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100191 北京,北京大学公共卫生学院流行病与卫生统计学系
[胡永华,E-mail: yhhu@bjmu.edu.cn HU Yonghua, E-mail: yhhu@bjmu.edu.cn
收稿:2021-01-04,
修回:2021-02-15,
纸质出版:2021-06-30
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王伽婷, 王紫荆, 武轶群, 等. 北京地区115万2型糖尿病患者常见共患疾病的流行情况及特点[J]. 第三军医大学学报, 2021,43(12):1126-1132.
Jiating WANG, Zijing WANG, Yiqun WU, et al. Epidemiological status and characteristics of common comorbidities of type 2 diabetes mellitus among 1.15 million patients in Beijing area[J]. Journal of Third Military Medical University, 2021, 43(12): 1126-1132.
王伽婷, 王紫荆, 武轶群, 等. 北京地区115万2型糖尿病患者常见共患疾病的流行情况及特点[J]. 第三军医大学学报, 2021,43(12):1126-1132. DOI: 10.16016/j.1000-5404.202101017.
Jiating WANG, Zijing WANG, Yiqun WU, et al. Epidemiological status and characteristics of common comorbidities of type 2 diabetes mellitus among 1.15 million patients in Beijing area[J]. Journal of Third Military Medical University, 2021, 43(12): 1126-1132. DOI: 10.16016/j.1000-5404.202101017.
目的
2
了解北京地区2型糖尿病患者常见共患疾病的流行情况及特点。
方法
2
对北京地区2017年诊断为2型糖尿病的1 156 965例患者,收集其2016-2017年在各级医院的门诊和住院记录,并对记录进行整理与分析,描述该人群中高血压、缺血性心脏病、脑卒中、肺癌、慢性肾病、严重听力损失、抑郁症、视网膜病变和阻塞性肺疾病等9种疾病的患病情况,并比较不同年龄及性别亚组的差异。
结果
2
患者年龄(61.28±13.14)岁,男性占51.93%。有29.02%的研究对象患有至少一种共病,共病患病率随年龄的增长而增加,女性的共病患病率更高(
P
<
0.01)。患病率最高的4种疾病为高血压(20.16%),抑郁症(6.15%),缺血性心脏病(3.52%)和脑卒中(3.27%),女性更容易伴发高血压、抑郁症(
P
<
0.01),男性更容易伴发缺血性心脏病、脑卒中、阻塞型肺疾病、肺癌和慢性肾病(
P
<
0.01)。患者合并两种及以上共病的患病率为4.59%,其中共患病率最高的3种疾病组合为高血压和抑郁症(1.75%)、高血压和脑卒中(1.25%)、高血压和缺血性心脏病(1.16%),男性最常见共患病组合为高血压和脑卒中(1.51%),女性最常见共患病组合为高血压和抑郁症(2.12%)。
结论
2
2型糖尿病患者易伴发心血管代谢类疾病及抑郁症,女性更易伴发高血压和糖尿病,男性更易伴发其他系统及器官的疾病,疾病预后相对较差。
Objective
2
To investigate the epidemiological status and characteristics of common comorbidities among patients with type 2 diabetes mellitus (T2DM) in Beijing.
Methods
2
A total of 1 156 965 patients diagnosed with T2DM in 2017 in Beijing were recruited
and their outpatient and inpatient records at all levels of hospitals from 2016 to 2017 were collated and analyzed. The prevalence of 9 comorbidities in this population was described
including hypertension
ischemic heart disease
stroke
lung cancer
chronic kidney disease
severe hearing loss
depression
retinopathy and obstructive pulmonary disease. The differences among different genders and age groups were subsequently compared.
Results
2
The enrolled patients were at a mean age of 61.28±13.14 years
and the males accounted for 51.93%. Of them
29.02% had at least 1 comorbidity. The prevalence of comorbidities was increased with age
and the females had a higher prevalence of comorbidities than the males (
P
<
0.01). The 4 major comorbidities with the highest prevalence were hypertension (20.16%)
depression (6.15%)
ischemic heart disease (3.52%) and stroke (3.27%) in order. The females were more likely to suffer from hypertension and depression (
P
<
0.01)
while the males from ischemic heart disease
stroke
obstructive lung disease
lung cancer and chronic kidney disease (
P
<
0.01). The percentage of patients with 2 or more kinds of comorbidities accounted for 4.59%. The most commonly combined 2 diseases were hypertension with depression (1.75%)
hypertension with stroke (1.25%)
and hypertension with ischemic heart disease (1.16%). The most common comorbidities were hypertension and stroke in the males (1.51%)
and hypertension and depression in the females (2.12%).
Conclusion
2
T2DM patients are prone to cardiovascular and metabolic diseases as well as depression. The females are more likely to be accompanied with hypertension and depression
while the males with diseases of other systems and organs
and have relatively poor prognosis.
