重庆市主城区2017-2019年环境空气污染对自然流产影响的病例交叉研究

明鑫; 胡雅琼; 杨赟平; 何子翼; 陈红燕; 李燕喃; 周妮娅; 陈卿; 周文正

doi:10.16016/j.1000-5404.202010002

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重庆市主城区2017-2019年环境空气污染对自然流产影响的病例交叉研究

专题报道:生殖损害和不良妊娠结局的危险因素研究 | 更新时间：2026-01-09

- 重庆市主城区2017-2019年环境空气污染对自然流产影响的病例交叉研究
- Effect of environmental air pollution on spontaneous abortion in the main urban area of Chongqing from 2017 to 2019: a case-crossover study
- 第三军医大学学报 2021年43卷第1期页码：25-30
- 作者机构：
- 作者简介：
- 基金信息：
  
  重庆市自然科学基金面上项目(CSTC2020jcyj-msxmX0511);重庆市技术创新与应用示范专项(CSTC2018jscx-mszdX0021)
- DOI：10.16016/j.1000-5404.202010002
  中图分类号：
- 收稿：2020-10-01，
  
  纸质出版：2021-01-15
- 稿件说明：
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明鑫, 胡雅琼, 杨赟平, 等. 重庆市主城区2017-2019年环境空气污染对自然流产影响的病例交叉研究[J]. 第三军医大学学报, 2021,43(1):25-30.

Xin MING, Yaqiong HU, Yunping YANG, et al. Effect of environmental air pollution on spontaneous abortion in the main urban area of Chongqing from 2017 to 2019: a case-crossover study[J]. Journal of Third Military Medical University, 2021, 43(1): 25-30.
明鑫, 胡雅琼, 杨赟平, 等. 重庆市主城区2017-2019年环境空气污染对自然流产影响的病例交叉研究[J]. 第三军医大学学报, 2021,43(1):25-30. DOI： 10.16016/j.1000-5404.202010002.

Xin MING, Yaqiong HU, Yunping YANG, et al. Effect of environmental air pollution on spontaneous abortion in the main urban area of Chongqing from 2017 to 2019: a case-crossover study[J]. Journal of Third Military Medical University, 2021, 43(1): 25-30. DOI： 10.16016/j.1000-5404.202010002.

摘要

Abstract

Objective

To analyze the relationship between air pollutants and spontaneous abortion in Chongqing.

Methods

Time trend bias was controlled by time-stratified case-crossover design. The distribution lag nonlinear model was employed to study the relationship between air pollution and the number of spontaneous abortion in the main urban area of Chongqing and to control the influence of confounding factors such as meteorological factors. Based on the single pollutant model

the two-pollutant model was used to control the influence of other pollutants on correlation.

Results

During the study period

the average daily concentration of PM

2.5

and SO

in the air was 39.32

63.31

41.04 and 8.86μg/m

respectively. All pollutants except NO

were associated with the risk of spontaneous abortion

and all the associations reached the peak value at the lag of 3 d. For the increase of every 10μg/m

the relative risk value was 1.069 (95%

: 1.010~1.132)

1.046 (95%

: 1.007~1.086) and 1.511 (95%

: 1.148~1.989)

respectively. These associations still existed in the two-pollutants model.

Conclusion

Short-term exposure of PM

2.5

and SO

in the ambient air may increase the risk of spontaneous abortion in Chongqing.

关键词

Keywords

references

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