Objective Analyzing the epidemiological characteristics of hand

foot and mouth disease（HFMD）in Zhuzhou city from 2009 to 2018

the reference basis was provided for scientific and effective measures for prevention and control of HFMD.Methods The data of clinical diagnosis and laboratory diagnosis of HFMD in China′s disease prevention and control information system was used to analyze the epidemiological characteristics of HFMD by describing epidemiological methods.Results From 2009 to 2018

a total of 76 920 cases were reported in the city

and the annual reported incidence was between 47.92/105 to 276.64/105

with an average of 180.63/105.There were 114 serious cases and 16 deaths from 2009 to 2018.The proportion of reported cases of HFMD between men and women is 1.52∶1;The concentration of reported cases among children under the age of 10（76219

99.09%）;The highest incidence was reported in the 1～<2 age group

which reached 4 851.96/105;a total of 47 131 cases were reported from April to July

accounting for 61.27%;the number of reported cases in each district ranged from 16.82/105 to 607.43/105 in each year

the average reported morbidity in the urban areas was higher than that in the counties

and the difference was statistically significant（χ2=28 538.9

P<0.05）;There were 7 258 laboratory-confirmed cases in Zhuzhou city from 2009 to 2018

the overall diagnosis rate was 9.44%

and the proportion of confirmed cases in each year was from 1.49%to 18.79 %.Conclusion The reported incidence of HFMD in Zhuzhou was higher than that of the whole country.The reported incidence of HFMD has obvious seasonality and presents a double peak pattern.The reported incidence of urban areas is significantly higher than that of counties.shows that the prevention and control of HFMD epidemic in Zhuzhou city is relatively severe.