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收稿:2019-01-29,
纸质出版:2019-08-15
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李景铧, 张帆, 张毅, 等. 全腔镜与开放手术治疗cT1N0甲状腺乳头状癌的临床对比研究[J]. 第三军医大学学报, 2019,41(15):1461-1467.
Jinghua LI, Fan ZHANG, Yi ZHANG, et al. Clinical comparison of total endoscopy and open thyroidectomy for cT1N0 thyroid papillary carcinoma[J]. Journal of Third Military Medical University, 2019, 41(15): 1461-1467.
李景铧, 张帆, 张毅, 等. 全腔镜与开放手术治疗cT1N0甲状腺乳头状癌的临床对比研究[J]. 第三军医大学学报, 2019,41(15):1461-1467. DOI: 10.16016/j.1000-5404.201901227.
Jinghua LI, Fan ZHANG, Yi ZHANG, et al. Clinical comparison of total endoscopy and open thyroidectomy for cT1N0 thyroid papillary carcinoma[J]. Journal of Third Military Medical University, 2019, 41(15): 1461-1467. DOI: 10.16016/j.1000-5404.201901227.
Objective
2
To explore the feasibility of totally endoscopic thyroidectomy (TET) for thyroid papillary carcinoma in cT
1
N
0
stage.
Methods
2
Clinical data of 287 patients with primary cT
1
N
0
thyroid papillary cancer underwent thyroidectomy in our hospital from March 2016 to June 2018 were collected and retrospectively analyzed
including 145 patients undergoing TET (TET group) and 142 patients by open thyroidectomy (OT group). The intraoperative conditions
complications
recurrence and cosmetic effect were compared between the 2 groups.
Results
2
There were no significant differences in the general data of the patients in the TET group and OT group
inclu
ding mean age (
P
=0.283)
sex ratio (
P
=0.344)
tumor size (
P
=0.265) and tumor distribution (
P
=0.872). In terms of surgical effects
no significant differences were observed in the numbers of central neck lymph node dissections (CNLN) (
P
=0.847) and metastatic lymph nodes (
P
=0.839) between the 2 groups for the patients with lateral lobectomy and lateral central neck dissection. The TET group had significantly smaller volume of intraoperative bleeding (
P
<
0.001)
and longer operation time (
P
<
0.001) when compared with the OT group. For those with bilateral lobectomy and lateral central neck dissection
there were no significant differences in the numbers of central neck lymph node dissections (
P
=0.092) and metastatic lymph nodes (
P
=0.241) between the 2 groups. The amount of intraoperative bleeding was smaller (
P
<
0.001) and the operation time were longer in the TET group (
P
<
0.001) than the OT group. For surgical complications
there were no significant differences in the incidences of temporary/permanent hyperparathyroidism and recurrent laryngeal nerve injury between the 2 group (
P
>
0.05). No hemorrhagic subcutaneous fluid or wound infection occurred in the TET group. The TET group had significantly better cosmetic effect than the OT group (
P
<
0.001). The patients were followed up for 6 to 30 months
and no recurrence was observed.
Conclusion
2
TET treatment is safe and feasible for cT1N0 thyroid papillary cancer. TET treatment might be an optional approach for the patients with cosmetic demand.
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