如何权衡左心耳封堵术的风险与获益？

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如何权衡左心耳封堵术的风险与获益？

专家述评 | 更新时间：2026-01-09

- 如何权衡左心耳封堵术的风险与获益？
- How to balance the risks and benefits of left atrial appendage closure?
- 第三军医大学学报 2019年41卷第19期页码：1851-1854
- 作者机构：
  
  400038 重庆，陆军军医大学(第三军医大学)第一附属医院心血管内科，重庆市介入心脏病学研究所
- 作者简介：
  
  [宋治远，主任医师, 教授，博士生导师。担任中国医师协会心血管内科分会常委及结构性心脏病专委会副主任委员，中国医师协会介入医师分会常委，中华预防医学会循证预防医学专业委员会常委，重庆市医学会心血管内科专委会副主任委员，重庆市老年学与老年医学学会心血管病分会主任委员。主持国家自然科学基金等科研项目20多项，获得国家科技进步二等奖1项，重庆市科技进步一等奖2项、二等奖2项，华夏医学科技进步二等奖1项。以第一作者或通信作者发表论文200余篇(其中SCI收录50篇)。主要从事心律失常的基础与临床、结构性心脏病介入治疗方面的研究。E-mail: zysong2010@126.comSONG Zhiyuan, E-mail: zysong2010@126.com
- 基金信息：
  
  重庆市社会事业与民生保障科技专项(CSTC2016shms-ztzx10001-3)
- DOI：10.16016/j.1000-5404.201908074
  中图分类号： R541.75;R619
- 收稿：2019-08-12，
  
  修回：2019-09-02，
  
  纸质出版：2019-10-15
- 稿件说明：
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宋治远. 如何权衡左心耳封堵术的风险与获益？[J]. 第三军医大学学报, 2019,41(19):1851-1854.

Zhiyuan SONG. How to balance the risks and benefits of left atrial appendage closure?[J]. Journal of Third Military Medical University, 2019, 41(19): 1851-1854.
宋治远. 如何权衡左心耳封堵术的风险与获益？[J]. 第三军医大学学报, 2019,41(19):1851-1854. DOI： 10.16016/j.1000-5404.201908074.

Zhiyuan SONG. How to balance the risks and benefits of left atrial appendage closure?[J]. Journal of Third Military Medical University, 2019, 41(19): 1851-1854. DOI： 10.16016/j.1000-5404.201908074.

摘要

左心耳封堵术(left atrial appendage closure

LAAC)是预防非瓣膜性房颤(non-valvular atrial fibrillation

NVAF)患者缺血性卒中的新技术，其临床疗效与安全性已被公认，并被国内外相关指南推荐。然而，LAAC的临床获益与风险并存，如何权衡LAAC的风险与获益是当今临床关注的重要问题之一。本述评从多中心临床随机对照研究入手，较系统地阐述了LAAC在预防NVAF患者缺血性卒中方面的循证医学证据；并对LAAC并发症的发生率及主要并发症进行了叙述；提出了“降低风险、增加获益”的具体举措。

Abstract

Left atrial appendage closure (LAAC) is a new technique to prevent ischemic stroke in patients with non-valvular atrial fibrillation (NVAF)

and recommended by international and domestic guidelines due to its confirmed efficacy and safety in clinical practice. However

its benefits have always been coexisting with some risks. So

how to balance the risks and benefits is one of the important issues concerned by clinical professionals. Based on randomized clinical trials

this manuscript systematically introduces the evidence-based medicine of LAAC in preventing ischemic stroke with NVAF patients

elucidates incidence of complications and major complications of LAAC

then puts forward specific measurement of reducing risks and increasing benefits in clinical practice.

关键词

Keywords

references

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