团体认知行为干预对高危型HPV持续感染患者临床转归的影响

龙馨; 蒋成刚; 韩容; 朱红锦; 陈彦秋; 杨君

doi:10.16016/j.2097-0927.202307078

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团体认知行为干预对高危型HPV持续感染患者临床转归的影响

临床医学 | 更新时间：2026-01-09

- 团体认知行为干预对高危型HPV持续感染患者临床转归的影响
- Effect of group cognitive behavioral therapy on clinical outcome of patients with persistent high-risk HPV infection
- 陆军军医大学学报 2024年46卷第6期页码：618-622
- 作者机构：
  
  1.401147 重庆，重庆市妇幼保健院(重庆医科大学附属妇女儿童医院)：妇产科
  2.401147 重庆，重庆市妇幼保健院(重庆医科大学附属妇女儿童医院)：睡眠心理科
- 作者简介：
  
  [杨君，E-mail: 850495017@qq.com YANG Jun, E-mail: 850495017@qq.com
- 基金信息：
  
  重庆市妇幼保健院院级科研课题面上项目(2020YJMS04);重庆市妇幼保健院院级科研课题面上项目(2020YJMS05);国家临床重点专科建设项目(妇产科);重庆医科大学未来医学青年创新团队支持计划(W0181);重庆市科卫联合重点基金(2019ZDXM051)
- DOI：10.16016/j.2097-0927.202307078
  中图分类号： R181.32;R373.9;R395.5
- 收稿：2023-07-17，
  
  修回：2023-10-13，
  
  纸质出版：2024-03-30
- 稿件说明：
移动端阅览
龙馨, 蒋成刚, 韩容, 等. 团体认知行为干预对高危型HPV持续感染患者临床转归的影响[J]. 陆军军医大学学报, 2024,46(6):618-622.

Xin LONG, Chenggang JIANG, Rong HAN, et al. Effect of group cognitive behavioral therapy on clinical outcome of patients with persistent high-risk HPV infection[J]. Journal of Army Medical University, 2024, 46(6): 618-622.
龙馨, 蒋成刚, 韩容, 等. 团体认知行为干预对高危型HPV持续感染患者临床转归的影响[J]. 陆军军医大学学报, 2024,46(6):618-622. DOI： 10.16016/j.2097-0927.202307078.

Xin LONG, Chenggang JIANG, Rong HAN, et al. Effect of group cognitive behavioral therapy on clinical outcome of patients with persistent high-risk HPV infection[J]. Journal of Army Medical University, 2024, 46(6): 618-622. DOI： 10.16016/j.2097-0927.202307078.

摘要

目的

探讨团体认知行为干预(cognitive behavioral therapy，CBT)对宫颈高危型人乳头瘤病毒(high risk human papillomavirus，HR-HPV)持续感染患者临床转归的影响，构建针对情绪障碍的HR-HPV持续感染患者的系统性心理干预治疗方案。

方法

选取HR-HPV持续感染合并情绪障碍患者，按照随机数字表法分为干预组(

=44)和对照组(

=45)：对照组给予健康宣教、随访监测，干预组在此基础上给予CBT干预，比较两组的临床转归及心理量表评分。

结果

随访6月及12月，HR-HPV感染消退率干预组高于对照组；而HR-HPV持续感染率及进展率干预组低于对照组(

0.05)。抑郁症筛查量表(PHQ-9)及广泛性焦虑量表(GAD-7)评分，干预结束后即刻、随访6月及12月，干预组均低于对照组(

0.05)；干预组干预结束后即刻、随访6月及12月评分均低于干预前(

0.05)；对照组干预前后评分差异无统计学意义(

0.05)。

结论

HR-HPV持续感染患者进行系统性心理干预治疗，有助于HR-HPV感染消退。

Abstract

Objective

To explore the effect of group cognitive behavioral therapy (CBT) on the clinical outcome of patients with persistent high-risk human papillomavirus (HR-HPV) infection

and to construct a systematic psychological intervention treatment program for persistent HR-HPV infection patients with emotional disorders.

Methods

A total of 96 patients with persistent HR-HPV infection complicated with emotional disorder admitted in our hospital from September 2021 to March 2022 were recruited

and then randomly divided into an intervention group (

=44) and a control group (

=45) after 5 of them were excluded due to personal reason. The control group received health education and follow-up monitoring

and the intervention group received group CBT intervention additionally. Their clinical outcomes and psychological scale scores were compared between the 2 groups.

Results

In a follow-up for 6 and 12 months

the regression rate of HR-HPV infection was higher

and the sustained infection rate and progression rate of HR-HPV in the intervention group than the control group (

0.05). The intervention group also obtained lower scores of Nine-Item Patient Health Questionnaire (PHQ-9) and generalized anxiety scale (GAD-7) immediately after the intervention

and 6 and 12 months in follow-up for when compared with the control group (

0.05). And the scores at above time points were statistically lower than those before intervention in the intervention group (

0.05)

but no such differences were observed in the control group (

0.05).

Conclusion

Systematic psychological intervention treatment is beneficial to HR-HPV infection subside for patients with persistent HR-HPV infection.

关键词

Keywords

references

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