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模拟实爆条件下新型聚脲类材料对肺冲击伤的防护效应研究
Bioprotective effects of novel polyurea materials on blast wave in simulated open field explosions
- 第三军医大学学报 2020年42卷第19期 页码：1875-1881
- 作者机构：
- 作者简介：
- 基金信息：国家重点基础研究计划(613307);陆军军医大学（第三军医大学）人才扶持计划(2019);陆军特色医学中心人才创新能力培养计划(2019CXJSA001);陆军特色医学中心人才创新能力培养计划(2019CXJSB007)
DOI：10.16016/j.1000-5404.202003159
中图分类号：收稿：2020-03-13，
纸质出版：2020-10-15
- 稿件说明：
移动端阅览
薛钰奇, 张华才, 文大林, 等. 模拟实爆条件下新型聚脲类材料对肺冲击伤的防护效应研究[J]. 第三军医大学学报, 2020,42(19):1875-1881.
Yuqi Xue, Huacai Zhang, Dalin Wen, et al. Bioprotective effects of novel polyurea materials on blast wave in simulated open field explosions[J]. Journal of Third Military Medical University, 2020, 42(19): 1875-1881.
薛钰奇, 张华才, 文大林, 等. 模拟实爆条件下新型聚脲类材料对肺冲击伤的防护效应研究[J]. 第三军医大学学报, 2020,42(19):1875-1881. DOI： 10.16016/j.1000-5404.202003159.
Yuqi Xue, Huacai Zhang, Dalin Wen, et al. Bioprotective effects of novel polyurea materials on blast wave in simulated open field explosions[J]. Journal of Third Military Medical University, 2020, 42(19): 1875-1881. DOI： 10.16016/j.1000-5404.202003159.
摘要
Abstract
Objective
2
To investigate the protection efficacy of novel polyurea materials concerning their bioprotective effects of lungs and blast mitigation so as to provide the theoretical and material support.
Methods
2
A 7kg TNT explosive ball was used to observe the changes in the peak pressure of shock waves in in a human torso model
covered with a series of polyurea materials at 3.8 m and 5.8 m from the explosion center respectively under open field conditions. The first part of experiment was divided into the ultra-high molecular weight polyethylene (UHWPE
PE) and new polyurea series + PE groups. The new polyurea materials were divided into seven types according to the molecular structure transformation method and volume fractions of micron glass particles: PUR1、PUR1G20、PUR1G30、PUR2、PUR2G20、PUR2G30、PUR3. Each type was tested once at 3.6 m and 3.8 m respectively. In the second part
a typical type of polyurea with good blast mitigation was selected in the bioprotective evaluation and a goat chest mold for anti-blast was prepared. Twenty-four experimental goats were randomly divided into the unprotected
PE
polyurea
and polyurea + PE groups. Based on the estimation of peak pressure of 7kg TNT air explosion
the chest wall acceleration
vital signs
and gross injury levels of lungs in explosions as previously described were observed at 3.6 m and 3.8 m from the explosion center.
Results
2
At 3.8 m and 5.8 m from the explosion center
the attenuation effects of new polyurea group on shock waves were increased by 23% - 35% and 25% - 50%
respectively
compared with the PE group. At 3.6 m and 3.8 m from the explosion center
the chest wall acceleration in the polyurea + PE group was preferably 55.56% and 65.20% lower than that in the unprotected group
respectively. The lung injury was significantly alleviated compared with the PE group
and the injury was reduced by 2 levels.
Conclusion
2
The new polyurea material has ideal protective effects on pulmonary blast injury by attenuating shock waves.
关键词
Keywords
references
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