过氧化氢低温等离子灭菌法对硬性透气性角膜接触镜试戴片的灭菌效果观察

陈利; 刘波; 杨微; 宋利兵; 何敏; 霍姝佳

doi:10.16016/j.1000-5404.202101067

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过氧化氢低温等离子灭菌法对硬性透气性角膜接触镜试戴片的灭菌效果观察

临床医学 | 更新时间：2026-01-09

- 过氧化氢低温等离子灭菌法对硬性透气性角膜接触镜试戴片的灭菌效果观察
- Sterilization effectiveness of hydrogen peroxide low temperature plasma on rigid gas permeable contact trial lens
- 第三军医大学学报 2021年43卷第13期页码：1275-1279
- 作者机构：
  
  400038 重庆，陆军军医大学(第三军医大学)第一附属医院眼科
- 作者简介：
  
  [霍姝佳，E-mail: bengkui8919@sina.comHUO Shujia, E-mail: bengkui8919@sina.com
- 基金信息：
  
  重庆市科卫联合医学科研项目(2021MSXM068)
- DOI：10.16016/j.1000-5404.202101067
  中图分类号： R187.2;R778.3
- 收稿：2021-01-07，
  
  修回：2021-03-26，
  
  纸质出版：2021-07-15
- 稿件说明：
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陈利, 刘波, 杨微, 等. 过氧化氢低温等离子灭菌法对硬性透气性角膜接触镜试戴片的灭菌效果观察[J]. 第三军医大学学报, 2021,43(13):1275-1279.

Li CHEN, Bo LIU, Wei YANG, et al. Sterilization effectiveness of hydrogen peroxide low temperature plasma on rigid gas permeable contact trial lens[J]. Journal of Third Military Medical University, 2021, 43(13): 1275-1279.
陈利, 刘波, 杨微, 等. 过氧化氢低温等离子灭菌法对硬性透气性角膜接触镜试戴片的灭菌效果观察[J]. 第三军医大学学报, 2021,43(13):1275-1279. DOI： 10.16016/j.1000-5404.202101067.

Li CHEN, Bo LIU, Wei YANG, et al. Sterilization effectiveness of hydrogen peroxide low temperature plasma on rigid gas permeable contact trial lens[J]. Journal of Third Military Medical University, 2021, 43(13): 1275-1279. DOI： 10.16016/j.1000-5404.202101067.

摘要

目的

对比过氧化氢低温等离子灭菌法与传统镜片消毒方法对硬性角膜接触镜试戴片的消毒效果。

方法

选择2020年4-8月来我院验配硬性角膜接触镜患者使用后的试戴片90片。根据镜片消毒方式分为3组，A组采用改良后的过氧化氢低温等离子灭菌法(30片)，B组采用传统护理液消毒(30片)，C组采用高分子材料注塑制成的抗菌镜盒消毒(30片)。采用美国赛默飞Versa TREK 528全自动微生物培养系统检测试戴片保存液，共培养5 d，评估镜片消毒效果，每月检测1次，连续检测3个月。裂隙灯检查眼表情况，问卷调查评估试戴后舒适度。

结果

A组细菌培养均为阴性，灭菌效果100.0%；B组2次培养出现异常菌群，灭菌效果97.7%；C组1次培养出现异常菌群，灭菌效果98.9%。3种消毒方法差异无统计学意义。角膜健康检查与舒适度问卷调查显示3组消毒方法差异均无统计学意义。

结论

过氧化氢低温等离子灭菌法对硬性角膜接触镜试戴片消毒彻底，不仅可保障患者的安全，而且流程简洁，值得推广。

Abstract

Objective

To compare the disinfection effect of hydrogen peroxide low temperature plasma sterilization and traditional lens disinfection on rigid gas permeable contact lens (RGP)

so as to improve the clinical management procedure of RGP trial lens.

Methods

A total of 90 RGP trial lenses used by patients in our hospital from April to August 2020 were collected and randomly divided into 3 groups. Group A was treated with modified hydrogen peroxide low temperature plasma sterilizing method (

=30); group B was disinfected with conventional conditioning solution (

=30); and group C was sterilized with anti-bacterial case made of polymer injection material (

=30). The preserving solution of the 3 groups was respectively cultured for 5 d and then tested with the automatic microbial culture system of American Simmer TREK 528

and a comparison of the sterilization effect was made among the groups. The test was performed once a month for 3 months. Moreover

patients' ocular surface condition was examined with a slit lamp

and the comfort level after wearing was evaluated through questionnaire survey.

Results

The bacteria culture of group A was negative with the sterilization effect of 100.0%

while abnormal bacteria were detected 2 cases in group B and 1 case in group C

with the disinfection rates of 97.7% and 98.9%

respectively

though there was no statistical difference among the 3 disinfection methods. In addition

the results of corneal examination and comfort questionnaire survey showed no statistical difference among the groups as well.

Conclusion

Hydrogen peroxide low-temperature plasma sterilization has a thorough disinfection effect with a safe and simple procedure

and is worth popularizing.

关键词

Keywords

references

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