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多模态影像神经导航联合术中超声在切除颅内胶质瘤中的应用
Clinical value of multimodal image guided neuronavigation combined with intraoperative ultrasound in resection of intracranial gliomas: report of 42 cases
- 第三军医大学学报 2018年40卷第7期 页码：620-624
- 作者机构：
1.050051 石家庄，河北省人民医院：肿瘤二科
2.050051 石家庄，河北省人民医院：神经外二科
- 作者简介：
[郭韬, E-mail：8888guotao@sina.com GUO Tao, E-mail: 8888guotao@sina.com
- 基金信息：河北省科技计划项目(162777209);河北省科技成果推广课题(20170248)
DOI：10.16016/j.1000-5404.201710214
中图分类号： R445;R730.56;R739.41收稿：2017-10-30，
修回：2018-01-10，
纸质出版：2018-04-15
- 稿件说明：
移动端阅览
岳向勇, 武江, 郭韬. 多模态影像神经导航联合术中超声在切除颅内胶质瘤中的应用[J]. 第三军医大学学报, 2018,40(7):620-624.
Xiangyong YUE, Jiang WU, Tao GUO. Clinical value of multimodal image guided neuronavigation combined with intraoperative ultrasound in resection of intracranial gliomas: report of 42 cases[J]. Journal of Third Military Medical University, 2018, 40(7): 620-624.
岳向勇, 武江, 郭韬. 多模态影像神经导航联合术中超声在切除颅内胶质瘤中的应用[J]. 第三军医大学学报, 2018,40(7):620-624. DOI： 10.16016/j.1000-5404.201710214.
Xiangyong YUE, Jiang WU, Tao GUO. Clinical value of multimodal image guided neuronavigation combined with intraoperative ultrasound in resection of intracranial gliomas: report of 42 cases[J]. Journal of Third Military Medical University, 2018, 40(7): 620-624. DOI： 10.16016/j.1000-5404.201710214.
摘要
目的
2
探讨多模态影像神经导航联合术中超声在切除颅内胶质瘤中的临床应用及其价值。
方法
2
回顾性分析本院2007年12月31日至2014年6月30日在多模态影像神经导航联合术中超声辅助下手术治疗的42例颅内胶质瘤患者临床资料，对比手术前后胶质瘤切除程度及胶质瘤继发癫痫的控制情况。
结果
2
全部患者术后无血肿、感染、偏瘫。术后48 h复查MRI，结果显示肿瘤全切除34例，大部切除8例。术后1年评估癫痫控制情况，Engel’s Ⅰ级17例，Engel’s Ⅱ级11例，Engel’s Ⅲ级5例。在保护神经功能的同时，切除肿瘤，控制癫痫发作，临床效果显著。
结论
2
多模态影像神经导航联合术中超声可以实现最大程度切除肿瘤及致痫灶，降低术后神经功能障碍的发生率。
Abstract
Objective
2
To investigate the clinical value of multimodal neuronavigation combined with intraoperative ultrasound in the resection of intracranial gliomas.
Methods
2
A retrospective analysis was carried out on 42 patients undergoing intracranial glioma surgery in our hospital from December 31st
2007 to June 30th 2014 with the aid of multimodal neuronavigation combined with intraoperative ultrasound. Their clinical data were collected and compared before and after surgery
and the resection of glioma and control of glioma-associated epilepsy were investigated.
Results
2
No hematoma
infection or hemiplegia occurred in all the patients. At 48 h after operation
MRI and MRI showed complete resection in 34 cases and subtotal resection in 8 cases. In 1 year after operation
17 case obtained Engel's class Ⅰ
11 cases Engel's class Ⅱ
and 5 cases Engel's class Ⅲ in the evaluation of seizure control. This approach had significant clinical value in protection of nerve function
resection of tumor
and control of epileptic seizure.
Conclusion
2
Multimodal neuroimaging combined with intraoperative ultrasound is helpful to make maximum resection of tumor and epileptic focus and to reduce the incidence of postoperative neurological dysfunction.
关键词
Keywords
references
SELBEKK T, JAKOLA A S, SOLHEIM O, et al . Ultrasound imaging in neurosurgery: approaches to minimize surgically induced image artefacts for improved resection control[J ] . ACTA Neurochir, 2013, 155(6): 973-980. DOI:10.1007/s00701-013-1647-7.
《中国中枢神经系统胶质瘤诊断和治疗指南》编写组.中国中枢神经系统胶质瘤诊断与治疗指南(2015)[J].中华医学杂志, 2016, 96(7): 485-509. DOI:10.3760/cma.j.issn.0376-2491.2016.07.003.
China Central Nervous System Glioma Diagnosis And Treatment Guideline Writing Group. China central nervous system glioma diagnosis and treatment guideline (2015)[J]. Nat Med J China, 2016, 96(7): 485 -509. DOI:10.3760/cma.j.issn.0376-2491.2016.07.003.
