联动成像内镜辅助诊断幽门螺杆菌感染的临床价值

刘浏; 林宇轩; 罗夏朋; 沈雁仪; 黄鹤; 贾柳萍; 谢春生

doi:10.16016/j.1000-5404.202011187

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联动成像内镜辅助诊断幽门螺杆菌感染的临床价值

临床医学 | 更新时间：2026-01-09

- 联动成像内镜辅助诊断幽门螺杆菌感染的临床价值
- Clinical value of linked color imaging endoscopy in auxiliary diagnosis of Helicobacter pylori infection
- 第三军医大学学报 2021年43卷第5期页码：446-451
- 作者机构：
- 作者简介：
- 基金信息：
  
  佛山市医学科技攻关项目(2018AB001962)
- DOI：10.16016/j.1000-5404.202011187
  中图分类号：
- 收稿：2020-03-08，
  
  纸质出版：2021-03-15
- 稿件说明：
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刘浏, 林宇轩, 罗夏朋, 等. 联动成像内镜辅助诊断幽门螺杆菌感染的临床价值[J]. 第三军医大学学报, 2021,43(5):446-451.

Liu LIU, Yuxuan LIN, Xiapeng LUO, et al. Clinical value of linked color imaging endoscopy in auxiliary diagnosis of Helicobacter pylori infection[J]. Journal of Third Military Medical University, 2021, 43(5): 446-451.
刘浏, 林宇轩, 罗夏朋, 等. 联动成像内镜辅助诊断幽门螺杆菌感染的临床价值[J]. 第三军医大学学报, 2021,43(5):446-451. DOI： 10.16016/j.1000-5404.202011187.

Liu LIU, Yuxuan LIN, Xiapeng LUO, et al. Clinical value of linked color imaging endoscopy in auxiliary diagnosis of Helicobacter pylori infection[J]. Journal of Third Military Medical University, 2021, 43(5): 446-451. DOI： 10.16016/j.1000-5404.202011187.

摘要

Abstract

Objective

To investigate the diagnostic value of blue laser linked color imaging (LCI) technology in assistance of detecting infection of

Helicobacter pylori

(Hp).

Methods

A total of 120 patients with positive results of

C-urea breath test (

C-UBT) and 120 individuals with negative results admitted to the Nanhai Hospital due to upper digestive tract symptoms during October 2018 and December 2019 were recruited in the study. Then they were further divided into the study subgroup (undergoing gastroscopy using LCI) and control subgroup (white light imaging

WLI)

respectively

with 60 subjects in each subgroup. Their gender

diagnosis under endoscopy

Hp infection by endoscopic evaluation

result of rapid urease experiment (RUT) and immunohistochemical assay were studied and compared among the groups and subgroups.

Results

There were no significant differences in age

gender and proportions of the diseases diagnosed under endoscopy between the study group and control group (

0.05). The positive rates of Hp infection evaluated by LCI combined with RUT and immunohistochemical assay were significant higher than those from the WLI subgroup (positive group: 93.3%

80.0%

90.0%

75.0%; negative group: 27.9%

13.3%

26.7%

11.7%

0.05). For the positive patients with chronic atrophic gastritis (CAG)

they had significantly higher positive rate of RUT assessed by LCI than by WLI (75.0%

30.8%

0.05). Furthermore

they also had obviously higher positive rates when combined with RUT and immunohistochemical assay than only undergoing simple LCI in positive group and subgroup of chronic non-atr

ophic gastritis (CNAG) (

0.05).

Conclusion

Targeted biopsy guided by LCI for RUT or pathological examination can significantly improve the positive rate of Hp detection

especially to the CAG patients. LCI technology can reduce the risk of gastric neoplasm

and is worthy of promotion in clinical practice.

关键词

Keywords

references

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