重庆市大学生指长比与男性生殖表型的关联研究

李雪; 何孟超; 王艺蒙; 周妮娅; 杨桓; 敖琳; 刘晋祎; 曹佳; 陈卿

doi:10.16016/j.1000-5404.202009205

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重庆市大学生指长比与男性生殖表型的关联研究

专题报道:生殖损害和不良妊娠结局的危险因素研究 | 更新时间：2026-01-09

- 重庆市大学生指长比与男性生殖表型的关联研究
- Correlation between second to fourth digit ratio and male reproductive phenotypes in college students in Chongqing
- 第三军医大学学报 2021年43卷第1期页码：45-51
- 作者机构：
- 作者简介：
- 基金信息：
  
  国家自然科学基金重点项目(81630087);国家重点研发计划(2017YFC1600200)
- DOI：10.16016/j.1000-5404.202009205
  中图分类号：
- 收稿：2020-09-24，
  
  纸质出版：2021-01-15
- 稿件说明：
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李雪, 何孟超, 王艺蒙, 等. 重庆市大学生指长比与男性生殖表型的关联研究[J]. 第三军医大学学报, 2021,43(1):45-51.

Xue LI, Mengchao HE, Yimeng WANG, et al. Correlation between second to fourth digit ratio and male reproductive phenotypes in college students in Chongqing[J]. Journal of Third Military Medical University, 2021, 43(1): 45-51.
李雪, 何孟超, 王艺蒙, 等. 重庆市大学生指长比与男性生殖表型的关联研究[J]. 第三军医大学学报, 2021,43(1):45-51. DOI： 10.16016/j.1000-5404.202009205.

Xue LI, Mengchao HE, Yimeng WANG, et al. Correlation between second to fourth digit ratio and male reproductive phenotypes in college students in Chongqing[J]. Journal of Third Military Medical University, 2021, 43(1): 45-51. DOI： 10.16016/j.1000-5404.202009205.

摘要

Abstract

Objective

To investigate the association of the ratio of second to fourth digit with adult male reproductive phenotypes in the undergraduates in Chongqing.

Methods

A total of 569 male undergraduates were sampled from our previously established cohort of the male reproductive health in Chongqing college students(MARHCS) study. Their lengths of second and fourth digits in the left hand were measured to calculate the ratio of second to fourth digit. And their anogenital distance

testicular vertical diameters

testicular volume

semen parameters and reproductive hormone levels were measured and detected.

Results

The median digit ratio was 0.97 in the subjects

with 86.29% of them having the ratio ≤1. After adjustment of smoking

drinking

body mass index and abstinence period

a 0.1 increase of digit ratio was associated with 12.5%(95%

: 0.7%~37.3%

=0.033) increase of semen volume

and 87.1%(95%

: 1.3%~819.9%

=0.038) increase of total sperm count. Single factor variance analysis showed that the digit ratio was significantly correlated with the distance of anus center to scrotum posterior base(AS) in (

=0.136

=0.001). When the covariates were controlled

a 0.1 increase of digit ratio was associated with 2.5%(95%

: 0.3%~5.2%

=0.023) increase of the anogenital distance. Compared to the subjects with digit ratio ≤1

those with digit ratio

1 were associated with -10.3%(95%

: -17.6%~-2.5%

=0.012) follicle-stimulating hormone. However

these associations were not statistical significance after multiple-test corre

ction.

Conclusion

Conclusion Digit ratio has no substantial association with adult reproductive phenotypes

including semen parameters and reproductive hormones in the healthy male college students in Chongqing.

关键词

Keywords

references

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