两种不同时间口服聚乙二醇对小肠胶囊内镜肠道准备效果影响的多中心随机对照研究

杨强强; 邓涛; 徐红; 彭学; 杨雪丽; 金国花; 赵晓晏

doi:10.16016/j.1000-5404.201807219

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两种不同时间口服聚乙二醇对小肠胶囊内镜肠道准备效果影响的多中心随机对照研究

临床医学 | 更新时间：2026-01-09

- 两种不同时间口服聚乙二醇对小肠胶囊内镜肠道准备效果影响的多中心随机对照研究
- Clinical efficacy of 2 schedules of oral polyethylene glycol solution for bowel preparations before small bowel capsule endoscopy: a multicenter, randomized controlled study
- 第三军医大学学报 2018年40卷第21期页码：1973-1977
- 作者机构：
- 作者简介：
- 基金信息：
  
  国家卫计委公益性行业科研专项(201502013)
- DOI：10.16016/j.1000-5404.201807219
  中图分类号：
- 收稿：2018-07-31，
  
  纸质出版：2018-11-15
- 稿件说明：
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杨强强, 邓涛, 徐红, 等. 两种不同时间口服聚乙二醇对小肠胶囊内镜肠道准备效果影响的多中心随机对照研究[J]. 第三军医大学学报, 2018,40(21):1973-1977.

Qiangqiang YANG, Tao DENG, Hong XU, et al. Clinical efficacy of 2 schedules of oral polyethylene glycol solution for bowel preparations before small bowel capsule endoscopy: a multicenter, randomized controlled study[J]. Journal of Third Military Medical University, 2018, 40(21): 1973-1977.
杨强强, 邓涛, 徐红, 等. 两种不同时间口服聚乙二醇对小肠胶囊内镜肠道准备效果影响的多中心随机对照研究[J]. 第三军医大学学报, 2018,40(21):1973-1977. DOI： 10.16016/j.1000-5404.201807219.

Qiangqiang YANG, Tao DENG, Hong XU, et al. Clinical efficacy of 2 schedules of oral polyethylene glycol solution for bowel preparations before small bowel capsule endoscopy: a multicenter, randomized controlled study[J]. Journal of Third Military Medical University, 2018, 40(21): 1973-1977. DOI： 10.16016/j.1000-5404.201807219.

摘要

Abstract

Objective

To compare the intestinal preparation efficacy of taking 2 L polyethylene glycol (PEG) solution in 2 and 4 h before small bowel capsule endoscopy (SBCE) in order to explore the optimal time.

Methods

A multicenter

randomized controlled trial was conducted in 3 hospital during January 2016 and June 2018. According to our inclusion and exclusion criteria

totally 160 patients were enrolled

and then randomly assigned into 2 groups at a ratio of 1 :1 and given a schedule of oral administration of 2 L PEG in 4 or 6 h before SBCE

respectively. The main evaluation indexes were the excellent rate of small bowel visualization quality (SBVQ)

and the secondary ones included diagnostic yield

complete rate of total small intestine

gastric transit time

and small bowel transit time.

Results

The 4 h group obtained significantly higher excellent rate of SBVQ [(65.8±17.4)%

(59.3±17.3)%

=0.034

]

and shorter small bowel transit time (269.1±115.3

313.9±104.7 min

=0.019) when compared with the 6 h group. What's more

the diagnostic yield

complete rate of total small intestine and gastric transit time were 70.1% (54/77)

86.7%(66/77) and 38.0(19.0~89.5) min respectively in the 4 h group

and were 68.4%(54/79)

89.9%(71/79) and 28.5(11.7~50.5) min in the 6 h group

but there were no statistical differences between the 2 groups (

0.05).

Conclusion

The 2 schedules of taking 2 L PEG solution before SBCE have no significant effects on diagnostic yield

complete rate of total small intestine and gastric transit time

but the 4 h scheme presents better SBVQ.

关键词

Keywords

references

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