浏览全部资源
扫码关注微信
盐阈值与冠心病病变严重程度的相关性研究
Correlation between salt taste threshold and severity of coronary heart disease
- 第三军医大学学报 2018年40卷第11期 页码：1044-1047
- 作者机构：
- 作者简介：
- 基金信息：
DOI：10.16016/j.1000-5404.201801156
中图分类号：收稿：2018-01-18，
纸质出版：2018-06-15
- 稿件说明：
移动端阅览
马文莲, 陶贵惠, 杨小利, 等. 盐阈值与冠心病病变严重程度的相关性研究[J]. 第三军医大学学报, 2018,40(11):1044-1047.
Wenlian MA, Guihui TAO, Xiaoli YANG, et al. Correlation between salt taste threshold and severity of coronary heart disease[J]. Journal of Third Military Medical University, 2018, 40(11): 1044-1047.
马文莲, 陶贵惠, 杨小利, 等. 盐阈值与冠心病病变严重程度的相关性研究[J]. 第三军医大学学报, 2018,40(11):1044-1047. DOI： 10.16016/j.1000-5404.201801156.
Wenlian MA, Guihui TAO, Xiaoli YANG, et al. Correlation between salt taste threshold and severity of coronary heart disease[J]. Journal of Third Military Medical University, 2018, 40(11): 1044-1047. DOI： 10.16016/j.1000-5404.201801156.
摘要
Abstract
Objective
2
To investigate the correlation between salt taste threshold and severity of coronary heart disease.
Methods
2
A cross-section study was performed on 198 patients with coronary heart disease diagnosed by coronary angiography admitted in the Third Affiliated Hospital of Army Medical University from October 2017 to January 2018. Another sex- and age-matched 193 patients without coronary artery stenosis by coronary angiography served as control group. According to the number of coronary lesion
the patients of the coronary heart disease group was further divided into single branch lesion
double branch lesion and triple branch lesion subgroups. And based on Gensini score
the severity of coronary lesion was evaluated. The patients' salt taste threshold was determined by using NaCl solution. The differences of salt taste threshold among the above groups were compared
and the correlation between salt taste threshold and severity of coronary heart disease was analyzed.
Results
2
The salt taste threshold was significantly higher in the coronary heart disease group than the control group [(0.75±0.21)%
vs
(0.59±0.18)%
P
<
0.05
]
. With the increase of diseased arteries
the threshold was elevated. After adjustment of traditional risk factors of coronary heart disease using logistic regression model
elevated salt taste threshold was found to increase the prevalence of coronary heart disease (
OR
=3.012
P
<
0.05). Salt taste threshold was positively correlated with the severity of coronary artery disease (Gensini score
r
=0.623
P
<
0.05).
Conclusion
2
Elevated salt taste threshold is a risk factor for coronary heart disease
and it is also positively correlated with the severity of the disease.
关键词
Keywords
references
FAZELI MOGHADAM E TADEVOSYAN A FALLAHI E Nutritional factors and metabolic variables in relation to the risk of coronary heart disease: A case control study in Armenian adults Diabetes Metab Syndr 2017 11 1 7 11 10.1016/j.dsx.2016.06.013 http://cn.bing.com/academic/profile?id=b226fdb0c8cd01f3f9b20fd77f4816a8&encoded=0&v=paper_preview&mkt=zh-cn FAZELI MOGHADAM E, TADEVOSYAN A, FALLAHI E, et al . Nutritional factors and metabolic variables in relation to the risk of coronary heart disease: A case control study in Armenian adults[J ] . Diabetes Metab Syndr, 2017, 11(1):7-11. DOI:10.1016/j.dsx.2016.06.013.
GHISI G L M CHAVES G S D S BRITTO R R Health literacy and coronary artery disease: A systematic review Patient Educ Couns 2017 101 2018 177 184 http://cn.bing.com/academic/profile?id=67da117a13abbbebcc13ac51446c440f&encoded=0&v=paper_preview&mkt=zh-cn GHISI G L M, CHAVES G S D S, BRITTO R R, et al . Health literacy and coronary artery disease: A systematic review [J ] . Patient Educ Couns, 2017, 101(2018):177-184. DOI:10.1016/j.pec.2017.09.002.
YU H LI D CHU X Coronary heart disease: incidence, risk factors and interventions in Jiaozhou of Shandong province Chin Med J(Engl) 2014 127 12 2275 2278 https://www.researchgate.net/publication/263131277_Coronary_heart_disease_Incidence_risk_factors_and_interventions_in_Jiaozhou_of_Shandong_province YU H, LI D, CHU X, et al . Coronary heart disease: incidence, risk factors and interventions in Jiaozhou of Shandong province [J ] . Chin Med J(Engl), 2014, 127(12):2275-2278.
