 作者简介：
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LI Yun, LIU Chao, LIU Lin, et al. Risk factors for postoperative bleeding after submucosal tunneling endoscopic resection of gastric stromal tumor. [J]. null (6):502(2021)
DOI：

LI Yun, LIU Chao, LIU Lin, et al. Risk factors for postoperative bleeding after submucosal tunneling endoscopic resection of gastric stromal tumor. [J]. null (6):502(2021) DOI：

摘要

目的分析经黏膜下隧道内镜肿瘤切除术（STER）治疗胃间质瘤的临床疗效及影响术后出血的危险因素。方法选择行STER治疗的251例胃间质瘤患者作为研究对象，分析STER的临床治疗效果及术后迟发性出血的发生情况。依据STER术后有无出血将患者分为出血组和未出血组，并采用单因素及多因素Logistic回归分析胃间质瘤STER术后出血的危险因素。结果 251例胃间质瘤患者〖JP〗均顺利完成STER，整块切除率达100%（251/251），未见肿瘤残留，随访1年未发现远处转移、新发肿瘤或死亡病例；术后病理结果显示239例（95.2%）CD117阳性，241例（96.0%）DOG-1阳性，134例（53.4%）CD34阳性，16例（6.4%）S-100蛋白阳性；术后12 h~14 d发生创面出血的患者有27例（10.8%）。单因素分析显示年龄、病变部位、瘤体最大径、术中明显出血、手术者操作熟练程度是与STER术后出血有关的危险因素；多因素Logistic回归分析结果显示，病变部位为贲门—胃底、瘤体最大径≥4 cm、手术者操作不熟练是STER术后出血的独立危险因素。结论 STER治疗胃间质瘤效果理想，但术后出血的发生率较高，影响STER术后出血的危险因素包括病变部位、瘤体最大径、手术者操作熟练程度等。

Abstract

关键词

内镜经黏膜下隧道内镜肿瘤切除术胃间质瘤术后出血危险因素

Keywords

endoscopysubmucosal tunneling endoscopic resectiongastric stromal tumorpostoperative bleedingrisk factors

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