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一种具有双通道恒定泄气量功能的无创正压通气面罩研制及应用效果评价
Development and efficiency of a noninvasive positive pressure ventilation
via face mask with 2 channels and constant leakage- 第三军医大学学报 2020年42卷第4期 页码：421-426
- 作者机构：
1.400016 重庆，重庆医科大学:附属第一医院重症医学科
2.400016 重庆，重庆医科大学:生物医学工程学院
3.400010 重庆，重庆医科大学附属第二医院老年科
- 作者简介：
[徐钦，E-mail: 1295056703@qq.com XU Qin, E-mail: 1295056703@qq.com
- 基金信息：重庆市科卫联合医学科研项目(2019MSXM002)
DOI：10.16016/j.1000-5404.201905009
中图分类号： R197.39; R605.973收稿：2019-05-05，
修回：2019-07-08，
纸质出版：2020-02-28
- 稿件说明：
移动端阅览
黄桃, 王华, 徐钦. 一种具有双通道恒定泄气量功能的无创正压通气面罩研制及应用效果评价[J]. 第三军医大学学报, 2020,42(4):421-426.
Tao HUANG, Hua WANG, Qin XU. Development and efficiency of a noninvasive positive pressure ventilation
via face mask with 2 channels and constant leakage[J]. Journal of Third Military Medical University, 2020, 42(4): 421-426.黄桃, 王华, 徐钦. 一种具有双通道恒定泄气量功能的无创正压通气面罩研制及应用效果评价[J]. 第三军医大学学报, 2020,42(4):421-426. DOI： 10.16016/j.1000-5404.201905009.
Tao HUANG, Hua WANG, Qin XU. Development and efficiency of a noninvasive positive pressure ventilation
via face mask with 2 channels and constant leakage[J]. Journal of Third Military Medical University, 2020, 42(4): 421-426. DOI： 10.16016/j.1000-5404.201905009.
摘要
目的
2
探讨一种具有双通道恒定泄气量功能(two channels and constant leakage，TCCL)的无创正压通气(noninvasive positive pressure ventilation，NPPV)面罩研制及应用效果。
方法
2
完成TCCL面罩的发明设计、三维构建和产品制造。利用24例健康人进行NPPV试验，根据不同的NPPV面罩类型，按随机数字表法分为2组:研究组采用TCCL面罩；对照组采用普通型NPPV面罩。标准化实验条件下，呼气气道正压(expiratory positive airway pressure
EPAP)为5、10 cmH
2
O时，监测两组面罩内呼气末二氧化碳分压(pressure of end-tidal carbon dioxide，PetCO
2
)变化；测试呼吸机吸入气体氧气浓度(FiO
2
)分别为30%、50%，且吸气气道正压(inspiratory positive airway pressure
IPAP)分别为10、20 cmH
2
O时，监测面罩内FiO
2
变化。
结果
2
标准化试验条件下，相同EPAP水平(5 cmH
2
O或10 cmH
2
O)时，研究组面罩内PetCO
2
均显著低于对照组(
P
<
0.05)；相同FiO
2
水平(FiO
2
为30%或50%)及IPAP为10、20 cmH
2
O时，两组组内及组间面罩内FiO
2
比较差异均无统计学意义。
结论
2
TCCL面罩对面罩内CO
2
的清除效果优于普通型NPPV面罩且不影响吸入气体O
2
浓度。
Abstract
Objective
2
To explore the preparation and efficiency of a positive pressure ventilation (NPPV)
via
face mask with 2 channels and constant leakage function (TCCL).
Methods
2
The NPPV-TCCL
via
face mask was invented
designed
three-
dimensionally constructed and manufactured by our team. Twenty-four healthy individuals were recruited and randomly divided into the test group and the control group to wear our produced NPPV-TCCL
via
face mask and conventional NPPV via face mask
respectively. Under standard experimental conditions with expiratory positive airway pressure (EPAP) of 5 and 10 cmH
2
O
the pressure of end-tidal carbon dioxide (PetCO
2
) was monitored in the mask. The inspired oxygen fraction (FiO
2
) was monitored in the mask when the FiO
2
parameters of the ventilator were set to 30% and 50%
and inspiratory positive airway pressure (IPAP) was 10 and 20 cmH
2
O respectively.
Results
2
Under standard experimental conditions and at the same level of EPAP (5 or 10 cmH
2
O)
the PetCO
2
in the mask was significantly lower in the test group than the control group (all
P
<
0.05). At the same level of FiO
2
(30% or 50%) and IPAP=10 or 20cmH
2
O
there was no significant difference in FiO
2
between the 2 groups (
P
>
0.05).
Conclusion
2
NPPV-TCCL
via
face mask is superior to conventional NPPV mask in eliminating CO
2
and having no effect on FiO
2
.
关键词
Keywords
references
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