Developments in the Research of the Treatment of Diabetes with Empagliflozin

ZHANG Yu; YANG Gang-yi

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Developments in the Research of the Treatment of Diabetes with Empagliflozin

更新时间：2021-08-23

- Developments in the Research of the Treatment of Diabetes with Empagliflozin
- Health Medicine Research and Practice Vol. 11, Issue 3, Pages: 90-92(2014)
- 作者机构：
  
  重庆医科大学附属第二医院
- 作者简介：
- 基金信息：
- DOI：
  CLC： R587.1
- Published：2014，
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[1]张瑜,杨刚毅.Empagliflozin治疗糖尿病的研究进展[J].保健医学研究与实践,2014,11(03):90-92.

ZHANG Yu, YANG Gang-yi. Developments in the Research of the Treatment of Diabetes with Empagliflozin. [J]. Health Medicine Research and Practice 11(3):90-92(2014)
[1]张瑜,杨刚毅.Empagliflozin治疗糖尿病的研究进展[J].保健医学研究与实践,2014,11(03):90-92. DOI：

ZHANG Yu, YANG Gang-yi. Developments in the Research of the Treatment of Diabetes with Empagliflozin. [J]. Health Medicine Research and Practice 11(3):90-92(2014) DOI：

摘要

钠葡萄糖协同转运蛋白2（SGLT2）抑制剂是近年来降糖药研究的新热点

其通过抑制肾小管上皮细胞内的主要血糖转运蛋白SGLT2

降低肾小管对葡萄糖的重吸收

从而降低血浆内葡萄糖。临床试验表明新型SGLT2抑制剂Empagliflozin具有良好的降糖效果

能显著降低空腹血糖（FPG）、糖化血红蛋白（HbA1c）

还能显著降低血压和体重

有较好的临床应用前景。

Abstract

Sodium glucose-assisted SGLT2inhibitor is a new hot spot of research on anti-diabetic drugs in recent years.Through suppressing SGLT2

the main blood glucose transporter in the epithelial cells of kidney tubules and hence reducing the re-absorption of glucose by kidney tubules

it serves to lower the amount of glucose inside blood serum.Clinical tests have shown that Empagliflozin

as a new type of SGLT2inhibitor

has a rather good effect on lowering the blood glucose level

and is able to induce a marked decrease of FPG and HbA1c

as well as one’s blood pressure and body weight and is expected to have a bright prospect for clinical application.

关键词

钠-葡萄糖协同转运蛋白2抑制剂2型糖尿病治疗

Keywords

Sodium glucose-assisted SGLT2inhibitorType 2diabetestreatment

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