浏览全部资源
扫码关注微信
254例突发性耳聋预后的影响因素分析
Prognostic factors of sudden sensorineural hearing loss: analysis of 254 cases
- 陆军军医大学学报 2022年44卷第4期 页码：385-389
- 作者机构：
401120 重庆，重庆医科大学附属第三医院耳鼻咽喉科
- 作者简介：
[李洪涛，E-mail: lihongtao871066@163.com LI Hongtao, E-mail: lihongtao871066@163.com
- 基金信息：
DOI：10.16016/j.2097-0927.202108215
中图分类号： R195.4;R764.437收稿：2021-08-30，
修回：2021-09-26，
纸质出版：2022-02-28
- 稿件说明：
移动端阅览
刘佳丽, 李洪涛. 254例突发性耳聋预后的影响因素分析[J]. 陆军军医大学学报, 2022,44(4):385-389.
Jiali LIU, Hongtao LI. Prognostic factors of sudden sensorineural hearing loss: analysis of 254 cases[J]. Journal of Army Medical University, 2022, 44(4): 385-389.
刘佳丽, 李洪涛. 254例突发性耳聋预后的影响因素分析[J]. 陆军军医大学学报, 2022,44(4):385-389. DOI： 10.16016/j.2097-0927.202108215.
Jiali LIU, Hongtao LI. Prognostic factors of sudden sensorineural hearing loss: analysis of 254 cases[J]. Journal of Army Medical University, 2022, 44(4): 385-389. DOI： 10.16016/j.2097-0927.202108215.
摘要
目的
2
探讨突发性耳聋预后的影响因素。
方法
2
收集2017-2020年于我科住院的254例不同年龄及不同听力损失的突发性耳聋患者，分析性别、患耳侧别、血脂、年龄、就医时间、听力下降曲线类型、是否伴眩晕等与预后之间的相关性，比较分析不同年龄组患者的预后。
结果
2
254例单耳突发性耳聋患者治疗总有效率为61.42%，12~40岁组治疗有效率为72.57%，41~60岁组57.94%，61~82岁组35.29%；61~82岁组治疗有效率与12~40岁组、41~60岁组比较差异有统计学意义(
P
＜0.05)。患者疗效与性别、患耳侧别、总胆固醇及甘油三酯水平无关。将对预后有影响的因素(年龄、病程、听力下降曲线类型、伴眩晕)进行多因素Logistic回归分析，结果显示在3个年龄组中61~82岁组患者预后最差，差异有统计学意义(
P
=0.005)。
结论
2
年龄、病程、听力下降曲线类型、伴眩晕因素与预后有关，年龄超过60岁突发性耳聋患者预后明显较差。
Abstract
Objective
2
To analyze the influencing factors on the prognosis of sudden deafness.
Methods
2
Clinical data of 254 patients with sudden deafness at different ages and with different hearing loss who were hospitalized in our department from January 2017 to December 2020 were collected and analyzed. The correlation of gender
affected ear side
blood lipid
age
course of disease
type of hearing curve
and dizziness or not with prognosis were analyzed. The prognosis was mainly analyzed for patients of different age groups.
Results
2
The total of effective rate of treatment was 61.42% for the 254 patients with sudden deafness in single ear. The effective rate was 72.57%
57.94% and 35.29% in the 12~40
41~60
61~82 year-old groups
respectively
and statistical difference was seen in the 61~82 year-old group with the 12~40 and 41~60 year-old groups (
P
<
0.05). There were no correlation of the efficacy with gender
ear side
total cholesterol and triglyceride levels. In the multivariate logistic regression analysis on the prognostic factors (age
course of disease
type of hearing curve and dizziness)
the results found that the 61~82 year-old group had the worst prognosis among the 3 age groups (
P
=0.005).
Conclusion
2
Age
course of disease
type of hearing curve and dizziness are related to prognosis. The prognosis of sudden deafness patients over 60 years old is significantly worse than that of 12-40 year-old group and 41-60 year-old group.
