Objective To explore the effects of vitamin D（VD）deficiency on physical and intelligence development of infants in second and third trimester.Methods In a maternal and child health care hospital of Wuhan 90 infants whose mother has VD deficiency in second and third trimester were included in the study group

while 60 infants whose mother has no VD deficiency were selected as control group.The factors of height

head circumference

body mass and speed of skeletal ultrasonils（SOS）of all the infants were examined when they were zero-year old

half a year old and 1-year old.Meanwhile through children′Development Screening Test（DST）the intelligence development of all infants were evaluated when they were zero-year old

half-year old and 1-year old.Results When compared to zero-year old infants

the height

head circumference and body mass of half-year old or 1year-old babies were above

and the difference were significant（P<0.05）.When comparing two groups of infants at the 3time points mentioned above

there was no significant difference between their height

head circumference

body mass and SOS（P>0.05）.The development quotient and mentality index scale of half-year old infants and 1-year old infant were lower than the control group

and the difference was significant（P<0.05）.Infants fall behind in study group were more than control group and the difference was not significant（P<0.05）.Conclusion When women has VD efficiency there was no significant effect on the physical development of infants in the second and third trimester

but it could affect intelligence development.