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400016 重庆,重庆医科大学附属第一医院泌尿外科
[唐伟,主任医师,教授,博士生导师。担任中华医学会泌尿外科分会委员,全国结石学组委员,国际结石联盟委员,亚洲男科学会常务委员,中国医师协会全国男科医师分会常务委员,男科培训委员会副主任委员,中国泌尿男科医学技术与装备创新联盟委员,中国男性健康联盟全国常务委员,中国医药教育协会泌尿外科专委会委员,重庆市医学会男科学专委会主任委员。主持并参与国家自然科学基金及省部级课题19项,已发表包括SCI收录在内的论文147篇,参编3部专著,获省部级科技成果奖3项,国家级发明专利1项。主要从事泌尿系肿瘤及泌尿系结石方面的研究。E-mail:tangwei2060@163.comTANG Wei, E-mail: tangwei2060@163.com
收稿:2019-05-29,
修回:2019-09-01,
纸质出版:2019-10-15
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唐伟, 胡代星. 干细胞在男性不育领域的应用及展望[J]. 第三军医大学学报, 2019,41(19):1897-1901.
Wei TANG, Daixing HU. Application and progress of stem cells in male infertility[J]. Journal of Third Military Medical University, 2019, 41(19): 1897-1901.
唐伟, 胡代星. 干细胞在男性不育领域的应用及展望[J]. 第三军医大学学报, 2019,41(19):1897-1901. DOI: 10.16016/j.1000-5404.201905188.
Wei TANG, Daixing HU. Application and progress of stem cells in male infertility[J]. Journal of Third Military Medical University, 2019, 41(19): 1897-1901. DOI: 10.16016/j.1000-5404.201905188.
目前干细胞已成为医学研究的热点,并逐渐从基础研究向临床应用方面转化。多种干细胞在男性不育领域的研究已取得较多进展,如精原干细胞(spermatagonial stem cells,SSCs)、间充质干细胞(mesenchymal stem cells,MSCs)、胚胎干细胞(embryonic stem cells,ESCs)和诱导多潜能干细胞(induced pluripotent stem cells,iPSCs),但仍然存在一些问题和挑战,如安全性、有效性、伦理、法律、市场监管等诸多方面。现就干细胞在男性不育领域的相关研究和进展进行评述,为干细胞更合理地应用于男性不育治疗提供参考。
Researches concerning stem cells have made great progresses
and become a hot spot in medical sciences
which has gradually transformed from basic research to clinical application. Many types of stem cells were used in male infertility
including spermatogonia stem cells (SSCs)
mesenchymal stem cells (MSCs)
embryonic stem cells (ESCs)
and induced pluripotent stem cells (iPSCs). However
there are still some problems and challenges
such as safety
effectiveness
ethics
law
market regulation and other aspects. This article reviews the research and progress of stem cells
and provides reference for the application of stem cells more rationally in the field of male infertility.
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