关键词
Keywords
references
余力生, 杨仕明. 突发性聋诊断和治疗指南(2015)[J]. 中华耳鼻咽喉头颈外科杂志, 2015, 50(6): 443-447.
YU L S, YANG S M. Guidelines for the diagnosis and treatment of sudden sensorineural hearing loss(2015)[J]. Chin J Otorhinolaryngol Head Neck Surg, 2015, 50(6): 443-447.
张静. 从《中国成人血脂异常防治指南》更新看血脂异常的管理[J]. 中华实用诊断与治疗杂志, 2017, 31(1): 1-3. DOI: 10.13507/j.issn.1674-3474.2017.01.001.
ZHANG J. Viewing the management of dyslipidemia from the update of "Guidelines for the Prevention and Treatment of Dyslipidemia in Adults in China"[J]. J Chin Pract Diagn Ther, 2017, 31(1): 1-3. DOI: 10.13507/j.issn.1674-3474.2017.01.001.
余茜, 李端超, 钟时勋. 糖皮质激素在治疗突发性耳聋中的应用[J]. 中华耳科学杂志, 2020, 18(2): 394-398. DOI: 10.3969/j.issn.1672-2922.2020.02.034.
YU Q, LI D C, ZHONG S X. Glucocorticoids in the treatment of sudden sensorineural hearing loss[J]. Chin J Otol, 2020, 18(2): 394-398. DOI: 10.3969/j.issn.1672-2922.2020.02.034.
文艺, 吕萍, 石敏, 等. 突发性聋的分型及药物治疗研究现状[J]. 中华耳科学杂志, 2021, 19(2): 301-305. DOI: 10.3969/j.issn.1672-2922.2021.02.023.
WEN Y, LYU P, SHI M, et al . Current research on classification and drug therapies of sudden hearing loss[J ] . Chin J Otol, 2021, 19(2): 301-305. DOI: 10.3969/j.issn.1672-2922.2021.02.023.
丁莉, 陶静, 叶菁. 甲钴胺联合银杏叶注射液治疗2型糖尿病耳聋耳鸣疗效观察[J]. 中国现代医生, 2017, 55(1): 58-60.
DING L, TAO J, YE J. Observation of curative effect of mecobalamin combined with Ginkgo biloba injection in the treatment of type 2 diabetes complicated with deafness and tinnitus[J]. China Mod Dr, 2017, 55(1): 58-60.
金焕庭. 鼠神经生长因子对突发性耳聋的临床效果研究[J]. 中国实用医药, 2018, 13(18): 141-142. DOI: 10.14163/j.cnki.11-5547/r.2018.18.082.
JIN H T. Study on the clinical effect of mouth nerve growth factor on sudden deafness[J]. China Pract Med, 2018, 13(18): 141-142. DOI: 10.14163/j.cnki.11-5547/r.2018.18.082.
KITOH R, NISHIO S Y, OGAWA K, et al . Nationwide epidemiological survey of idiopathic sudden sensorineural hearingloss in Japan[J ] . Acta Otolaryngol, 2017, 137(sup565): S8-S16. DOI: 10.1080/00016489.2017.1297537.
陈晓萍, 梁小龙, 童雷. 突发性耳聋患者的预后影响因素分析[J]. 现代实用医学, 2020, 32(11): 1353-1354, 1410. DOI: 10.3969/j.issn.1671-0800.2020.11.023.
CHEN X P, LIANG X L, TONG L. Analysis of prognostic factors in patients with sudden deafness[J]. Mod Pract Med, 2020, 32(11): 1353-1354, 1410. DOI: 10.3969/j.issn.1671-0800.2020.11.023.
FLORA G D, NAYAK M K. A brief review of cardiovascular diseases, associated risk factors and current treatment regimes[J]. Curr Pharm Des, 2019, 25(38): 4063-4084. DOI: 10.2174/1381612825666190925163827.
