2型糖尿病患者肌少症的相关因素分析

陈成; 张巧; 钟芳

doi:10.16016/j.1000-5404.201902032

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2型糖尿病患者肌少症的相关因素分析

临床医学 | 更新时间：2026-01-09

- 2型糖尿病患者肌少症的相关因素分析
- Relative factors to sarcopenia in type 2 diabetes patients
- 第三军医大学学报 2019年41卷第15期页码：1468-1472
- 作者机构：
- 作者简介：
- 基金信息：
  
  贵州省优秀科技人才省长专项资金项目(黔省专合字[(2010)82号])
- DOI：10.16016/j.1000-5404.201902032
  中图分类号：
- 收稿：2019-02-05，
  
  纸质出版：2019-08-15
- 稿件说明：
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陈成, 张巧, 钟芳. 2型糖尿病患者肌少症的相关因素分析[J]. 第三军医大学学报, 2019,41(15):1468-1472.

Cheng CHEN, Qiao ZHANG, Fang ZHONG. Relative factors to sarcopenia in type 2 diabetes patients[J]. Journal of Third Military Medical University, 2019, 41(15): 1468-1472.
陈成, 张巧, 钟芳. 2型糖尿病患者肌少症的相关因素分析[J]. 第三军医大学学报, 2019,41(15):1468-1472. DOI： 10.16016/j.1000-5404.201902032.

Cheng CHEN, Qiao ZHANG, Fang ZHONG. Relative factors to sarcopenia in type 2 diabetes patients[J]. Journal of Third Military Medical University, 2019, 41(15): 1468-1472. DOI： 10.16016/j.1000-5404.201902032.

摘要

Abstract

Objective

To investigate the occurrence of sarcopenia in the patients with type 2 diabetes mellitus (T2DM) and the relationship of its related factors.

Methods

Cross-sectional survey was adopted to select 450 T2DM patients (256 males and 194 females) who were hospitalized in the Department of Endocrinology and Metabolism of Affiliated Hospital of Guizhou Medical University from April 2015 to November 2015. Their general conditions

blood indexes

and body composition indexes were investigated. According to the diagnostic criteria of the Asian Working Group on Sarcopenia

sarcopenia was diagnosed with relative skeletal muscle mass index (RASM) described as appendicular muscle mass divided by height square

with male

7.00 kg/m

and female

5.40 kg/m

Results

There were 64 patients suffering from sarcopenia

with a total prevalence rate of 14.22%. The prevalence rate of males and females was 19.14% and 7.73%

respectively (

0.05). The age was older and creatinine level was higher in the sarcopenia group than the non-sarcopenia group (

0.05). The body mass index (BMI)

android/gynoid (A/G) fat ratio and triglyceride level were significantly lower in the sarcopenia group compared with the non-sarcopenia group (

0.05). M

ultivariate logistic regression analysis showed that after correcting confounding factors including age and gender

smoking (

=2.156

95%

: 1.226~3.790) was a risk factor

while BMI (

=0.529

95%

: 0.448~0.625) and A/G fat ratio (

=0.007

95%

: 0.001~0.046) were protective factors for sarcopenia.

Conclusion

Smoking is a risk factor for sarcopenia in type 2 diabetic patients. BMI and A/G fat ratio may be protective factors for sarcopenia.

关键词

Keywords

references

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