COENEN V A, KRINGS T, WEIDEMANN J, et al . Sequential visualization of brain and fiber tract deformation during intracranial surgery with three-dimensional ultrasound: an approach to evaluate the effect of brain shift[J ] . Neurosurgery, 2005, 56(1 Suppl): 133-141. DOI:10.1227/01.neu.0000144315.35094.5f.
RENNER C, LINDNER D, SCHNEIDER J P, et al . Evaluation of intra-operative ultrasound imaging in brain tumor resection: a prospective study[J ] . Neurol Res, 2005, 27(4): 351-357. DOI:10.1179/016164105X40039.
YAMADA H, FUJIMATSU T, SUZUKI H, et al . Surgical excision of left atrial myxoma shortly after cerebral embolism; report of a case[J ] . Kyobu Geka, 2015, 68(3): 221-223.
UNSGAARD G, OMMEDAL S, MULLER T, et al . Neuronavigation by intraoperative three-dimensional ultrasound: initial experience during brain tumor resection[J ] . Neurosurgery, 2002, 50(4 ): 804-812.
COBURGER J, MERKEL A, SCHERER M, et al . Low-grade glioma surgery in intraoperative magnetic resonance imaging: results of a multicenter retrospective assessment of the german study group for intraoperative magnetic resonance imaging[J ] . Neurosurgery, 2016, 78(6): 775-786. DOI:10.1227/NEU.0000000000001081.
KANNO S, TOMIZAWA A, HIURA T, et al . Inhibitory effects of naringenin on tumor growth in human cancer cell lines and sarcoma S-180-implanted mice[J ] . Biol Pharm Bull, 2005, 28(3): 527-530. DOI:10.1248/bpb.28.527.
WOYDT M, PEREZ J, MEIXENSBERGER J, et al . Intra-operative colour-duplex-sonography in the surgical management of cerebral AV-malformations[J ] . Acta Neurochir (Wien), 1998, 140(7): 689-698. DOI:10.1007/s007010050164.
LIN J, JANDIAL R, NESBIT A, et al . Current and emerging treatments for brain metastases[J ] . Oncology (Williston Park, NY), 2015, 29(4): 250-257.
葛亚娟, 杨磊, 高军喜, 等.术中超声造影定量分析在诊断不同级别胶质瘤瘤体及瘤周水肿的临床价值[J].中国超声医学杂志, 2015, 31(3): 193-196.
GE Y J, YANG L, GAO J X, et al . The clinical value of quantitative analysis of contrast-enhanced ultrasonography in the diagnosis of different grades of glioma in tumor and peritumoral edema[J ] . Chin J Ultrasound Med, 2015, 31(3): 193-196.
贺焱, 何文, 杜丽娟, 等.术中超声造影评价脑胶质瘤病理分级及瘤周水肿[J].中华超声影像学杂志, 2011, 20(12): 1036-1039. DOI:10.3760/cma.j.issn.1004-4477.2011.12.008.
HE Y, HE W, DU L J, et al . Intraoperative contrast-enhanced ultrasonic imaging in the evaluation of pathologic grades of cerebral gliomas and peritumoral cerebral edema[J ] . Chin J Ultrasonograph, 2011, 20(12): 1036-1039. DOI:10.3760/cma.j.issn.1004-4477.2011.12.008.
王佳, 段云友, 刘禧, 等.术中超声引导脑胶质瘤手术对患者生存时间的评价[J].中华超声影像学杂志, 2013, 22(11): 941-944. DOI:10.3760/cma.j.issn.1004-4477.2013.11.007.
WANG J, DUAN Y Y, LIU X, et al . Evaluation of intra-operative ultrasonography-guided cerebral glioma surgery on long-term follow-up results of patients[J ] . Chin J Ultrasonograph, 2013, 22(11): 941-944. DOI:10.3760/cma.j.issn.1004-4477.2013.11.007.
郭韬, 刘倩薇, 陈尧, 等.脑磁图联合弥散张量成像在常规磁共振成像阴性的额叶局灶性皮质发育不良术前评估中的应用价值[J].中国全科医学, 2015, 18(6): 729-732. DOI:10.3969/j.issn.1007-9572.2015.06.030.
GUO T, LIU Q W, CHEN Y, et al . Values of combined application of magnetoencephalography and diffusion tensor imaging in the preoperative evaluation o f mri-negative frontal focal cortical dysplasia[J ] . Chin Gen Prac, 2015, 18(6): 729-732. DOI:10.3969/j.issn.1007-9572.2015.06.030.
郭韬, 梁传栋, 吴玉锦, 等.脑磁图联合DTI对大脑半球萎缩继发癫痫患者术前功能区评估的价值[J].中华神经医学杂志, 2014, 13(9): 919-924. DOI:10.3760/cma.j.issn.1671-8925.2014.09.012.
GUO T, LIANG C D, WU Y J, et al . Preoperative functional assessment of epilepsy patients secondary to cerebral hemisphere atrophy by magnetoencephalogram and diffusion tensor imaging[J ] . Chin J Neuromed, 2014, 13(9): 919-924. DOI:10.3760/cma.j.issn.1671-8925.2014.09.012.
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