增生性瘢痕形成不同时期二氧化碳点阵激光治疗的效果分析

程静; 李娜; 杨丽; 胡大海; 韩军涛

doi:10.16016/j.1000-5404.202101044

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增生性瘢痕形成不同时期二氧化碳点阵激光治疗的效果分析

专题报道：皮肤创面与瘢痕修复研究 | 更新时间：2026-01-09

- 增生性瘢痕形成不同时期二氧化碳点阵激光治疗的效果分析
- Clinical efficacy of fractional carbon dioxide laser in treatment of hypertrophic scars at different stages
- 第三军医大学学报 2021年43卷第11期页码：1032-1038
- 作者机构：
  
  710032 西安，空军军医大学西京医院全军烧伤中心，烧伤与皮肤外科
- 作者简介：
  
  [韩军涛，E-mail: hanjt@fmmu.edu.cn HAN Juntao, E-mail: hanjt@fmmu.edu.cn
- 基金信息：
- DOI：10.16016/j.1000-5404.202101044
  中图分类号： R322.64;R329.28;R394.3
- 收稿：2021-01-05，
  
  修回：2021-04-08，
  
  纸质出版：2021-06-15
- 稿件说明：
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程静, 李娜, 杨丽, 等. 增生性瘢痕形成不同时期二氧化碳点阵激光治疗的效果分析[J]. 第三军医大学学报, 2021,43(11):1032-1038.

Jing CHENG, Na LI, Li YANG, et al. Clinical efficacy of fractional carbon dioxide laser in treatment of hypertrophic scars at different stages[J]. Journal of Third Military Medical University, 2021, 43(11): 1032-1038.
程静, 李娜, 杨丽, 等. 增生性瘢痕形成不同时期二氧化碳点阵激光治疗的效果分析[J]. 第三军医大学学报, 2021,43(11):1032-1038. DOI： 10.16016/j.1000-5404.202101044.

Jing CHENG, Na LI, Li YANG, et al. Clinical efficacy of fractional carbon dioxide laser in treatment of hypertrophic scars at different stages[J]. Journal of Third Military Medical University, 2021, 43(11): 1032-1038. DOI： 10.16016/j.1000-5404.202101044.

摘要

目的

比较增生性瘢痕形成不同时期二氧化碳点阵激光治疗的效果。

方法

收集2018年1－6月本院门诊治疗符合入选标准的45例6~8个月增生性瘢痕患者，分为3组：对照组(

=12)、半年组(

=15)和1年组(

=18)。3组患者均给予常规治疗(压力治疗和药物治疗)，对照组不采用点阵激光治疗，半年组和1年组分别在形成增生性瘢痕半年(入组时)和1年(入组半年时)给予二氧化碳点阵激光治疗，间隔3个月治疗1次，入组时和形成增生性瘢痕2年时采用温哥华瘢痕评分量表(Vancouver Scar Scale，VSS)对瘢痕进行评估；并记录治疗次数、误工时间、不良反应和患者满意度。

结果

增生性瘢痕形成2年时，对照组VSS评分及瘢痕厚度和柔软度评分均明显高于半年组和1年组(

0.05)，半年组和1年组各评分差异无统计学意义(

0.05)。与1年组比较，半年组二氧化碳点阵激光治疗次数多(

0.05)，误工时间更长(

0.05)；但治疗后色素沉着发生率均较低，且差异无统计学意义(

0.05)。二氧化碳点阵激光治疗半年组和1年组患者满意度明显高于对照组(

0.05)。

结论

增生性瘢痕形成半年时和1年时采取二氧化碳点阵激光治疗均安全有效，且效果无明显差异。

Abstract

Objective

To compare the clinical efficacy of fractional carbon dioxide laser in the treatment of hypertrophic scars at different stages.

Methods

Forty-five patients with 6-~8-month hypertrophic scars who met our inclusion criteria and were admitted to our department from February 2018 to June 2018 were recruited in this study. They were divided into control group (

=12)

half-year group (

=15) and 1-year group (

=18). Each patient was treated with conventional treatments (stress and medication)

and the patients in the control group were not treated with laser

those in the half-year group and 1-year group were treated with carbon dioxide laser from scar formation for half year (at admission) and for 1 year (half year after admission)

respectively. Laser radiation were performed every 3 months. The scars were scored by Vancouver Scar Scale (VSS) at admission and 24 months after scar formation. The times of treatment

loss of working

incidence of side effects and patient satisfaction were also recorded.

Results

VSS score

scar thickness score and scar softness score were significantly higher in the control group than the half-year group and 1-year group (

0.05)

but no such statistical differences were seen between the latter 2 groups (

0.05). Compared with the 1-year group

the half-year group had obviously higher times of laser radiation (

0.05)

longer loss of working time (

0.05)

and similaryly lower incidence of pigmentation (

0.05). The patient satisfaction rate was notably higher in the half-year group and the 1-year group than that of control (

0.05).

Conclusion

It is safe and effective to treat hypertrophic scar with fractional carbon dioxide laser in half and 1 year after scar formation

and there are no obvious differences in the efficacy between the 2 time points.

关键词

Keywords

references

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