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1.100853 北京,解放军医学院 解放军总医院第六医学中心心血管病医学部
2.100034 北京,中国人民解放军第三〇五医院心血管内科
3.264299 山东 威海,中国人民解放军第九七〇医院心血管内科
4.735199 甘肃 嘉峪关,甘肃省嘉峪关市中医院心血管内科
5.101149 北京,通州离职干部休养所门诊部
[付振虹,E-mail: fuzhenh@126.com FU Zhenhong, E-mail: fuzhenh@126.com
收稿:2023-02-08,
修回:2023-09-01,
纸质出版:2024-05-30
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沈建, 张昕, 刘赫男, 等. 高温高湿环境下军事训练致新兵横纹肌溶解及相关脏器损伤的研究[J]. 陆军军医大学学报, 2024,46(10):1063-1067.
Jian SHEN, Xin ZHANG, Henan LIU, et al. Rhabdomyolysis and related organ damage in new recruits during military training under high temperature and humidity environment[J]. Journal of Army Medical University, 2024, 46(10): 1063-1067.
沈建, 张昕, 刘赫男, 等. 高温高湿环境下军事训练致新兵横纹肌溶解及相关脏器损伤的研究[J]. 陆军军医大学学报, 2024,46(10):1063-1067. DOI: 10.16016/j.2097-0927.202302047.
Jian SHEN, Xin ZHANG, Henan LIU, et al. Rhabdomyolysis and related organ damage in new recruits during military training under high temperature and humidity environment[J]. Journal of Army Medical University, 2024, 46(10): 1063-1067. DOI: 10.16016/j.2097-0927.202302047.
目的
2
通过比较不同训练环境对新兵实验室检测指标及心电图的影响,探讨新兵在高温高湿环境下出现横纹肌溶解和相关脏器损伤的可能性。
方法
2
选择两地新兵500名,均为男性,年龄(21.36±2.59)岁,按新兵所在环境分为常规环境组(北京某部,
n
=250)和高温高湿环境组(海南某部,
n
=250)。进行相同科目训练后4周,采集新兵的一般情况、训练前后血液及尿液学指标、心电图检查相关指标,并进行统计学分析。
结果
2
高温高湿环境组炎症反应、心肌损伤、肌肉损伤、肝损伤、肾损伤的发生率分别为45.76%、3.39%、12.71%、25.42%、12.71%,较常规环境组显著增加(
P
<
0.05)。高温高湿环境组新兵窦性心动过缓、房性早搏、非特异ST-T变化、左室高电压、短PR间期的发生率分别为6.78%、5.93%、8.47%、6.78%、2.54%,显著高于常规环境组(
P
<
0.05)。
结论
2
高温高湿环境下新兵军事训练后更易出现炎性反应、心肌损伤、肌肉损伤、肝损伤、肾损伤以及心电异常。
Objective
2
To explore the possibility of rhabdomyolysis and related organ damage in new recruits training in high temperature and high humidity environment by comparing the effects of different training environments on the laboratory indicators and electrocardiogram.
Methods
2
A total of 250 new recruits from a unit in Beijing and another 250 ones from a unit in Hainan were recruited and assigned into conventional environment group and high temperature and high humidity environment group
respectively. All of them were male
with an average age of 21.36±2.59 years. Before and in 4 weeks after training in the same subjects
their general information
blood and urine indicators
and electrocardiogram were collected. All data were statistically analyzed.
Results
2
The incidences of inflammatory reaction
myocardial injury
muscle injury
liver injury
and kidney injury were 45.76%
3.39%
12.71%
25.42%
and 12.71%
respectively
in the high temperature and high humidity environment group
which were all significantly higher than those in the conventional environment group (
P
<
0.05). The former group had an incidence rate of 6.78%
5.93%
8.47%
6.78%
and 2.54%
respectively
in sinus bradycardia
atrial premature beats
unspecific ST-T changes
left ventricular hypertension and short PR interval
and all of the rates were higher than those of the conventional environment group (
P
<
0.05).
