主动脉内球囊反搏在心脏瓣膜手术中应用时机选择的病例对照研究

霍永凤; 王学锋; 陈林; 王咏; 肖颖彬

doi:10.16016/j.1000-5404.201808043

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主动脉内球囊反搏在心脏瓣膜手术中应用时机选择的病例对照研究

临床医学 | 更新时间：2026-01-09

- 主动脉内球囊反搏在心脏瓣膜手术中应用时机选择的病例对照研究
- Timing of intra-aortic balloon pump for valve replacement patients: a case-control trial
- 第三军医大学学报 2018年40卷第21期页码：1991-1995
- 作者机构：
- 作者简介：
- 基金信息：
  
  军队临床高新技术重大项目(2010gxjs069)
- DOI：10.16016/j.1000-5404.201808043
  中图分类号：
- 收稿：2018-08-09，
  
  纸质出版：2018-11-15
- 稿件说明：
移动端阅览
霍永凤, 王学锋, 陈林, 等. 主动脉内球囊反搏在心脏瓣膜手术中应用时机选择的病例对照研究[J]. 第三军医大学学报, 2018,40(21):1991-1995.

Yongfeng HUO, Xuefeng WANG, Lin CHEN, et al. Timing of intra-aortic balloon pump for valve replacement patients: a case-control trial[J]. Journal of Third Military Medical University, 2018, 40(21): 1991-1995.
霍永凤, 王学锋, 陈林, 等. 主动脉内球囊反搏在心脏瓣膜手术中应用时机选择的病例对照研究[J]. 第三军医大学学报, 2018,40(21):1991-1995. DOI： 10.16016/j.1000-5404.201808043.

Yongfeng HUO, Xuefeng WANG, Lin CHEN, et al. Timing of intra-aortic balloon pump for valve replacement patients: a case-control trial[J]. Journal of Third Military Medical University, 2018, 40(21): 1991-1995. DOI： 10.16016/j.1000-5404.201808043.

摘要

Abstract

Objective

To optimize the timing of intra-aortic balloon pump (IABP) in its perioperative application for patients undergoing heart valve surgery.

Methods

Clinical data of 98 patients who undergoing IABP during perioperative period of valve replacement surgery in our department from January 2015 to December 2017 were collected and retrospectively analyzed. After 20 patients were excluded due to death

the left patients were assigned to preventive implantation group (

=34) and postoperative implantation group (

=44)

according to the time of IABP implantation. Their general data

heart function

intra- and post-operative lactic acid (Lac)

mean arterial pressure (MAP)

urine volume and pH value were compared between the 2 groups for the efficacy of IABP timing.

Results

There were no statistical differences in general data between the 2 group before surgery. The preven

tive implantation group had stable Lac

pH value and MAP in the early stage after surgery. Compared with the postoperative implantation group

the preventive implantation group had poorer heart function (serum brain natriuretic peptide

1 172.18±1 301.02

727.54± 835.53 pg/dL

=0.014)

but shorter utilization time of invasive ventilator (727.54±835.53

85.18±62.60 h

=0.001) and length of ICU stay (5.62±1.67

8.05±3.27 h

0.001). In the cohort

there were 2 cases died during operation and 18 cases died after operation (including 7 cases of malignant arrhythmia

2 cases of severe pulmonary infection

4 cases of multiple organ failure and 5 cases of refractory low cardiac output).

Conclusion

IABP effectively prevents low cardiac output syndrome in the perioperative period of valve surgery. Preventive implantation of IABP will reduce the incidence of postoperative complications and improve early heart function recovery in the patients with giant left ventricle and lower left ventricular ejection.

关键词

Keywords

references

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