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18F-FDG PET/CT在淋巴瘤及淋巴结结核诊断中的价值
Value of 18F-FDG PET/CT in diagnosis of lymphoma and lymph node tuberculosis
- 第三军医大学学报 2018年40卷第17期 页码：1599-1604
- 作者机构：
- 作者简介：
- 基金信息：
DOI：10.16016/j.1000-5404.201803029
中图分类号：收稿：2018-03-05，
纸质出版：2018-09-15
- 稿件说明：
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张雨涵, 冉淑华, 罗为, 等. 18F-FDG PET/CT在淋巴瘤及淋巴结结核诊断中的价值[J]. 第三军医大学学报, 2018,40(17):1599-1604.
Yuhan ZHANG, Shuhua RAN, Wei LUO, et al. Value of 18F-FDG PET/CT in diagnosis of lymphoma and lymph node tuberculosis[J]. Journal of Third Military Medical University, 2018, 40(17): 1599-1604.
张雨涵, 冉淑华, 罗为, 等. 18F-FDG PET/CT在淋巴瘤及淋巴结结核诊断中的价值[J]. 第三军医大学学报, 2018,40(17):1599-1604. DOI： 10.16016/j.1000-5404.201803029.
Yuhan ZHANG, Shuhua RAN, Wei LUO, et al. Value of 18F-FDG PET/CT in diagnosis of lymphoma and lymph node tuberculosis[J]. Journal of Third Military Medical University, 2018, 40(17): 1599-1604. DOI： 10.16016/j.1000-5404.201803029.
摘要
Abstract
Objective
2
To evaluate the value of
18
F-FDG PET/CT in diagnosis of lymphoma and lymph node tuberculosis by observing the findings in order to improve the diagnostic accuracy.
Methods
2
18
F-FDG PET/CT findings of 51 patients with pathologically diagnosed lymphomas or lymph node tuberculosis who had undergone the
18
F-FDG PET/CT scanning between September 2015 and September 2017 in our hospital were collected and retrospectively analyzed. The distribution
shape
size
and
18
F-FDG take-up were evaluated and analyzed.
Results
2
The 41 cases of lymphoma and 10 cases of lymph node tuberculosis presented as integration lesions (16 and 0 case)
calcified mediastinal lymph nodes (1 and 5 cases) and circular intake (1 and 0 case)
and combined with pulmonary tuberculosis (0 and 1 case). The diagnostic accuracy of
18
F-FDG PET and CT was 100% and 50% respectively.
18
F-FDG PET/CT findings for the 2 diseases were systemic ly
mph node enlargement (18 and 1 cases)
local lymph node enlargement (23 and 9 cases)
splenic involvement or higher
18
F-FDG take-up (14 and 2 cases)
bone involved or higher
18
F-FDG take-up (6 and 1 case)
both spleen and bone involved (4 and 0 case). For the lymphoma patients
the average size and average SUVmax value of lymph node was 30.42±14.03 mm and 13.40±7.56; while was 18.59±6.56 mm and 7.66±3.32 for lymph node tuberculosis patients. Significant difference were seen in the diameter and SUVmax value between the 2 groups of patients (
P
<
0.05). When the cutoff SUVmax value was 2.5
the sensitivity and specificity was 100% and 0%~10%
respectively in the diagnosis of lymphoma. According to the ROC curve
when the cutoff of SUVmax value was 9.725
the sensitivity and specificity was 65.9% and 80.0%
respectively.
Conclusion
2
There are similar findings in clinical manifestations and
18
F-FDG PET/CT images between lymphoma and lymph node tuberculosis
but the value of the examination is higher for diagnosis of the former
while lower for the latter. Increase of the cutoff SUVmax value and combination the size of lymph nodes can provide certain help to the differential diagnosis in a certain extent.
关键词
Keywords
references
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