An Analysis of Risk Factors of Severe Infectious Mononucleosis

WU Fei; JIANG Li-ping

您当前的位置：

首页 >

文章列表页 >

An Analysis of Risk Factors of Severe Infectious Mononucleosis

更新时间：2021-08-20

- An Analysis of Risk Factors of Severe Infectious Mononucleosis
- Health Medicine Research and Practice Vol. 9, Issue 1, Pages: 10-12(2012)
- 作者机构：
  
  重庆医科大学附属儿童医院
- 作者简介：
- 基金信息：
- DOI：
  CLC： R512.7
- Published：2012，
扫描看全文
[1]吴菲,蒋利萍.重症传染性单核细胞增多症危险因素分析[J].保健医学研究与实践,2012,9(01):10-12.

WU Fei, JIANG Li-ping. An Analysis of Risk Factors of Severe Infectious Mononucleosis. [J]. Health Medicine Research and Practice 9(1):10-12(2012)
[1]吴菲,蒋利萍.重症传染性单核细胞增多症危险因素分析[J].保健医学研究与实践,2012,9(01):10-12. DOI：

WU Fei, JIANG Li-ping. An Analysis of Risk Factors of Severe Infectious Mononucleosis. [J]. Health Medicine Research and Practice 9(1):10-12(2012) DOI：

摘要

目的探讨重症传染性单核细胞增多症（infectious mononucleosis

IM）的临床特点及危险因素。方法回顾性分析346例住院IM患儿的临床资料

对305例普通IM和21例重症IM的病例进行组间对照研究

重症IM发生的危险因素采用Logistic回归分析。结果单因素Logistic回归分析显示

高热（>40℃）、黄疸、血象中2～3系降低、心肌损害、EBV DNA载量大于5.0×106copise/mL与重症IM有关（p<0.05或p<0.01）

对上述5个因素进一步作逐步Logistic回归分析发现

黄疸、EBV DNA载量大于5.0×106copise/mL与重症IM有关（p<0.05或p<0.01）

回归方程Logit（P）=-3.545+1.892x1+3.039x2

方程敏感性57.1%、特异性85.8%。结论 EBV DNA载量大于5.0×106copies/mL和黄疸可能与重症IM发生有关。

Abstract

Objective To explore the clinical characteristics and risk factors of severe infectious mononucleosis（IM）.Method The clinical materials of 346 inpatients with IM received a retrospective analysis.A comparison was made between 305 common cases with IM and 21 cases with severe IM

and the risk factors of severe IM received Logistic regression analysis.Results Single-factor logistic regression analysis indicated that the items including hyperpyrexia（>40℃）

jaundice

the decreases in line two and line three hemogram

cardiac damage and the EBV DNA load（>5.0×106copise/mL） were related to severe IM（p<0.05 or p<0.01）.And the further Logistic regression analysis of these five factors showed that jaundice and the EBV DNA load（>5.0×106copise/mL） were relevant to severe IM（p<0.05 or p<0.01）.The regression equation is Logit（P）=-3.545+1.892x1+3.039x2

and its sensitivity was 57.1% and specificity 85.8%.Conclusion The EBV DNA load（>5.0×106copies/mL） and jaundice may be responsible for the occurrence of severe IM.

关键词

IM重症危险因素

Keywords

IMSevereRisk factors

references

查看原文

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Influencing factors of pregnancy failure in pregnant women with threatened abortion

Characteristics and risk factors analysis of biliary pathogens infection in patients with acute pancreatitis

Analysis of influencing factors and nursing intervention of negative mentality in pregnant women underwent in vitro fertilization-embryo transfer

Analysis of risk facto rs for cerebral microbleeds in patients with ischemic stroke caused by acute small artery occlusion

Analysis of the current situation of hypertension prevalence and influencing factors in Shapingba District,Chongqing

Related Author

Su Yanxia

Chen Luping

Liu Nan

Liu Wenhua

Guo Bin

Zhao Hongyu

Wang Shu

Cheng Luyao

Related Institution

Obstetrics and Gynecology Department, Xiping County People’s Hospital

Department of Clinical Laboratory, Zhenping People’s Hospital

Reproductive Medicine Center, The First Affiliated Hospital of Zhengzhou University

The First Affiliated Hospital of Nanyang Medical College

Center for Disease Control and Prevention,Shapingba District

⁰