Clinical observation of Yuanhu Zhitong tablets combined with strong opioids in treatment of patients with moderate to severe pain after lung cancer surgery

TAN Dan; ZENG Xiaoqin; BAO Quanwei; CHEN Jian

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Clinical observation of Yuanhu Zhitong tablets combined with strong opioids in treatment of patients with moderate to severe pain after lung cancer surgery

更新时间：2022-06-24

- Clinical observation of Yuanhu Zhitong tablets combined with strong opioids in treatment of patients with moderate to severe pain after lung cancer surgery
- null Issue 1, Pages: 55(2020)
- 作者机构：
  
  1. 陆军军医大学第二附属医院急诊部,重庆,400037
  2. 陆军军医大学第二附属医院呼吸与危重症医学科,重庆,400037
  3. 陆军军医大学全军免疫学研究所,重庆,400037
- 作者简介：
- 基金信息：
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TAN Dan, ZENG Xiaoqin, BAO Quanwei, et al. Clinical observation of Yuanhu Zhitong tablets combined with strong opioids in treatment of patients with moderate to severe pain after lung cancer surgery. [J]. null (1):55(2020)
DOI：

TAN Dan, ZENG Xiaoqin, BAO Quanwei, et al. Clinical observation of Yuanhu Zhitong tablets combined with strong opioids in treatment of patients with moderate to severe pain after lung cancer surgery. [J]. null (1):55(2020) DOI：

摘要

目的观察元胡止痛片联合强阿片类药物治疗肺癌术后中重度疼痛的临床疗效。方法选取2015年1月至2017年12月在我院接受肺癌手术并采用数字评估量表（NRS）法评估疼痛程度为中重度的患者100例，将其随机分为对照组和治疗组。对照组口服给予盐酸羟考酮缓释片治疗，治疗组则在口服盐酸羟考酮缓释片的基础上，口服元胡止痛片，观察2组患者的临床疗效。结果 2组镇痛效果相当，差异无统计学意义（P＞0.05）；与对照组相比，治疗组可减少滴定结束时所需要的盐酸羟考酮缓释片的剂量，差异具有统计学意义（P＜0.05）；治疗组的恶心、呕吐及便秘的总发生率和Ⅱ度+Ⅲ度的不良反应总发生率低于对照组，差异有统计学意义（P＜0.05）。结论元胡止痛片联合强阿片类药物在缓解肺癌术后中重度疼痛中镇痛效果显著且不良反应更少。

Abstract

关键词

元胡止痛片盐酸羟考酮缓释片镇痛管理三阶梯原则中重度疼痛肺癌术后疼痛

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