Meta-analysis of risk factors for refracture of adjacent vertebrae after PVP/PKP treatment

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Meta-analysis of risk factors for refracture of adjacent vertebrae after PVP/PKP treatment

更新时间：2022-06-24

- Meta-analysis of risk factors for refracture of adjacent vertebrae after PVP/PKP treatment
- null Issue 10, Pages: 881(2021)
- 作者机构：
  
  1. 衡阳市中心医院/南方医科大学附属衡阳医院骨科,湖南,衡阳,421001
  2. 南方医科大学第二临床医学院,广东,广州,510515
  3. 海口市人民医院/中南大学湘雅医学院附属海口医院骨科,海南,海口,570208
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Meta-analysis of risk factors for refracture of adjacent vertebrae after PVP/PKP treatment. [J]. null (10):881(2021)
DOI：

Meta-analysis of risk factors for refracture of adjacent vertebrae after PVP/PKP treatment. [J]. null (10):881(2021) DOI：

摘要

目的通过Meta分析探讨经皮椎体成形术（PVP）/经皮椎体后凸成形术（PKP）后邻椎再骨折的危险因素。方法计算机检索中国生物医学文献数据库、中国知网、万方、维普、PubMed、Web of Science、Embase等中英文数据库，检索词主要包括“骨水泥成形术”“椎体成形术”“再骨折”“vertebroplasty”“kyphoplasty”“refracture”等，根据纳入及排除标准筛选文献后，使用NOS严格评价文献质量，提取相关数据后使用RevMan 5.3软件进行统计分析。结果最终共纳入19篇文献，均为病例对照研究，研究对象共3 678例，其中病例组523例，对照组3 155例；通过Meta分析认为PVP/PKP后邻椎再骨折的危险因素包括骨密度较低［OR=5.57（95% CI:4.08

7.59）］、术前椎体陈旧性骨折数量过多（≥2）［OR=2.38（95% CI:1.14

4.96）］、椎体骨折数量过多（≥2）［OR=5.78（95% CI:4.30

7.76）］、术后未行抗骨质疏松治疗［OR=3.74（95% CI: 1.79

7.80）］、高龄［OR=3.51（95% CI：2.72

4.52）］、低BMI［OR=1.57（95% CI：1.17

2.10）］、骨水泥过量［OR=3.92（95% CI:2.39

6.45）］、手术椎体数量过多（≥2）［OR=5.01（95% CI: 3.08

8.17）］、伤椎高度过度恢复［OR=2.66（95% CI:1.78

3.97）］、术后椎体后凸角过大［OR=3.55（95% CI:2.41

5.22）］、骨水泥渗漏［OR=4.79（95% CI:3.25

7.05）］。结论 PVP/PKP后邻近椎再骨折的危险因素较多，临床上应做好术前评估及术后预防，以避免PVP/PKP后邻椎再骨折发生。

Abstract

关键词

经皮椎体成形术经皮椎体后凸成形术椎体骨质疏松压缩骨折再骨折危险因素Meta分析

Keywords

percutaneous vertebroplastypercutaneous kyphoplastyvertebraeosteoporosiscompression fracturerefracturerisk factorsMetaanalysis

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