Expression and clinical significance of IFITM1 in liver cancer tissues

WU An-meng; MA Zhi-jian; ZHANG Wei; YUAN Jing; LUO Liang; MI Riguli; ZHENG Wei-nan

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Expression and clinical significance of IFITM1 in liver cancer tissues

更新时间：2022-06-24

- Expression and clinical significance of IFITM1 in liver cancer tissues
- null Issue 4, Pages: 315(2022)
- 作者机构：
  
  1. 成都医学院公共卫生学院预防医学系,四川,成都,610500
  2. 海南医学院人体解剖学教研室,海南,海口,571199
  3. 成都医学院基础医学院人体解剖学与组织胚胎学教研室/发育与再生四川省重点实验室,四川,成都,610500
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WU An-meng, MA Zhi-jian, ZHANG Wei, et al. Expression and clinical significance of IFITM1 in liver cancer tissues. [J]. null (4):315(2022)
DOI：

WU An-meng, MA Zhi-jian, ZHANG Wei, et al. Expression and clinical significance of IFITM1 in liver cancer tissues. [J]. null (4):315(2022) DOI：

摘要

目的探讨肝癌组织中干扰素诱导的跨膜蛋白1（IFITM1）的表达及其在病理分级中的意义。方法采用免疫组织化学法检测IFITM1在肝癌组织中的表达并分析其与病理分级的关系。结果 IFITM1在肝癌组织中的表达低于正常肝组织，差异有显著统计学意义（P<0.01）；肝癌组织病理分级与IFITM1表达呈正相关，肝癌组织的分化程度越高，IFITM1表达水平越高，肝癌的恶性程度越低；而肝癌组织的分化程度越低，IFITM1表达水平越低，肝癌的恶性程度越高，差异有显著统计学意义（P<0.01）。结论 IFITM1在肝癌组织中低表达，不同病理分级中IFITM1的表达不同，可能与肝癌的发生有关。

Abstract

关键词

肝癌IFITM1病理分级免疫组织化学

Keywords

liver cancerIFITM1pathological gradeimmunohistochemistry

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