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儿童椎管内结核瘤的MRI特征分析
Magnetic resonance imaging features of intraspinal tuberculosis in children
- 陆军军医大学学报 2022年44卷第14期 页码：1472-1477
- 作者机构：
1.400014 重庆，重庆医科大学附属儿童医院放射科，国家儿童健康与疾病临床医学研究中心，儿童发育疾病研究教育部重点实验室，儿科学重庆市重点实验室
2.400038 重庆，陆军军医大学(第三军医大学)第一附属医院神经内科
- 作者简介：
[秦勇，E-mail：308787364@qq.comQIN Yong, E-mail: 308787364@qq.com
- 基金信息：国家自然科学基金面上项目(81771892)
DOI：10.16016/j.2097-0927.202203178
中图分类号： R445.2;R529.9;R739.42收稿：2022-03-18，
修回：2022-03-30，
纸质出版：2022-07-30
- 稿件说明：
移动端阅览
付园乔, 秦勇, 周怡睿, 等. 儿童椎管内结核瘤的MRI特征分析[J]. 陆军军医大学学报, 2022,44(14):1472-1477.
Yuanqiao FU, Yong QIN, Yirui ZHOU, et al. Magnetic resonance imaging features of intraspinal tuberculosis in children[J]. Journal of Army Medical University, 2022, 44(14): 1472-1477.
付园乔, 秦勇, 周怡睿, 等. 儿童椎管内结核瘤的MRI特征分析[J]. 陆军军医大学学报, 2022,44(14):1472-1477. DOI： 10.16016/j.2097-0927.202203178.
Yuanqiao FU, Yong QIN, Yirui ZHOU, et al. Magnetic resonance imaging features of intraspinal tuberculosis in children[J]. Journal of Army Medical University, 2022, 44(14): 1472-1477. DOI： 10.16016/j.2097-0927.202203178.
摘要
目的
2
探讨儿童椎管内结核瘤的核磁共振成像(magnetic resonance imaging，MRI)特征。
方法
2
回顾性分析重庆医科大学附属儿童医院2008-2021年经手术病理或随访证实的22例儿童椎管内结核瘤的临床和MRI资料，按部位分为3组：髓内5例，髓外硬膜下8例，硬膜外9例。分析病变的形态、MRI信号和强化模式等特征。
结果
2
髓内结核瘤呈圆形或类圆形，而髓外硬膜下和硬膜外结核瘤呈长梭形或斑块状；髓内和髓外结核瘤MRI信号均以T1WI等信号(15/22)、T2WI低信号(11/22)或等信号(7/22)为主；增强后髓内结核瘤呈环形强化(5/5)，而髓外结核瘤多为显著均匀强化(13/17)。10例(10/22)椎管内结核瘤发生于抗结核治疗中，其中髓外硬膜下结核瘤7例(7/8)，发生率显著高于硬膜外结核瘤(2/9)和髓内结核瘤(1/5)。
结论
2
儿童椎管内结核瘤MRI显示T1WI等、T2WI低/等信号以及环形或明显均匀强化；抗结核治疗过程中及时MRI检查有利于尽早发现椎管内结核瘤病变。
Abstract
Objective
2
To investigate the features of magnetic resonance imaging (MRI) of intraspinal tuberculoma in children.
Methods
2
The clinical and MRI data of 22 child patients with intraspinal tuberculoma confirmed by surgical pathology or by clinical follow-up in our department during 2008 and 2021 were collected and retrospectively reviewed. According to the location of tumor
they were divided into intramedullary (
n
=5)
intradural extramedullary (
n
=8) and epidural tuberculoma (
n
=9) groups. The lesion shapes
signal and enhancement patterns were analyzed.
Results
2
Intramedullary tuberculoma had a round or round-like shape
while extramedullary tuberculoma presented as long-fusiform or en plaque shapes. Both intramedullary tuberculoma and extramedullary tuberculoma were mainly isointense (15/22) on T1-weighted images (T1WI) and hypointense (11/22) or isointense (7/22) on T2WI. Rim enhancement (5/5) was observed in intramedullary tuberculoma
and remarkable homogeneous enhancement (13/17) was dominant in extramedullary tuberculoma. The intraspinal tuberculomas occurred during anti-tuberculosis therapy in 10 cases
including 7 cases (7/8) of intradural extramedullary tuberculomas
with a significantly higher rate than epidural tuberculoma (2/9) or intramedullary tuberculoma (1/5). Conclusion MRI of intraspinal tuberculoma is characterized by isointense on T1WI
hypointense/isointense on T2WI
and rim or remarkable homogeneous enhancement. The occurrence of intraspinal tuberculoma should be vigilant during anti-tuberculosis treatment. Timely MRI examination is beneficial to early detection of intraspinal lesions.
关键词
Keywords
references
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