Effect of dexmedetomidine combined with ropivacaine sacral block on postoperative analgesia and chronic pain in children with hypospadias

SUN Weiguo; ZHOU Liping; WANG Haiyan; HU Zurong; YANG Shihui

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Effect of dexmedetomidine combined with ropivacaine sacral block on postoperative analgesia and chronic pain in children with hypospadias

更新时间：2022-06-24

- Effect of dexmedetomidine combined with ropivacaine sacral block on postoperative analgesia and chronic pain in children with hypospadias
- null Issue 6, Pages: 511(2021)
- 作者机构：
  
  1. 广东省妇幼保健院麻醉科,广东,广州,511442
  2. 广东省妇幼保健院产科,广东,广州,511442
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SUN Weiguo, ZHOU Liping, WANG Haiyan, et al. Effect of dexmedetomidine combined with ropivacaine sacral block on postoperative analgesia and chronic pain in children with hypospadias. [J]. null (6):511(2021)
DOI：

SUN Weiguo, ZHOU Liping, WANG Haiyan, et al. Effect of dexmedetomidine combined with ropivacaine sacral block on postoperative analgesia and chronic pain in children with hypospadias. [J]. null (6):511(2021) DOI：

摘要

目的探讨超声引导下右美托咪定复合罗哌卡因骶管阻滞对小儿尿道下裂修复术后镇痛和慢性疼痛的影响。方法选取行择期尿道下裂修复术患儿90例

随机分为罗哌卡因组(R组)和罗哌卡因+右美托咪定组(R+D组)

每组45例。R组注射0.15%罗哌卡因1 mL/kg

R+D组注射0.15%罗哌卡因+右美托咪定1 μg/kg。统计2组患儿麻醉时间、手术时间、住院时间、生命体征、小儿FLACC评分、Ramsay镇静(RSS)评分、不良反应发生率、膀胱痉挛发生率、有效镇痛时间和辅助用药剂量。记录2组患儿出院后1个月、2个月、3个月的FLACC评分。结果 2组患儿手术时间、麻醉时间比较，差异无统计学意义(P>0.05)；R+D组住院时间较R组短(P<0.05)。术后4 h、8 h、16 h，2组心率比较差异无统计学意义(P>0.05)；术后24～72 h，R+D组心率较R组慢(P<0.05）。术后4 h，2组平均动脉压比较差异无统计学意义(P>0.05)；术后8～72 h，R+D组平均动脉压较R组低(P<0.05)。术后4 h、8 h，2组FLACC评分比较差异无统计学意义(P>0.05)；术后16 h、24 h、36 h、48 h、72 h，R+D组FLACC评分低于R组(P<0.05)。术后4 h、8 h、36 h、48 h、72 h，2组RSS评分比较差异均有统计学意义(P<0.05)；术后16 h、24 h，2组RSS评分比较差异无统计学意义(P>0.05)。R+D组有效镇痛时间长于R组(P<0.05)，布洛芬悬液和曲马多注射液用量均少于R组(P<0.05)，2组恶心呕吐发生率比较差异无统计学意义(P＞0.05)，R+D组膀胱痉挛发生率低于R组(P<0.05)。出院后1个月，R+D组FLACC评分低于R组(P<0.05)；出院后2个月、3个月，2组FLACC评分比较差异无统计学意义(P>0.05)。结论右美托咪定复合罗哌卡因骶管阻滞联合术后静脉镇痛

可延长有效镇痛时间

缩短住院时间，且镇痛期间不良反应少

术后3个月内患者均未见慢性疼痛的发生。

Abstract

关键词

超声引导右美托咪定罗哌卡因骶管阻滞尿道下裂慢性疼痛

Keywords

ultrasound guidancedexmedetomidineropivacainesacral blockhypospadiaschronic pain

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