Objective:To compare the advantages and disadvantages of three common hepatic vascular casting agents

and to investigate the influence of temperature on the dissolution time and curing time of mixed casting agent.Methods:A total of 18 male rabbits were randomly divided into three groups

with 6 rabbits in each group.The portal vein and the posterior vena cava were perfused with three casting agents

and dissolution time and curing time at different temperatures were compared for the liver cast specimens and the mixed casting agent.Results:The perchloroethylene specimen had few bubbles

high integrity

good distal filling

and good toughness

as well as a long production cycle; the cast specimen of self-curing denture base material had very few bubbles

a short production cycle

good toughness

good integrity

and relatively poor distal filling; the specimen of mixed casting agent had slightly more bubbles

a short production cycle

and good toughness

integrity

and distal filling.The dissolution time and curing time of perchloroethylene-denture base powder mixed casting agent accelerated with the increase in temperature.The Pearson correlation analysis showed that for the mixed casting agent

its dissolution time was negatively correlated with temperature（r =-0.8964

P = 0.0026）and its curing time was also negatively correlated with temperature（r =-0.95346

P = 0.0009）.The dissolution time and curing time of the mixed casting agent decreased with the increase in temperature

with the best casting temperature around 26 ℃.Conclusion:With the mixed casting agent of ethyl acetate and self-curing denture base material

the production of hepatic vascular casting specimens is simple and convenient and has a good casting effect

with 26 °C as the optimal casting temperature.