院前预警对缩短急性缺血性卒中患者就诊到溶栓时间的影响

王英; 吴娅; 赵秋菊; 马雪; 李玮

doi:10.16016/j.1000-5404.201801237

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院前预警对缩短急性缺血性卒中患者就诊到溶栓时间的影响

临床医学 | 更新时间：2026-01-09

- 院前预警对缩短急性缺血性卒中患者就诊到溶栓时间的影响
- Prenotification for thrombolysis before admission shortens door-to-needle time for patients with acute ischemic stroke
- 第三军医大学学报 2018年40卷第16期页码：1523-封3
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.16016/j.1000-5404.201801237
  中图分类号：
- 收稿：2018-01-30，
  
  纸质出版：2018-08-30
- 稿件说明：
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王英, 吴娅, 赵秋菊, 等. 院前预警对缩短急性缺血性卒中患者就诊到溶栓时间的影响[J]. 第三军医大学学报, 2018,40(16):1523-封3.

Ying WANG, Ya WU, Qiuju ZHAO, et al. Prenotification for thrombolysis before admission shortens door-to-needle time for patients with acute ischemic stroke[J]. Journal of Third Military Medical University, 2018, 40(16): 1523-封3.
王英, 吴娅, 赵秋菊, 等. 院前预警对缩短急性缺血性卒中患者就诊到溶栓时间的影响[J]. 第三军医大学学报, 2018,40(16):1523-封3. DOI： 10.16016/j.1000-5404.201801237.

Ying WANG, Ya WU, Qiuju ZHAO, et al. Prenotification for thrombolysis before admission shortens door-to-needle time for patients with acute ischemic stroke[J]. Journal of Third Military Medical University, 2018, 40(16): 1523-封3. DOI： 10.16016/j.1000-5404.201801237.

摘要

Abstract

Objective

To evaluate the effect of prenotification before admission for thrombolysis in shortening the door-to-needle time (DNT) and on the outcomes of patients with acute ischemic stroke.

Methods

This retrospective analysis was conducted based on the data of 115 patients with acute ischemic stroke receiving intravenous thrombolytic treatment in our stroke center between June

2016 and June

2017.The difference in the DNT was analyzed between patients with prenotification for thrombolysis before admission (

=40) and those without prenotification (

=75).The onset-to-needle time (ONT)

National Institutes of Health Stroke Scale (NHISS) score at discharge

the rate of good prognosis (mRS score 0 to 2) and the mortality rate at 90 days were also re

corded and analyzed.

Results

The ONT was slightly longer in the prenotification group than in the group without prenotificaiton (207.00±89.71

175.11±65.21 min

=0.031)

but the DNT was significantly shorter in the prenotification group (42.57±19.58

59.55±13.95 min

0.01).No significant difference was found between the 2 groups in NHISS scores at discharge

the rate of good prognosis or the mortality rate at 90 d (

0.05).Compared with the patients without prenotificaiton

the patients with prenotification had significantly shorter door-to-imaging time (

0.05) and the interval from the imaging report to consent by the patients' relatives to thrombolysis (

0.01).The duration of the imaging examination and the time from consent to thrombolysis to the start of thrombolysis therapy were similar between the 2 groups (

0.05).

Conclusion

Prenotification for thrombolysis before admission can shorten the DNT for patients with acute ischemic stroke.In the primary care centers where thrombolytic therapy is not accessible

prenotification of the hospital to which the patient is to be transferred can be essential.

关键词

Keywords

references

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