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mDIXON-MRA对乳腺癌腋窝淋巴结可切除性的诊断效能
Diagnostic efficacy of modified DIXON magnetic resonance angiography in axillary lymph node resectability for breast cancer patients
- 第三军医大学学报 2021年43卷第6期 页码：541-546
- 作者机构：
- 作者简介：
- 基金信息：
DOI：10.16016/j.1000-5404.202010061
中图分类号：收稿：2020-10-14，
纸质出版：2021-03-30
- 稿件说明：
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谭钰川, 吕发金, 郑伊能, 等. mDIXON-MRA对乳腺癌腋窝淋巴结可切除性的诊断效能[J]. 第三军医大学学报, 2021,43(6):541-546.
Yuchuan TAN, Fajin LYU, Yineng ZHENG, et al. Diagnostic efficacy of modified DIXON magnetic resonance angiography in axillary lymph node resectability for breast cancer patients[J]. Journal of Third Military Medical University, 2021, 43(6): 541-546.
谭钰川, 吕发金, 郑伊能, 等. mDIXON-MRA对乳腺癌腋窝淋巴结可切除性的诊断效能[J]. 第三军医大学学报, 2021,43(6):541-546. DOI： 10.16016/j.1000-5404.202010061.
Yuchuan TAN, Fajin LYU, Yineng ZHENG, et al. Diagnostic efficacy of modified DIXON magnetic resonance angiography in axillary lymph node resectability for breast cancer patients[J]. Journal of Third Military Medical University, 2021, 43(6): 541-546. DOI： 10.16016/j.1000-5404.202010061.
摘要
Abstract
Objective
2
To evaluate the diagnostic efficacy of modified DIXON magnetic resonance angiography (mDIXON-MRA) in the possibility of axillary lymph node dissection for patients with breast cancer.
Methods
2
A retrospective case-control trial was conducted on 77 patients with breast cancer who underwent MRI examination in the Affiliated Tumor Hospital of Chongqing University from December 2018 to January 2020. All the patients preoperatively received mDIXON-MRA
T1 weighted imaging (T1WI)
T2 weighted imaging (T2WI)
fat-suppressed T2-weighted imaging (T2WI-FS)
and contrast-enhanced T1 weighted imaging (T1WI-CE) on the axillary region. After image post-processing and reconstruction
the obtained images were analyzed and scored by 2 radiologists respectively according to the film reviewing criteria. The resectability of lymph nodes was evaluated by judging the relationship between lymph nodes and peripheral blood vessels
and the difference of scoring the images from different sequences was compared and analyzed. Receiver operating characteristic (ROC) curve was plotted based on the intraoperative judgment of the surgeon
and then the effectiveness of different sequences was analyzed in diagnosis of the resectability of enlarged lymph nodes in breast cancer patients.
Results
2
Mean score of the images from mDIXON-MRA
T1WI
T2WI
T2WI-FS and T1WI-CE were 2.01±0.97
2.22±1.05
2.22±1.07
2.42±1.06
and 2.53±1.02
respectively. And significant differences were observed in the diagnostic effectiveness of axillary lymph nodes resectability based on the 5 sequences (
P
<
0.05). The area under the curve (AUC) of mDIXON-MRA sequence took the highest (0.854) among the 5 sequences
which was equivalent to the area after the combination of multiple sequences
showing the best evaluation efficiency.
Conclusion
2
mDIXON-MRA presents the highest clinical diagnostic value among various MRI sequences in the evaluation of the resectability of axillary lymph nodes in breast cancer patients
with its diagnostic efficiency similar to that of combined application of multiple sequences.
关键词
Keywords
references
TORRE L A BRAY F SIEGEL R L Global cancer statistics, 2012 CA Cancer J Clin 2015 65 2 87 108 10.3322/caac.21262 TORRE L A, BRAY F, SIEGEL R L, et al . Global cancer statistics, 2012[J ] . CA Cancer J Clin, 2015, 65(2): 87-108. DOI: 10.3322/caac.21262.
SIEGEL R L MILLER K D JEMAL A Cancer statistics, 2020 CA Cancer J Clin 2020 70 1 7 30 10.3322/caac.21590 SIEGEL R L, MILLER K D, JEMAL A. Cancer statistics, 2020[J]. CA Cancer J Clin, 2020, 70(1): 7-30. DOI: 10.3322/caac.21590.
CHEN W ZHENG R BAADE P D Cancer statistics in China, 2015 CA Cancer J Clin 2016 66 2 115 132 10.3322/caac.21338 CHEN W, ZHENG R, BAADE P D, et al . Cancer statistics in China, 2015[J ] . CA Cancer J Clin, 2016, 66(2): 115-132. DOI: 10.3322/caac.21338.