SHAO M, XIONG G, XIANG G, et al . Correlation between serum lipid and prognosis of idiopathic sudden sensorineural hearing loss: a prospective cohort study[J ] . Ann Transl Med, 2021, 9(8): 676. DOI: 10.21037/atm-21-907.
代佳. 青中年突发性耳聋患者的临床研究分析[D]. 郑州: 郑州大学, 2020.
DAI J. Clinical analysis of sudden deafness(sudden sensorineural hearing loss) in young and middle-aged patients[D]. Zhengzhou: Zhengzhou University, 2020.
屈双燕. 中老年突发性耳聋患者的临床特征、转归及预后[J]. 中国老年学杂志, 2014, 34(11): 3013-3015. DOI: 10.3969/j.issn.1005-9202.2014.11.049.
QU S Y. Clinical characteristics, outcome and prognosis of middle-aged and elderly patients with sudden sensorineural hearing loss[J]. Chin J Gerontol, 2014, 34(11): 3013-3015. DOI: 10.3969/j.issn.1005-9202.2014.11.049.
CIORBA A, CORAZZI V, BIANCHINI C, et al . Sudden sensorineural hearing loss: Is there a connection with inner ear electrolytic disorders? A literature review[J ] . Int J Immunopathol Pharmacol, 2016, 29(4): 595-602. DOI: 10.1177/0394632016673845.
QIN H, HE B H, WU H, et al . Visualization of endolymphatic Hydrops in patients with unilateral idiopathic sudden sensorineural hearin g loss with four types according to Chinese criterion[J ] . Front Surg, 2021, 8: 682245. DOI: 10.3389/fsurg.2021.682245.
CAVALIERE M, DE LUCA P, SCARPA A, et al . SCORE risk scale as a prognostic factor after sudden sensorineural hearing loss[J ] . Eur Arch Otorhinolaryngol, 2020, 277(3): 953-954. DOI: 10.1007/s00405-019-05771-4.
KANG W S, YANG C J, SHIM M, et al . Prognostic factors for recovery from sudden sensorineural hearing loss: a retrospective study[J ] . J Audiol Otol, 2017, 21(1): 9-15. DOI: 10.7874/jao.2017.21.1.9.
KOVÁCS M, UZSALY J, BODZAI G, et al . Analysis of prognostic factors influencing the effectiveness of treatment in sudden sensorineural hearing loss[J ] . Orv Hetil, 2019, 160(18): 687-693. DOI: 10.1556/650.2019.31368.
[ SHIMANUKI M N, SHINDEN S, OISHI N, et al . Early hearing improvement predicts the prognosis of idiopathic sudden sensorineural hearing loss[J ] . Eur Arch Otorhinolaryngol, 2021. [Online ahead of print ] . DOI: 10.1007/s00405-020-06532-4 http://dx.doi.org/10.1007/s00405-020-06532-4 ..
魏彩娥. 突发性耳聋的预后及相关影响因素[D]. 乌鲁木齐: 新疆医科大学, 2020.
WEI C E. Prognosis and related influencing factors of sudden deafness[D]. Urumqi: Xinjiang Medical University, 2020.
冰丹, 兰兰, 关静, 等. 年龄对突发性耳聋的预后影响[J]. 中华耳科学杂志, 2018, 16(3): 312-318.
BING D, LAN L, GUAN J, et al . Age and prognosis of sudden deafness[J ] . Chin J Otol, 2018, 16(3): 312-318.
0
浏览量
0
下载量
0
CSCD
- 网络PDF下载
- Meta-XML下载
- BibTeX下载
- Endnote下载
- RefMan 下载
- NoteExpress下载
- NoteFirst下载
关联资源
相关文章
相关作者
相关机构
- 技术支持由北京北大方正电子有限公司提供 京ICP备09064830号-19
京公网安备11010802024621 - 本系统建议在Chrome、 IE9+ 以上版本浏览器阅读本站内容，360浏览器请切换至极速模式
- Cookies帮助我们提供服务并提供个性化体验。使用本网站，即表示您同意我们使用Cookies