VIJAYVERGIYA R KAPOOR D AGGARWAL A Analysis of traditional and emerging risk factors in premenopausal women with coronary artery disease:A pilot-scale study from North India Mol Cell Biochem 2017 432 1/2 67 78 http://cn.bing.com/academic/profile?id=64dc5c56988efae5b2a220a70a2ff02d&encoded=0&v=paper_preview&mkt=zh-cn VIJAYVERGIYA R, KAPOOR D, AGGARWAL A, et al . Analysis of traditional and emerging risk factors in premenopausal women with coronary artery disease:A pilot-scale study from North India [J ] . Mol Cell Biochem, 2017, 432(1/2):67-78. DOI:10.1007/s11010-017-2998-9.
CHERAGHI M SHAHSAVARI G MALEKI A Para-oxonase 1 activity, lipid profile, and atherogenic indexes status in coronary heart disease Rep Biochem Mol Biol 2017 6 1 1 7 CHERAGHI M, SHAHSAVARI G, MALEKI A, et al . Para-oxonase 1 activity, lipid profile, and atherogenic indexes status in coronary heart disease[J ] . Rep Biochem Mol Biol, 2017, 6(1):1-7.
GHADERI F ESHRAGHI A SHAMLOO A S Assosiation of epicardial and pericardial fat thickness with coronary artery disease Electron Physician 2016 8 9 2982 2989 10.19082/2982 http://cn.bing.com/academic/profile?id=01be2994ae5e9af347af8984e1de9d7c&encoded=0&v=paper_preview&mkt=zh-cn GHADERI F, ESHRAGHI A, SHAMLOO A S, et al . Assosiation of epicardial and pericardial fat thickness with coronary artery disease[J ] . Electron Physician, 2016, 8(9):2982-2989.
KIM C Y YE M K LEE Y S The salt-taste threshold in untreated hypertensive patients Clin Hypertens 2017 23 22 10.1186/s40885-017-0079-8 http://cn.bing.com/academic/profile?id=efdbd80926041bfd44dd46b7124e6689&encoded=0&v=paper_preview&mkt=zh-cn KIM C Y, YE M K, LEE Y S. The salt-taste threshold in untreated hypertensive patients[J]. Clin Hypertens, 2017, 23:22. DOI:10.1186/s40885-017-0079-8.
DEVERE R Disorders of taste and smell Continuum (Minneap Minn) 2017 23 2 421 446 https://emedicine.medscape.com/article/861242-overview DEVERE R. Disorders of taste and smell[J]. Continuum (Minneap Minn), 2017, 23(2):421-446. DOI: 10.1212/CON.0000000000000463.
COHEN J WAKEFIELD C E LAING D G Smell and taste disorders resulting from cancer and chemotherapy Curr Pharm Des 2016 22 15 2253 2263 10.2174/1381612822666160216150812 http://cn.bing.com/academic/profile?id=dad1a233cfe7ff9e8ab9620eb9c15a44&encoded=0&v=paper_preview&mkt=zh-cn COHEN J, WAKEFIELD C E, LAING D G. Smell and taste disorders resulting from cancer and chemotherapy[J]. Curr Pharm Des, 2016, 22(15):2253-2263.
BASSON M D BARTOSHUK L M DICHELLO S Z Association between 6-n-propylthiouracil(PROP) bitterness and colonic neoplasms Dig Dis Sci 2005 50 3 483 489 10.1007/s10620-005-2462-7 https://rd.springer.com/content/pdf/10.1007%2Fs10620-005-2462-7.pdf BASSON M D, BARTOSHUK L M, DICHELLO S Z, et al . Association between 6-n-propylthiouracil(PROP) bitterness and colonic neoplasms [J ] . Dig Dis Sci, 2005, 50(3): 483-489.
KIM T H KIM Y H BAE N Y Salty taste thresholds and preference in patients with chronic kidney disease according to disease stage:A cross-sectional study Nutr Diet 2018 75 1 59 64 10.1111/ndi.2018.75.issue-1 http://cn.bing.com/academic/profile?id=119a8f2711667aec8dfa35ef15722502&encoded=0&v=paper_preview&mkt=zh-cn KIM T H, KIM Y H, BAE N Y, et al . Salty taste thresholds and preference in patients with chronic kidney disease according to disease stage:A cross-sectional study[J ] . Nutr Diet, 2018, 75(1):59-64. DOI: 10.1111/1747-0080.
LIU Z TANG Z ZHANG K Q Salty food preference is associated with osteoporosis among Chinese men Asia Pac J Clin Nutr 2016 25 4 871 878 http://apjcn.nhri.org.tw/server/APJCN/25/4/871.pdf LIU Z, TANG Z, ZHANG K Q, et al . Salty food preference is associated with osteoporosis among Chinese men[J ] . Asia Pac J Clin Nutr, 2016, 25(4):871-878. DOI:10.6133/apjcn.102015.06.
