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收稿:2020-09-24,
纸质出版:2021-01-15
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曹佳, 陈卿. 生殖损害和不良妊娠结局的环境、生活方式和心理危险因素研究进展及展望[J]. 第三军医大学学报, 2021,43(1):1-9.
Jia CAO, Qing CHEN. rogress and prospective of environmental, lifestyle and psychological risk factors for reproductive impairment and adverse birth outcome[J]. Journal of Third Military Medical University, 2021, 43(1): 1-9.
曹佳, 陈卿. 生殖损害和不良妊娠结局的环境、生活方式和心理危险因素研究进展及展望[J]. 第三军医大学学报, 2021,43(1):1-9. DOI: 10.16016/j.1000-5404.202009204.
Jia CAO, Qing CHEN. rogress and prospective of environmental, lifestyle and psychological risk factors for reproductive impairment and adverse birth outcome[J]. Journal of Third Military Medical University, 2021, 43(1): 1-9. DOI: 10.16016/j.1000-5404.202009204.
Nowadays
reproductive impairment and adverse birth outcome are eme
rging major health challenges in China. Effective prevention strategies for these problems substantially depend on the identification of the related risk factors in the population and on the understanding of their underlying mechanisms. In this review
we discuss the potential risk factors in environmental
lifestyle and psychological aspects. Besides the further profound understanding of known risk factors
such as environmental endocrine disruptors and heavy metals
the roles and mechanisms of some novel factors
including PM
2.5
circadian disruption and chronic stress
were also unveiled. New knowledge and techniques
especially the findings in the mechanism of reproductive system development and functioning
multi-omics methods
novel toxicity testing strategy and cohort study may provide brand new opportunities and inspirations for future researches on the prevention and treatment of reproductive impairment and adverse birth outcome.
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