SAEEDI P, PETERSOHN I, SALPEA P, et al . Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: Results from the International Diabetes Federation Diabetes Atlas, 9th edition[J ] . Diabetes Res Clin Prac, 2019 157: 107843. DOI: 10.1016/j.diabres.2019.107843.
SINCLAIR A, SAEEDI P, KAUNDAL A, et al . Diabetes and global ageing among 65-99-year-old adults: Findings from the International Diabetes Federation Diabetes Atlas, 9th edition[J ] . Diabetes Res Clin Pract, 2020, 162: 108078. DOI: 10.1016/j.diabres.2020.108078.
WILLIAMS R, KARURANGA S, MALANDA B, et al . Global and regional estimates and projections of diabetes-related health expenditure: Results from the International Diabetes Federation Diabetes Atlas, 9th edition[J ] . Diabetes Res Clin Pract, 2020, 162: 108072. DOI: 10.1016/j.diabres.2020.108072.
MORLEY J E, ABBATECOLA A M, WOO J. Management of comorbidities in older persons with type 2 diabetes[J]. J Am Med Dir Assoc, 2017, 18(8): 639-645. DOI: 10.1016/j.jamda.2017.05.006.
MAGNAN E M, BOLT D M, GREENLEE R T, et al . Stratify- ing patients with diabetes into clinically relevant groups by combination of chronic conditions to identify gaps in quality of care[J ] . Health Serv Res, 2018, 53(1): 450-468. DOI: 10.1111/1475-6773.12607.
PIETTE J D, KERR E A. The impact of comorbid chronic conditions on diabetes care[J]. Diabetes Care, 2006, 29(3): 725-731. DOI: 10.2337/diacare.29.03.06.dc05-2078.
LUIJKS H, SCHERMER T, BOR H, et al . Prevalence and incidence density rates of chronic comorbidity in type 2 diabetes patients: an exploratory cohort study[J ] . BMC Med, 2012, 10: 128. DOI: 10.1186/1741-7015-10-128.
WOLFF J L, STARFIELD B, ANDERSON G. Prevalence, expenditures, and complications of multiple chronic conditions in theelderly[J]. Arch Intern Med, 2002, 162(20): 2269-2276. DOI: 10.1001/archinte.162.20.2269.
MAIR F S, MAY C R. Thinking about the burden of treatment[J]. BMJ, 2014, 349: g6680. DOI: 10.1136/bmj.g6680.
GBD 2019 Risk Factors ollaborators. Global burden of 87 risk factors in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019[J]. Lancet, 2020, 396(10258): 1223-1249. DOI: 10.1016/s0140-6736(20)30752-2.
DIEDERICHS C, BERGER K, BARTELS D B. The measure- ment of multiple chronic diseases: a systematic review on existing multimorbidity indices[J]. J Gerontol A Biol Sci Med Sci, 2011, 66(3): 301-311. DOI: 10.1093/gerona/glq208.
赵文颖, 赵冬, 王晓静, 等. 北京市通州区2型糖尿病患者多病共存现状及影响因素研究[J]. 中华健康管理学杂志, 2019(6): 541-545.
ZHAO W Y, ZHAO D, WANG X J, et al . Current status and influential factors of co-morbidity for patients with type 2 diabetes mellitus in Tongzhou district of Beijing[J ] . Chin J Health Manage, 2019(6): 541-545.
方家追. 2型糖尿病住院原因和慢性并发症患病率及其危险因素分析[D]. 杭州: 浙江大学, 2015.
FANG J Z. Hospitalization for type 2 diabetes mellitus and chronic diabetic complications and their risk factors[D]. Hangzhou: Zhejiang University, 2015.
CHEN H, CHEN H, ZHANG Y, et al . Comorbidity in adult patients hospitalized with type 2 diabetes in northeast China: an analysis of hospital discharge data from 2002 to 2013[J ] . Biomed Res Int, 2016, 2016: 1671965. DOI: 10.1155/2016/167196 5.
IGLAY K, HANNACHI H, JOSEPH HOWIE P, et al . Prevalence and co-prevalence of comorbidities among patients with type 2 diabetes mellitus[J ] . Curr Med Res Opin, 2016, 32(7): 1243-1252. DOI: 10.1185/03007995. 2016.1168291.
LYNCH C P, GEBREGZIABHER M, ZHAO Y, et al . Impact of medical and psychiatric multi-morbidity on mortality in diabetes: emerging evidence[J ] . BMC Endocr Disord, 2014, 14: 68. DOI: 10.1186/1472-6823-14-68.
TELJEUR C, SMITH S M, PAUL G, et al . Multimorbidity in a cohort of patients with type 2 diabetes[J ] . Eur J Gen Pract, 2013, 19(1): 17-22. DOI: 10.3109/13814788.2012.714768.
MATA-CASES M, FRANCH-NADAL J, REAL J, et al . Prevalence and coprevalence of chronic comorbid conditions in patients with type 2 diabetes in Catalonia: a population-based cross-sectional study[J ] . BMJ Open, 2019, 9(10): e031281. DOI: 10.1136/bmjopen-2019-031281.
