多导睡眠监测研究围绝经期女性失眠障碍的临床特征

赵媛; 陈庆秋; 蒋成刚

doi:10.16016/j.1000-5404.202103229

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多导睡眠监测研究围绝经期女性失眠障碍的临床特征

神经科学 | 更新时间：2026-01-09

- 多导睡眠监测研究围绝经期女性失眠障碍的临床特征
- Clinical characteristics of insomnia in perimenopausal women: a clinical study based on polysomnography
- 第三军医大学学报 2021年43卷第19期页码：1854-1859
- 作者机构：
  
  1.401120 重庆，重庆市妇幼保健院心理科
  2.400038 重庆，陆军军医大学(第三军医大学)第一附属医院乳腺甲状腺外科
- 作者简介：
  
  [陈庆秋，E-mail: 124519539@qq.com CHEN Qingqiu, E-mail: 124519539@qq.com
  [蒋成刚，E-mail: fybjy123jcg@163.com JIANG Chenggang, E-mail: fybjy123jcg@163.com
- 基金信息：
  
  重庆市技术创新与应用发展项目(cstc2019jscx-msxmX0124)
- DOI：10.16016/j.1000-5404.202103229
  中图分类号： R338.63;R711.51;R741.044
- 收稿：2021-03-27，
  
  修回：2021-04-27，
  
  纸质出版：2021-10-15
- 稿件说明：
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赵媛, 陈庆秋, 蒋成刚. 多导睡眠监测研究围绝经期女性失眠障碍的临床特征[J]. 第三军医大学学报, 2021,43(19):1854-1859.

Yuan ZHAO, Qingqiu CHEN, Chenggang JIANG. Clinical characteristics of insomnia in perimenopausal women: a clinical study based on polysomnography[J]. Journal of Third Military Medical University, 2021, 43(19): 1854-1859.
赵媛, 陈庆秋, 蒋成刚. 多导睡眠监测研究围绝经期女性失眠障碍的临床特征[J]. 第三军医大学学报, 2021,43(19):1854-1859. DOI： 10.16016/j.1000-5404.202103229.

Yuan ZHAO, Qingqiu CHEN, Chenggang JIANG. Clinical characteristics of insomnia in perimenopausal women: a clinical study based on polysomnography[J]. Journal of Third Military Medical University, 2021, 43(19): 1854-1859. DOI： 10.16016/j.1000-5404.202103229.

摘要

目的

基于多导睡眠监测探讨围绝经期女性失眠障碍的临床特征及其影响因素。

方法

本研究纳入2020年10月至2021年2月于重庆市妇幼保健院心理科门诊就诊的52名围绝经期女性，根据匹兹堡睡眠指数量表(Pittsburgh Sleep Quality Index

PSQI)结果分为研究组(PSQI≥7分)和对照组(PSQI < 7分)，采用多导睡眠监测(polysomnography，PSG)记录睡眠状况，采用围绝经期评定量表(Menopause Rating Scale

MRS)测量围绝经期相关症状。比较两组PSG监测睡眠相关指标及MRS结果差异，并分析各睡眠指标与围绝经期症状的关系。

结果

① 围绝经期女性研究组睡眠总时间、睡眠效率较对照组明显下降(

0.05)；研究组入睡潜伏期、入睡后清醒时间等指标则明显高于对照组(

0.05)；②围绝经期女性失眠障碍伴有快速眼动(rapid eye movement

REM)期睡眠紊乱的临床特点，与对照组比较，研究组REM睡眠总时间、REM睡眠比例降低，REM睡眠潜伏期延长，REM转清醒次数增加(

0.05)；③研究组MRS总分(26.69±5.13)、躯体症状评分(9.49±2.92)、心理症状评分(10.34±2.95)、泌尿生殖系统评分(6.86±2.89)均高于对照组(

0.05)；④REM睡眠比例、REM睡眠总时间与抑郁情绪呈负相关(

0.05)，REM睡眠潜伏期与焦虑、性生活质量呈正相关(

0.05)。

结论

围绝经期女性失眠障碍表现为REM期睡眠紊乱，且REM期睡眠与焦虑、抑郁及性生活质量密切相关。

Abstract

Objective

To investigate the clinical characteristics and influencing factors of insomnia in perimenopausal women based on polysomnography (PSG).

Methods

A total of 52 perimenopausal women admitted to our psychological clinic due to insomnia were included in this study. According to the results of Pittsburgh sleep quality index (PSQI)

they were divided into study group (PSQI≥7) and control group (PSQI < 7). Sleep status was recorded by polysomnography (PSG)

and symptoms related to perimenopausal period were measured by menopause rating scale (MRS).The differences of PSG monitoring sleep-related indicators and MRS results were compared between the 2 groups

and the correlations of each sleep indicator with perimenopausal symptoms were analyzed.

Results

① The total sleep time and sleep efficiency were significantly decreased in the perimenopausal women from the study group than those from the control group (

0.05). The former group had obviously longer sleep latency and wakefulness time when compared with the latter group (

0.05). ② These perimenopausal women had the clinical feature of rapid eye movement (REM) sleep behavior

which were characterized by decreased total time of REM sleep

decreased proportion of REM sleep

prolonged latency of REM sleep

and increased frequency of REM to wakefulness in the study group when compared with the control group (

0.05). ③The total MRS score

somatic symptom score

psychological symptom score and genitourinary system score were 26.69±5.13

9.49±2.92

10.34±2.95 and 6.86±2.89

respectively

in the study group

which were all higher than those of the control group (

0.05). ④The proportion of REM sleep and the total time of REM sleep were negatively correlated with depression (

0.05)

while the latency of REM sleep was positively correlated with anxiety and sexual life quality (

0.05).

Conclusion

Insomnia in perimenopausal women is characterized by REM sleep disorder

and REM sleep is closely related to anxiety

depression and sexual life quality.

关键词

Keywords

references

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