BONOTTO M GERRATANA L POLETTO E Measures of outcome in metastatic breast cancer: insights from a real-world scenario Oncologist 2014 19 6 608 615 10.1634/theoncologist.2014-0002 BONOTTO M, GERRATANA L, POLETTO E, et al . Measures of outcome in metastatic breast cancer: insights from a real-world scenario[J ] . Oncologist, 2014, 19(6): 608-615. DOI: 10.1634/theoncologist.2014-0002.
DE FELICE C CIPOLLA V STAGNITTI A Diagnostic accuracy of 1.5 Tesla breast magnetic resonance imaging in the pre-operative assessment of axillary lymph nodes Eur J Gynaecol Oncol 2015 36 4 447 451 http://europepmc.org/abstract/med/26390701 DE FELICE C, CIPOLLA V, STAGNITTI A, et al . Diagnostic accuracy of 1.5 Tesla breast magnetic resonance imaging in the pre-operative assessment of axillary lymph nodes[J ] . Eur J Gynaecol Oncol, 2015, 36(4): 447 -451.
杨 亦 姚 钰 刘 家伟 多种影像学手段评估乳腺癌患者腋窝淋巴结状态的对比研究 南京医科大学学报(自然科学版) 2019 39 5 721 726 杨亦, 姚钰, 刘家伟, 等. 多种影像学手段评估乳腺癌患者腋窝淋巴结状态的对比研究[J]. 南京医科大学学报(自然科学版), 2019, 39(5): 721-726.
YANG Y YAO Y LIU J W Comparative study of different imaging methods in evaluating axillary lymph node status in patients with breast cancer J Nanjing Med Univ(Natural Sciences) 2019 39 5 721 726 YANG Y, YAO Y, LIU J W, et al . Comparative study of different imaging methods in evaluating axillary lymph node status in patients with breast cancer[J ] . J Nanjing Med Univ(Natural Sciences), 2019, 39(5): 721-726.
周 之明 钼靶、CT与DCE-MRI评价乳腺癌淋巴结转移的价值 影像研究与医学应用 2019 3 2 83 84 https://www.cnki.com.cn/Article/CJFDTOTAL-YXYY201902056.htm 周之明. 钼靶、CT与DCE-MRI评价乳腺癌淋巴结转移的价值[J]. 影像研究与医学应用, 2019, 3(2): 83-84.
ZHOU Z M Value of mammography, CT and DCE-MRI in evaluating lymph node metastasis of breast cancer J Imaging Res Med Appl 2019 3 2 83 84 https://www.cnki.com.cn/Article/CJFDTOTAL-YXYY201902056.htm ZHOU Z M. Value of mammography, CT and DCE-MRI in evaluating lymph node metastasis of breast cancer[J]. J Imaging Res Med Appl, 2019, 3(2): 83-84.
DUMITRU D KHAN A CATANUTO G Axillary surgery in breast cancer: the beginning of the end Minerva Chir 2018 73 3 314 321 10.23736/s0026-4733.18.07728-3 DUMITRU D, KHAN A, CATANUTO G, et al . Axillary surgery in breast cancer: the beginning of the end[J ] . Minerva Chir, 2018, 73(3): 314-321. DOI: 10.23736/s0026-4733.18.07728-3.
STEPANSKY F HECHT E M RIVERA R Dynamic MR angiography of upper extremity vascular disease: pictorial review Radiographics 2008 28 1 e28 10.1148/radiol.e28 STEPANSKY F, HECHT E M, RIVERA R, et al . Dynamic MR angiography of upper extremity vascular disease: pictorial review[J ] . Radiographics, 2008, 28(1): e28. DOI: 10.1148/radiol.e28.
CONNELL D A KOULOURIS G THORN D A Contrast-enhanced MR angiography of the hand Radiographics 2002 22 3 583 599 10.1148/radiographics.22.3.g02ma16583 CONNELL D A, KOULOURIS G, THORN D A, et al . Contrast-enhanced MR angiography of the hand. [J ] . Radiographics, 2002, 22(3): 583-599. DOI:10.1148/radiographics.22.3.g02ma16583.
DAYAN J H DAYAN E KAGEN A The use of magnetic resonance angiography in vascularized groin lymph node transfer: an anatomic study J Reconstr Microsurg 2014 30 1 41 45 10.1055/s-0033-1351668 DAYAN J H, DAYAN E, KAGEN A, et al . The use of magnetic resonance angiography in vascularized groin lymph node transfer: an anatomic study[J ] . J Reconstr Microsurg, 2014, 30(1): 41-45. DOI: 10.1055/s-0033-1351668.
SADICK M SADICK H HÖRMANN K Cross-sectional imaging combined with 3D-MR angiography (3D-MRA): diagnostic tool for preoperative vascular assessment of head and neck tumors Onkologie 2005 28 10 477 481 10.1159/000087127 SADICK M, SADICK H, HÖRMANN K, et al . Cross-sectional imaging combined with 3D-MR angiography (3D-MRA): diagnostic tool for preoperative vascular assessment of head and neck tumors[J ] . Onkologie, 2005, 28(10): 477-481. DOI: 10.1159/000087127.