HERMANS M P, DATH N. Prevalence and co-prevalence of comorbidities in Belgian patients with type 2 diabetes mellitus: a transversal, descriptive study[J]. Acta Clin Belg, 2018, 73(1): 68-74. DOI: 10.1080/17843286.2017.1348710.
付文, 何晓燕, 曹日芳, 等. 2型糖尿病患者情绪、应对及心理控制源调查[J]. 现代预防医学, 2018, 45(6): 1149-1152.
FU W, HE X Y, CAO R F, et al . Study on emotion, coping and locus of control in patients with type 2 diabetes mellitus[J ] . Mod Prevent Med, 2018, 45(6): 1149-1152.
PETRIE J R, GUZIK T J, TOUYZ R M. Diabetes, hypertension, and cardiovascular disease: clinical insights and vascular mechanisms[J]. Can J Cardiol, 2018, 34(5): 575-584. DOI: 10.1016/j.cjca.2017.12.005.
段姗姗, 刘代洪, 李婷, 等. 2型糖尿病对中年患者认知功能的影响及其特点[J]. 第三军医大学学报, 2016, 38(3): 314-319. DOI: 10.16016/j.1000-5404.201509122.
DUAN S S, LIU D H, LI T, et al . Effect of type 2 diabetes mellitus on cognitive function in middle-aged adults and its characteristics[J ] . J Third Mil Med Univ, 2016, 38(3): 314-319. DOI: 10.16016/j.1000-5404.201509122.
HOLT R I, DE GROOT M, GOLDEN S H. Diabetes and depression[J]. Curr Diab Rep, 2014, 14(6): 491. DOI: 10.1007/s11892-014-0491-3.
ANDERSON R J, FREEDLAND K E, CLOUSE R E, et al . The prevalence of comorbid depression in adults with diabetes: a meta-analysis[J ] . Diabetes Care, 2001, 24(6): 1069-1078. DOI: 10.2337/diacare.24.6.1069.
FORAN E, HANNIGAN A, GLYNN L. Prevalence of depression in patients with type 2 diabetes mellitus in Irish primary care and the impact of depression on the control of diabetes[J]. Ir J Med Sci, 2015, 184(2): 319-322. DOI: 10.1007/s11845-014-1110-7.
甘勇, 杨婷婷, 刘建新, 等. 深圳市中老年居民脑卒中患病率的性别差异及影响因素研究[J]. 中国预防医学杂志, 2020, 21(2): 121-126.
GAN Y, YANG T T, LIU J X, et al . Gender difference in prevalence of stroke and its related influencing factors among residents over 40 years old in Shenzhen[J ] . Chin Prev Med, 2020, 21(2): 121-126.
LUIJKS H, BIERMANS M, BOR H, et al . The effect of comorbidity on glycemic control and systolic blood pressure in type 2 diabetes: a cohort study with 5 year follow-up in primary care[J ] . PLoS ONE, 2015, 10(10): e0138662. DOI: 10.1371/journal.pone.0138662.
CHIANG J I, JANI B D, MAIR F S, et al . Associations between multimorbidity, all-cause mortality and glycaemia in people with type 2 diabetes: a systematic review[J ] . PLoS ONE, 2018, 13(12): e0209585. DOI: 10.1371/journal.pone.0209585.
CHIANG J I, HANLON P, LI T C, et al . Multimorbidity, mortality, and HbA1c in type 2 diabetes: a cohort study with UK and Taiwanese cohorts[J ] . PLoS Med, 2020, 17(5): e1003094. DOI: 10.1371/journal.pmed.1003094.
QUIÑONES A R, MARKWARDT S, BOTOSENEANU A. Diabetes-multimorbidity combinations and disability among middle-aged and older adults[J]. J Gen Intern Med, 2019, 34(6): 944-951. DOI: 10.1007/s11606-019-04896-w.
王雨东, 李传伟, 何多芬, 等. 高血压伴或不伴2型糖尿病患者血压晨峰与冠脉病变严重程度的相关性[J]. 第三军医大学学报, 2017, 39(1): 89-94. DOI: 10.16016/j.1000-5404.201607070.
WANG Y D, LI C W, HE D F, et al . Correlation of morning blood pressure surge with severity of coronary artery lesions in essential hypertension patients with or without type 2 diabetes mellitus[J ] . J Third Mil Med Univ, 2017, 39(1): 89-94. DOI: 10.16016/j.1000-5404.201607070.
GREENFIELD S, BILLIMEK J, PELLEGRINI F, et al . Comorbidity affects the relationship between glycemic control and cardiovascular outcomes in diabetes: a cohort study[J ] . Ann Intern Med, 2009, 151(12): 854-860. DOI: 10.7326/0003-4819-151-12-200912150-00005.
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