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战创伤休克早期救治研究进展与思考
Advances and thinking for early treatment of war wound and traumatic shock
- 陆军军医大学学报 2022年44卷第20期 页码：2025-2029
- 作者机构：
400042 重庆，陆军特色医学中心战伤休克与输血研究室，创伤、烧伤与复合伤国家重点实验室
- 作者简介：
[ 刘良明，博士，专业技术少将研究员，博士研究生导师。国家杰出青年科学基金获得者，军队高层次创新人才。任创伤、烧伤与复合伤国家重点实验室常务副主任，中国病理生理学会休克专业委员会和中国研究型医院学会休克与脓毒症专业委员会副主任委员，国家卫健委应急处置专家，军委科技委创新特区主题专家。承担国家973计划、国家科技重大专项军特需药、国家自然科学基金重点项目、军队“十二五” “十三五”重大项目等20多项课题研究。以第一完成人获国家科技进步二等奖2项、省部级一、二等奖5项。以第一/通讯作者在Lancet, Cell Res, JAMA Intern Med, Sci Adv, Nat Com, JEM, Ann Surg, Cardiovas Res等发表学术论文350余篇(SCI收录期刊120余篇)。主编、副主编专著7部。主要从事战伤急救与战创伤休克防治方面的研究。E-mail: lmliu62@tmmu.edu.cn LIU Liangming, E-mail: lmliu62@tmmu.edu.cn
- 基金信息：
DOI：10.16016/j.2097-0927.202205151
中图分类号： R605.971;R826.1收稿：2022-05-27，
修回：2022-06-29，
纸质出版：2022-10-30
- 稿件说明：
移动端阅览
刘良明. 战创伤休克早期救治研究进展与思考[J]. 陆军军医大学学报, 2022,44(20):2025-2029.
Liangming LIU. Advances and thinking for early treatment of war wound and traumatic shock[J]. Journal of Army Medical University, 2022, 44(20): 2025-2029.
刘良明. 战创伤休克早期救治研究进展与思考[J]. 陆军军医大学学报, 2022,44(20):2025-2029. DOI： 10.16016/j.2097-0927.202205151.
Liangming LIU. Advances and thinking for early treatment of war wound and traumatic shock[J]. Journal of Army Medical University, 2022, 44(20): 2025-2029. DOI： 10.16016/j.2097-0927.202205151.
摘要
战创伤休克是战创伤患者早期死亡的重要原因。近年来针对战创伤休克早期救治，国际上提出了很多新的理念和技术
如限制性液体复苏、允许性低压复苏和延长黄金救治时间窗等。基于我军卫勤保障和战伤救治任务，本文重点分析高原高寒和海战伤休克的特点，并从线粒体功能保护角度提出的抗休克新措施；探讨脓毒症后肠道和血管屏障功能发生机制及新的保护措施，以及苹果酸新型复苏液体；同时，从新型复苏液体研究、新的救治靶点寻找讨论了战创伤休克救治研究趋势和方向。
Abstract
Traumatic shock is a main cause for early death of war wound and trauma. As for the early treatment of war wound and traumatic shock
many new concepts and techniques have been raised in recent years
such as limited fluid resuscitation
permissive fluid resuscitation and expanding golden hour care window. Based on the needs of our medical support and combat casualty care
the features and new treatment measures of war wound and traumatic shock at high altitude and marine
we discuss the new mechanisms and treatments of intestinal and vascular barrier function after sepsis and the new anti-shock fluids-malic acid fluid
and bring forward to the future research trends based on the new types of resuscitative fluid and new targets for war wound and traumatic shock.
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references
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