ROURA E FOSTER S WINKLEBACH A Taste and hypertension in humans:targeting cardiovascular disease Curr Pharm Des 2016 22 15 2290 2305 10.2174/1381612822666160216151545 http://cn.bing.com/academic/profile?id=a84fa4dee2f28beeb4118abdd2572c64&encoded=0&v=paper_preview&mkt=zh-cn ROURA E, FOSTER S, WINKLEBACH A, et al . Taste and hypertension in humans:targeting cardiovascular disease[J ] . Curr Pharm Des, 2016, 22(15):2290-2305.
MIZUTA E Impact of taste sensitivity on lifestyle-related diseases Yakugaku Zasshi 2015 135 6 789 792 10.1248/yakushi.14-00250-5 https://www.researchgate.net/publication/277560034_Impact_of_Taste_Sensitivity_on_Lifestyle-related_Diseases MIZUTA E. Impact of taste sensitivity on lifestyle-related diseases[J]. Yakugaku Zasshi, 2015, 135(6):789-792. DOI:10.1248/yakushi.14-00250-5.
UOTA M OGAWA T IKEBE K Factors related to taste sensitivity in elderly: cross-sectional findings from SONIC study J Oral Rehabil 2016 43 12 943 952 10.1111/joor.2016.43.issue-12 http://cn.bing.com/academic/profile?id=96b9caa4d20e11e119752a013d3240a7&encoded=0&v=paper_preview&mkt=zh-cn UOTA M, OGAWA T, IKEBE K, et al . Factors related to taste sensitivity in elderly: cross-sectional findings from SONIC study [J ] . J Oral Rehabil, 2016, 43(12):943-952. DOI: 10.1111/joor.12442.
ZUMKLEY H VETTER H MANDELKOW T Taste sensitivity for sodium chloride in hypotensive, normotensive and hypertensive subjects Nephron 1987 47 1 132 134 10.1159/000184571 http://cn.bing.com/academic/profile?id=1e902d196c7f1aa03568addae6ccf532&encoded=0&v=paper_preview&mkt=zh-cn ZUMKLEY H, VETTER H, MANDELKOW T, et al . Taste sensitivity for sodium chloride in hypotensive, normotensive and hypertensive subjects[J ] . Nephron, 1987, 47(1):132-134.
LI Q JIN R YU H Enhancement of Neural Salty Preference in Obesity Cell Physiol Biochem 2017 43 5 1987 2000 10.1159/000484122 http://europepmc.org/abstract/MED/29055956 LI Q, JIN R, YU H, et al . Enhancement of Neural Salty Preference in Obesity[J ] . Cell Physiol Biochem, 2017, 43(5):1987-2000. DOI:10.1159/000484122.
HUANG Z HUANF S CONG H Smell and taste dysfunction is associated with higher serum total cholesterol concentrations in Chinese adults J Nutr 2017 147 8 1546 1551 10.3945/jn.117.250480 https://www.researchgate.net/publication/317603825_Smell_and_Taste_Dysfunction_Is_Associated_with_Higher_Serum_Total_Cholesterol_Concentrations_in_Chinese_Adults HUANG Z, HUANF S, CONG H, et al . Smell and taste dysfunction is associated with higher serum total cholesterol concentrations in Chinese adults[J ] . J Nutr, 2017, 147(8):1546-1551. DOI:10.3945/jn.117.250480.
DUFFY V B Associations between oral sensation, dietary behaviors and risk of cardiovascular disease(CVD) Appetite 2004 43 1 5 9 10.1016/j.appet.2004.02.007 http://cn.bing.com/academic/profile?id=ba6376f6ee51b19bf0cf6f9aa2b9457c&encoded=0&v=paper_preview&mkt=zh-cn DUFFY V B. Associations between oral sensation, dietary behaviors and risk of cardiovascular disease(CVD)[J]. Appetite, 2004, 43(1):5-9.
0
浏览量
0
下载量
0
CSCD
- Meta-XML下载
- BibTeX下载
- Endnote下载
- RefMan 下载
- NoteExpress下载
- NoteFirst下载
关联资源
相关文章
相关作者
相关机构
- 技术支持由北京北大方正电子有限公司提供 京ICP备09064830号-19
京公网安备11010802024621 - 本系统建议在Chrome、 IE9+ 以上版本浏览器阅读本站内容，360浏览器请切换至极速模式
- Cookies帮助我们提供服务并提供个性化体验。使用本网站，即表示您同意我们使用Cookies
