应用CorVis ST评估不同屈光状态儿童的角膜生物力学特性

李芳; 钟兴武; 杨军; 龙登虹; 林尤青

doi:10.16016/j.1000-5404.202010102

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应用CorVis ST评估不同屈光状态儿童的角膜生物力学特性

临床医学 | 更新时间：2026-01-09

- 应用CorVis ST评估不同屈光状态儿童的角膜生物力学特性
- Corneal visualization Scheimpflug technology evaluates corneal biomechanical properties in children with different refractive states
- 第三军医大学学报 2021年43卷第8期页码：766-771
- 作者机构：
  
  570311 海口，中山大学中山眼科中心海南眼科医院(海南省眼科医院)，海南省眼科学重点实验室
- 作者简介：
  
  [钟兴武，E-mail: xingzh88@126.com ZHONG Xingwu, E-mail: xingzh88@126.com
- 基金信息：
  
  海南省自然科学基金(CXTD011);海南省自然科学基金(817364)
- DOI：10.16016/j.1000-5404.202010102
  中图分类号： R318.01;R339.141;R778.1
- 收稿：2020-10-16，
  
  修回：2021-01-06，
  
  纸质出版：2021-04-30
- 稿件说明：
移动端阅览
李芳, 钟兴武, 杨军, 等. 应用CorVis ST评估不同屈光状态儿童的角膜生物力学特性[J]. 第三军医大学学报, 2021,43(8):766-771.

Fang LI, Xingwu ZHONG, Jun YANG, et al. Corneal visualization Scheimpflug technology evaluates corneal biomechanical properties in children with different refractive states[J]. Journal of Third Military Medical University, 2021, 43(8): 766-771.
李芳, 钟兴武, 杨军, 等. 应用CorVis ST评估不同屈光状态儿童的角膜生物力学特性[J]. 第三军医大学学报, 2021,43(8):766-771. DOI： 10.16016/j.1000-5404.202010102.

Fang LI, Xingwu ZHONG, Jun YANG, et al. Corneal visualization Scheimpflug technology evaluates corneal biomechanical properties in children with different refractive states[J]. Journal of Third Military Medical University, 2021, 43(8): 766-771. DOI： 10.16016/j.1000-5404.202010102.

摘要

目的

应用可视化角膜生物力学分析仪评估近视、远视、正视儿童的角膜生物力学特性。

方法

选取2019年8月至2020年1月就诊于本院近视、远视、正视的儿童123例(191眼)，利用可视化角膜生物力学分析仪、Lenstar 900生物测量仪分别测量角膜生物力学参数、眼轴、角膜曲率等，应用单因素线性相关分析及多因素线性回归分析年龄、等效球镜、眼轴长度、角膜厚度、平均角膜曲率等对角膜生物力学特性的影响。

结果

经多因素线性回归分析，等效球镜与第1次压平时间(

=0.004)呈正相关关系；眼轴与第1次压平长度(

=0.017)、最大压陷时的反向曲率半径(

=0.02)呈正相关关系，与第2次压平时的变形幅度(

0.001)呈负相关关系；中央角膜厚度与第1次压平长度(

0.001)、第1次压平时的变形幅度(

=0.005)、产生最大压陷的时间(

=0.004)呈正相关关系，与第1次压平时间(

=0.041)呈负相关关系。

结论

儿童的角膜生物力学特性可能与其屈光状态相关，较高度数的近视儿童的角膜粘弹性可能较低。

Abstract

Objective

To evaluate the corneal biomechanical parameters in myopic

hypermetropic and emmetropic eyes using corneal visualization Scheimpflug technology (CorVis ST).

Methods

A total of 123 children having 191 myopic

hypermetropic and emmetropic eyes admitted to our hospital from August 2019 to January 2020 were enrolled in this study. Corneal biomechanical parameters

axial length (AL) and corneal curvature were measured using CorVis ST and Lenstar 900 respectively. Univariate linear correlation analysis and multivariate linear regression analysis were used to assess the impacts of age

spherical equivalent (SE)

central corneal thickness (CCT) and mean corneal curvature on corneal biomechanical parameters.

