57例非疫区COVID-19出院患者流行病学及临床特点分析

杨凯; 肖玲燕; 刘永福; 史东阳; 卢虎; 李田田; 郑以山

doi:10.16016/j.1000-5404.202002166

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57例非疫区COVID-19出院患者流行病学及临床特点分析

特别报道：新型冠状病毒病的防控 | 更新时间：2026-01-09

- 57例非疫区COVID-19出院患者流行病学及临床特点分析
- Epidemiological and clinical characteristics of coronavirus disease 2019 in non-epidemic areas: report of 57 cases
- 第三军医大学学报 2020年42卷第6期页码：555-559
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.16016/j.1000-5404.202002166
  中图分类号：
- 收稿：2020-02-24，
  
  纸质出版：2020-03-30
- 稿件说明：
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杨凯, 肖玲燕, 刘永福, 等. 57例非疫区COVID-19出院患者流行病学及临床特点分析[J]. 第三军医大学学报, 2020,42(6):555-559.

Kai YANG, Lingyan XIAO, Yongfu LIU, et al. Epidemiological and clinical characteristics of coronavirus disease 2019 in non-epidemic areas: report of 57 cases[J]. Journal of Third Military Medical University, 2020, 42(6): 555-559.
杨凯, 肖玲燕, 刘永福, 等. 57例非疫区COVID-19出院患者流行病学及临床特点分析[J]. 第三军医大学学报, 2020,42(6):555-559. DOI： 10.16016/j.1000-5404.202002166.

Kai YANG, Lingyan XIAO, Yongfu LIU, et al. Epidemiological and clinical characteristics of coronavirus disease 2019 in non-epidemic areas: report of 57 cases[J]. Journal of Third Military Medical University, 2020, 42(6): 555-559. DOI： 10.16016/j.1000-5404.202002166.

摘要

Abstract

Objective

To investigate the epidemiological and clinical characteristics of coronavirus disease 2019 (COVID-19) in non-endemic areas.

Methods

From January 2020

the Nanjing Public Health Medical Center began to treat confirmed patients. Retrospective analysis was carried out in 57 patients with identified novel coronavirus-infected pneumonia and having been discharged for the epidemiological characteristics

clinical signs and symptoms

laboratory test results

and CT images.

Results

The 57 patients were at an age ranging from 5 to 97 years (median 37 years)

and 29 males (50.9%) and 28 females (49.1%). Among them

35 cases had clear contact with the epidemic area Wuhan

and 16 were clustered cases. The average incubation period was 7.4 d for the disease. In them

54 cases occurred locally

23 patients had fever as the first symptom

and 13 patients had normal temperature. Other main first symptoms included dry cough (14 cases

24.6%) and body aches and fatigue (5 cases

8.8%). The patients with decreased peripheral white blood cell count accounted for 26.3%

those with reduced lymphatic or eosinophils count for 47.4%

those with increased average platelet volume for 24.7%

elevated serum ALT or AST levels for 15.8%

raised CKMB for 5.3%

and those with decreased blood potassium for 40.4%. All patients had lung illness and were positive to nucleic acid test

and 66.7% of them got both lung involved. Of the 57 patients

26.3% were mild and 73.7% were ordinary. Their average length of hospital stay was 10.1 d

and they had an average course of 15.6 d. All of them were treated with interferon αb1 combined with acetylcysteine

47 cases were combined with kriging

and 18 cases with abidol. All the 57 cases were improved and discharged.

Conclusion

All these cases in Najing are almost imported from the epidemic area. The clinical classification is mainly ordinary type. Low fever

dry cough

sore throat and systemic soreness

decreased lymphocytes

ground glass shadow in CT images

and positive to nucleic acids are the main clinical features of the disease.

关键词

Keywords

references

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