356例非透析慢性肾衰竭患者抑郁情况及生命质量的分析研究

熊利; 伍亚舟; 牟庆云; 邓莉; 周洪文; 肖耀俊; 刘秀梅; 蒲敏

doi:10.16016/j.1000-5404.201808033

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356例非透析慢性肾衰竭患者抑郁情况及生命质量的分析研究

公共卫生与预防医学 | 更新时间：2026-01-09

- 356例非透析慢性肾衰竭患者抑郁情况及生命质量的分析研究
- epression and quality of life in non-dialysis patients with chronic renal failure: analysis of 356 cases
- 第三军医大学学报 2019年41卷第2期页码：163-169
- 作者机构：
  
  1.400038 重庆，陆军军医大学(第三军医大学)军事预防医学系军队卫生统计学教研室
  2.404500 重庆，重庆市云阳县人民医院病案统计科
  3.404100 重庆，重庆市三峡中心医院肾病内科
  4.405200 重庆，重庆市梁平区人民医院：肾病内科
  5.405200 重庆，重庆市梁平区人民医院：病案统计科
  6.402260 重庆，重庆市江津区中医院病案室
- 作者简介：
  
  [ 伍亚舟，E-mail: asiawu@tmmu.edu.cn WU Yazhou, E-mail: asiawu@tmmu.edu.cn
- 基金信息：
  
  国家自然科学基金面上项目(81573254);国家自然科学基金面上项目(81273178)
- DOI：10.16016/j.1000-5404.201808033
  中图分类号： R181.23;R692.5;R749.4
- 收稿：2018-08-06，
  
  修回：2018-10-09，
  
  纸质出版：2019-01-30
- 稿件说明：
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熊利, 伍亚舟, 牟庆云, 等. 356例非透析慢性肾衰竭患者抑郁情况及生命质量的分析研究[J]. 第三军医大学学报, 2019,41(2):163-169.

Li XIONG, Yazhou WU, Qingyun MU, et al. epression and quality of life in non-dialysis patients with chronic renal failure: analysis of 356 cases[J]. Journal of Third Military Medical University, 2019, 41(2): 163-169.
熊利, 伍亚舟, 牟庆云, 等. 356例非透析慢性肾衰竭患者抑郁情况及生命质量的分析研究[J]. 第三军医大学学报, 2019,41(2):163-169. DOI： 10.16016/j.1000-5404.201808033.

Li XIONG, Yazhou WU, Qingyun MU, et al. epression and quality of life in non-dialysis patients with chronic renal failure: analysis of 356 cases[J]. Journal of Third Military Medical University, 2019, 41(2): 163-169. DOI： 10.16016/j.1000-5404.201808033.

摘要

目的

评估非透析慢性肾衰竭患者的抑郁情况和生命质量

分析二者的相关关系及其影响因素。

方法

选取2017年5月至2018年3月在重庆市三峡中心医院、重庆市云阳县人民医院、重庆市梁平区人民医院、重庆市江津区中医院就诊的并明确诊断为慢性肾衰竭且没有进行过透析的356例患者; 采用Beck抑郁量表评估患者的抑郁情况

慢性肾衰竭生命质量量表(QLICD-CRF2.0)评估患者的生命质量情况。

结果

356例非透析慢性肾衰竭患者抑郁发生率为45.22%;生命质量方面

抑郁组患者生理功能、心理功能、社会功能的评分均低于非抑郁组; 反映症状的特异性模块的评分高于非抑郁组(

均

0.05);抑郁情况与生命质量的二分类Logistic回归分析结果显示:职业(

=1.753

95%

: 1.352~2.273)、住院次数(

=1.221

95%

: 1.007~1.480)、体现症状体征的特异性模块(

=1.034

95%

: 1.011~1.058)、心理功能(

=0.922

95%

: 0.902~0.942)、教育状况(

=0.597

95%

: 0.394~0.906)、家庭人均年收入(

=0.514

95%

: 0.346~0.765)是抑郁发生的独立危险因素。

结论

非透析慢性肾衰竭患者的抑郁发生率较高

抑郁组患者的生命质量低于非抑郁组

职业、住院次数、特异性模块、心理功能、教育状况和家庭人均年收入影响着非透析慢性肾衰竭患者的生命质量。

Abstract

Objective

To evaluate the prevalence of depression and quality of life and their correlation in non-dialysis patients with chronic renal failure and analyze the factors affecting the occurrence of depression in these patients.

Methods

This study was conducted among 356 non-dialysis patients with chronic renal failure (including both inpatients and outpatients) from 4 general hospitals in Chongqing during the period from May

2017 to March

2018. Beck Depression Inventory-Ⅱ (BDI-Ⅱ) was used to assess the patient's depression

and the quality of life the patients was assessed using Quality of Life Instrument for Chronic Disease-Chronic Renal Failure (QLICD-CRF2.0).

Results

The incidence of depression was 45.22% in the 356 patients with chronic renal failure without dialysis. The patients with depression had significantly lower quality of life scores (including the physiological function

psychological function

social function and total scores)

but had significantly higher scores in the specific modules of response symptoms than those without depression (

0.05). Binary logistic regression analysis of depression and quality of life showed that occupation (

=1.753

95%

: 1.352-2.273)

hospitalization frequency (

=1.221

95%

: 1.007-1.480)

specific modules (

=1.034

95%

: 1.011-1.058)

psychological function (

=0.922

95%

: 0.902-0.942)

education level (

=0.597

95%

: 0.394-0.906)

and annual income of the family (

=0.514

95%

: 0.346-0.765) were all independent risk factors for the occurrence of de

pression in these patients.

Conclusion

The incidence of depression is high in non-dialysis patients with chronic renal failure. The patients with depression have lower quality of life scores than those without depression. Occupation

hospitalization frequency

specific modules

psychological function

education level and annual income of the family may affect the quality of life among the non-dialysis patients.

关键词

Keywords

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