Results

Multivariate linear regression analysis indicated that SE was positively correlated with time at first applanation (A1T

=0.004); AL was positively correlated with A1T (

=0.017) and radius of reverse curvature at the time of highest concavity (HCR

=0.02)

but negatively with deformation amplitude at second applanation (A2DA

0.001); CCT was positively correlated with length at first applanation (A1L

0.001)

A1DA (

=0.005)

time of highest concavity (

=0.004)

but negatively with A1T (

=0.041).

Conclusion

The biomechanical parameters of children may be related with their refractive states. Higher myopic eyes tend to have lower corneal elasticity.

关键词

Keywords

references

BUENO-GIMENO I, ESPAÑA-GREGORI E, GENE-SAMPEDRO A, et al . Relationship among corneal biomechanics, refractive error, and axial length[J ] . Optom Vis Sci, 2014, 91(5): 507-513. DOI: 10.1097/OPX.0000000000000231.

DEL BUEY M A, LAVILLA L, ASCASO F J, et al . Assessment of corneal biomechanical properties and intraocular pressure in myopic Spanish healthy population[J ] . J Ophthalmol, 2014, 2014: 905129. DOI: 10.1155/2014/905129.

WANG W, HE M, HE H, et al . Corneal biomechanical metrics of healthy Chinese adults using Corvis ST[J ] . Cont Lens Anterior Eye, 2017, 40(2): 97-103. DOI: 10.1016/j.clae.2016.12.003.

NEMETH G, HASSAN Z, CSUTAK A, et al . Repeatability of ocular biomechanical data measurements with a Scheimpflug-based noncontact device on normal corneas[J ] . J Refract Surg, 2013, 29(8): 558-563. DOI: 10.3928/1081597x-20130719-06.

HON Y, LAM A K C. Corneal deformation measurement using scheimpflug noncontact tonometry[J]. Optom Vis Sci, 2013, 90(1): e1-e8. DOI: 10.1097/opx.0b013e3182 79eb87.

WU Y, TIAN L, HUANG Y F, et al . In vivo corneal biomechanical properties with corneal visualization scheimpflug technology in Chinese population[J ] . Biomed Res Int, 2016, 2016: 7840284. DOI: 10.1155/2016/7840284..

ASAOKA R, N AKAKURA S, TABUCHI H, et al . The relationship between corvis ST tonometry measured corneal parameters and intraocular pressure, corneal thickness and corneal curvature[J ] . PLoS ONE, 2015, 10(10): e0140385. DOI: 10.1371/journal.pone.0140385.

WANG J Y, LI Y, JIN Y M, et al . Corneal biomechanical properties in myopic eyes measured by a dynamic scheimpflug analyzer[J ] . J Ophthalmol, 2015, 2015: 161869. DOI: 10.1155/2015/161869.

LEE R, CHANG R T, WONG I Y, et al . Assessment of corneal biomechanical parameters in myopes and emmetropes using the Corvis ST[J ] . Clin Exp Optom, 2016, 99(2): 157-162. DOI: 10.1111/cxo.12341.

HE M, DING H, HE H, et al . Corneal biomechanical properties in healthy children measured by corneal visualization scheimpflug technology[J ] . BMC Ophthalmol, 2017, 17(1): 70. DOI: 10.1186/s12886-017-0463-x.

WU W J, DOU R, WANG Y. Comparison of corneal biomechanics between low and high myopic eyes—A meta-analysis[J]. AmJ Ophthalmol, 2019, 207: 419-425. DOI: 10.1016/j.ajo.2019.07.007.

NEMETH G, SZALAI E, HASSAN Z, et al . Corneal biomechanical data and biometric parameters measured with Scheimpflug-based devices on normal corneas[J ] . Int J Ophthalmol, 2017, 10(2): 217-222. DOI: 10.18240/ijo.2017.02.06.

ZHANG Y H, WANG Y, LI L Y, et al . Corneal stiffness and its relationship with other corneal biomechanical and nonbiomechanical parameters in myopic eyes of Chinese patients[J ] . Cornea, 2018, 37(7): 881-885. DOI: 10.1097/ICO.0000000000001605.

ELSHEIKH A, GERAGHTY B, RAMA P, et al . Characterization of age-related variation in corneal biomechanical properties[J ] . J R Soc Interface, 2010, 7(51): 1475-1485. DOI: 10.1098/rsif.2010.0108.

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