Conclusion
2
The incidences of inflammatory reaction
myocardial injury
muscle injury
liver injury
kidney injury
and ECG abnormalities are more common in new recruits after military training in high temperature and high humidity environment.
MAO H D, LI X, LIU S Y, et al . Exertional rhabdomyolysis in newly enrolled cadets of a military academy[J ] . Muscle Nerve, 2021, 64(3): 336-341. DOI: 10.1002/mus.27355.
KIM J, LEE J, KIM S, et al . Exercise-induced rhabdomyoly-sis mechanisms and prevention: a literature review[J ] . J Sport Health Sci, 2016, 5(3): 324-333. DOI: 10.1016/j.jshs.2015.01.012.
CARNEIRO A, VIANA-GOMES D, MACEDO-DA-SILVA J, et al . Risk factors and future directions for preventing and diagnosing exertional rhabdomyolysis[J ] . Neuromuscul Disord, 2021, 31(7): 583-595. DOI: 10.1016/j.nmd.2021.04.007.
王劭亮, 陈蓉, 王明欢. 运动性横纹肌溶解症37例诊治分析[J]. 中华临床医师杂志(电子版), 2020, 14(1): 35-38. DOI: 10.3877/cma.j.issn.1674-0785.2020.01.008.
WANG S L, CHEN R, WANG M H. Diagnosis and treatment of 37 cases of athletic rhabdomyolysis[J]. Chin J Clinicians (Elec Ed), 2020, 14(1): 35-38. DOI: 10.3877/cma.j.issn.1674-0785.2020.01.008.
Update: exertional rhabdomyolysis, active component, U.S. armed forces, 2014-2018[J]. MSMR, 2019, 26(4): 21-25.
EICHNER E R. Exertional rhabdomyolysis in civilian and military populations[J]. Curr Sports Med Rep, 2020, 19(3): 99-100. DOI: 10.1249/jsr.0000000000000690.
SHUMWAY J, IRVIN A, SHIA R, et al . Biomarkers, creatine kinase, and kidney function of special operation candidates during intense physiological training[J ] . Mil Med, 2020, 185(7/8): e982-e987. DOI: 10.1093/milmed/usaa079.
LUETMER M T, BOETTCHER B J, FRANCO J M, et al . Exertional rhabdomyolysis: a retrospective population-based study[J ] . Med Sci Sports Exerc, 2020, 52(3): 608-615. DOI: 10.1249/MSS.0000000000002178.
谢冬冰. 热射病并发急性肝损伤、横纹肌溶解及继发肺渗出性病变1例[J]. 中国现代医药杂志, 2021, 23(3): 84-86. DOI: 10.3969/j.issn.1672-9463.2021.03.022.
XIE D B. A case of thermoplegia complicated with acute liver injury, rhabdomyolysis, and secondary pulmonary exudative lesions[J]. Mod Med J China, 2021, 23(3): 84-86. DOI: 10.3969/j.issn.1672-9463.2021.03.022.
WU M, WANG C L, LIU Z Y, et al . Sequential organ failure assessment score for prediction of mortality of patients with rhabdomyolysis following exertional heatstroke: a longitudinal cohort study in Southern China[J ] . Front Med (Lausanne), 2021, 8: 724319. DOI: 10.3389/fmed.2021.724319.
孙宏艳. 青少年体育运动状况调查及对策[J]. 青年学报, 2022(2): 68-78. DOI: 10.3969/j.issn.2095-7947.2022.02.009.
SUN H Y. Investigation and countermeasures on sports status of teenagers[J]. Youth Res, 2022(2): 68-78. DOI: 10.3969/j.issn.2095-7947.2022.02.009.
KUMAR R, KUMAR S, KUMAR A, et al . Exercise-induced rhabdomyolysis causing acute kidney injury: a potential threat to gym lovers[J ] . Cureus, 2022, 14(8): e28046. DOI: 10.7759/cureus.28046.
DAI R X, MENG Q. Exertional rhabdomyolysis combined with acute kidney injury and complicated by posterior reversible encephalopathy syndrome[J]. Intern Med, 2022, 61(24): 3729-3732. DOI: 10.2169/internalmedicine.9376-22.
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