Objective To observe the clinical therapeutic effect of treating acute suppurative palatal tonsillitis with Potassium Sodium Dehydroandroan and Cefazolin Sodium Pentahydrate.Method To divide 78patients of acute suppurative palatal tonsillitis randomly into experiment group（40）and comparison group（38）.Treatment by Potassium Sodium Dehydroandroan and Cefazolin Sodium Pentahydrate was adopted for the former

and the treatment by Amoxicillin dispersible tablets was adopted for the latter.Results The experiment group had an overall effect rate of 95.0%

while the figure of the comparison group was 52.6%.The difference of the two groups in this regard had statistical significance（P<0.01）.Conclusion The treatment of acute suppurative palatal tonsillitis by Potassium Sodium Dehydroandroan and Cefazolin Sodium Pentahydrate has a marked clinical effectiveness.