DORTCH J , FORTE A J , BOLAN C , et al . Preoperative analysis of venous anatomy before deep inferior epigastric perforator free-flap breast reconstruction using ferumoxytol-enhanced magnetic resonance angiography [J ] . Ann Plast Surg , 2018 , Publish Ahead of Print . DOI: 10.1097/sap.0000000000001421 . DORTCH J, FORTE A J, BOLAN C, et al . Preoperative analysis of venous anatomy before deep inferior epigastric perforator free-flap breast reconstruction using ferumoxytol-enhanced magnetic resonance angiography[J ] . Ann Plast Surg, 2018, Publish Ahead of Print. DOI: 10.1097/sap.0000000000001421.
CORRAL D A VARMA D G JACKSON E F Magnetic resonance imaging and magnetic resonance angiography before postchemotherapy retroperitoneal lymph node dissection Urology 2000 55 2 262 266 10.1016/s0090-4295(99)00428-8 CORRAL D A, VARMA D G, JACKSON E F, et al . Magnetic resonance imaging and magnetic resonance angiography before postchemotherapy retroperitoneal lymph node dissection[J ] . Urology, 2000, 55(2): 262-266. DOI: 10.1016/s0090-4295(99)00428-8.
谭 钰川 吕 发金 乳腺癌淋巴结可切除性的影像学评估研究进展 磁共振成像 2020 11 3 235 237 谭钰川, 吕发金. 乳腺癌淋巴结可切除性的影像学评估研究进展[J]. 磁共振成像, 2020, 11(3): 235-237.
TAN Y C LYU F J Advances in imaging evaluation of lymph node resectability in breast cancer Chin J Magnetic Resonance Imaging 2020 11 3 235 237 TAN Y C, LYU F J. Advances in imaging evaluation of lymph node resectability in breast cancer[J]. Chin J Magnetic Resonance Imaging, 2020, 11(3): 235-237.
HEYNEN B TAMIGNEAUX C PASOGLOU V MRI detection of radiographically occult fractures of the hip and pelvis in the elderly: Comparison of T2-weighted Dixon sequence with T1-weighted and STIR sequences Diagn Interv Imaging 2019 100 3 169 175 10.1016/j.diii.2018.11.008 HEYNEN B, TAMIGNEAUX C, PASOGLOU V, et al . MRI detection of radiographically occult fractures of the hip and pelvis in the elderly: Comparison of T2-weighted Dixon sequence with T1-weighted and STIR sequences[J ] . Diagn Interv Imaging, 2019, 100(3): 169-175. DOI: 10.1016/j.diii.2018.11.008.
KOURTIDOU S JONES M R MOORE R A mDixon ECG-gated 3-dimensional cardiovascular magnetic resonance angiography in patients with congenital cardiovascular disease J Cardiovasc Magn Reson 2019 21 1 52 10.1186/s12968-019-0554-3 KOURTIDOU S, JONES M R, MOORE R A, et al . mDixon ECG-gated 3-dimensional cardiovascular magnetic resonance angiography in patients with congenital cardiovascular disease[J ] . J Cardiovasc Magn Reson, 2019, 21(1): 52. DOI: 10.1186/s12968-019-0554-3.
KIRCHGESNER T PERLEPE V MICHOUX N Fat suppression at three-dimensional T1-weighted MR imaging of the hands: Dixon method versus CHESS technique Diagn Interv Imaging 2018 99 1 23 28 10.1016/j.diii.2017.09.004 KIRCHGESNER T, PERLEPE V, MICHOUX N, et al . Fat suppression at three-dimensional T1-weighted MR imaging of the hands: Dixon method versus CHESS technique[J ] . Diagn Interv Imaging, 2018, 99(1): 23-28. DOI: 1 0.1016/j.diii.2017.09.004.
LEINER T HABETS J VERSLUIS B Subtractionless first-pass single contrast medium dose peripheral MR angiography using two-point Dixon fat suppression Eur Radiol 2013 23 8 2228 2235 10.1007/s00330-013-2833-y LEINER T, HABETS J, VERSLUIS B, et al . Subtractionless first-pass single contrast medium dose peripheral MR angiography using two-point Dixon fat suppression[J ] . Eur Radiol, 2013, 23(8): 2228-2235. DOI: 10.1007/s00330-013-2833-y.
HADIZADEH D R MARX C GIESEKE J High temporal and high spatial resolution MR angiography (4D-MRA) Rofo 2014 186 9 847 859 10.1055/s-0034-1366661 HADIZADEH D R, MARX C, GIESEKE J, et al . High temporal and high spatial resolution MR angiography (4D-MRA)[J ] . Rofo, 2014, 186(9): 847-859. DOI: 10.1055/s-0034-1366661.
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