
浏览全部资源
扫码关注微信
400038 重庆,第三军医大学西南医院妇产科
[ 王丹, E-mail: wangd717@sina.com WANG Dan, E-mail: wangd717@sina.com
收稿:2017-07-20,
修回:2017-09-03,
纸质出版:2017-11-30
移动端阅览
廖媛, 严小丽, 王丹. 128例胎盘早剥患者临床特点分析[J]. 第三军医大学学报, 2017,39(22):2238-2242.
Yuan LIAO, Xiaoli YAN, Dan WANG. Analysis of clinical characteristics of 128 patients with placental abruption[J]. Journal of Third Military Medical University, 2017, 39(22): 2238-2242.
廖媛, 严小丽, 王丹. 128例胎盘早剥患者临床特点分析[J]. 第三军医大学学报, 2017,39(22):2238-2242. DOI: 10.16016/j.1000-5404.201707141.
Yuan LIAO, Xiaoli YAN, Dan WANG. Analysis of clinical characteristics of 128 patients with placental abruption[J]. Journal of Third Military Medical University, 2017, 39(22): 2238-2242. DOI: 10.16016/j.1000-5404.201707141.
目的
2
分析胎盘早剥患者的发病特点及临床结局。
方法
2
回顾性分析本院2014-2016年入院治疗的胎盘早剥患者临床资料,比较院内、院外发病患者的临床特征。
结果
2
纳入128例胎盘早剥患者,其中院内发病者73例,院外发病者55例。胎盘早剥患者中已临产46例(35.9%),未临产82例(64.1%);分娩孕周≥37周62例(48.4%),
<
34周37例(28.9%),未分娩3例(2.3%);剖宫产分娩79例(61.7%),顺产转剖宫产19例(14.8%),顺产23例(17.9%),产钳助产3例(2.3%)。院外发病的患者具有典型临床症状的占96.4%,最易出现的症状为阴道流血(
P
<
0.01)。院内发病患者主要症状表现为胎心率异常(
P
<
0.05)。院外发病患者常因起病急、病情重,紧急剖宫产的比例更高(
P
<
0.01);但在不同发病地点,其发生母儿不良结局(包括胎盘剥离面积、产后出血、死胎等)的风险差异无统计学意义。
结论
2
胎盘早剥部分病例起病隐匿,大多数无特异性表现;院外发病者起病急、病情凶险,及时转诊并进行积极处理后可有效地降低母儿不良结局的发生。
Objective
2
To analyze the clinical characteristics and outcomes of placental abruption.
Methods
2
A retrospective analysis of the clinical data was conducted among patients with placental abruption treated in Southwest Hospital between January 2014 and December 2016. The clinical characteristics were compared between the patients with in-hospital occurrence of placental abruption and those with occurrence before admission.
Results
2
Among the 128 cases of placental abruption treated in our hospital
placental abruption occurred during hospitalization in 73 cases and before admission in 55 cases. Placental abruption occurred during labor in 46 (35.9%) and before labor in 82 (64.1%) of the patients. Upon delivery
62(48.4%) patients were at a gestational age of ≥ 37 weeks and 37 (28.9%) had a gestational age of
<
34 weeks; 3 (2.3%) patients received further expectant treatment without immediate delivery. Seventy-nine (61.7%) of the patients had cesarean delivery
19 (14.8%) had conversion from vaginal delivery to cesarean section
23 (17.9%) had vaginal delivery
and 3 (2.3%) underwent assisted
delivery. Typical clinical symptoms were observed in 96.4% patients with placental abruption before admission
and the most frequent symptom was vaginal bleeding (
P
<
0.01). In patients with occurrence of placental abruption during hospitalization
fetal heart rate abnormality was the most frequent presentation (
P
<
0.05). The patients with placental abruption before admission often had acute onset
critical conditions
and a high likeliness of emergency cesarean section
but they had comparable risks for unfavorable maternal or neonatal outcomes (including extensive placental lesion
postpartum hemorrhage
stillbirth
etc.) with the patients with in-hospital occurrence of placental abruption.
Conclusion
2
In some cases placental abruption occurs without specific manifestations
and nearly half of the patients with placental abruption before admission have acute onset and are in critical condition
who required timely referral and active treatments to lower the risk of unfavorable maternal or neonatal outcomes.
HLADKY K, YANKOWITZ J, HANSEN W F. Placental abruption[J]. Obstet Gynecol Surv, 2002, 57(5): 299-305. DOI: 10.1097/00006254-200205000-00022.
曹泽毅.中华妇产科学[M].北京:人民卫生出版社, 2005: 426-430.
CAO Z Y. Chinese Obstetrics and Gynecology [M]. Beijing:People's Health Publishing House, 2005: 426-430.
QIU C, SANCHEZ S E, GELAYE B, et al . Maternal sleep duration and complaints of vital exhaustion during pregnancy is associated with placental abruption[J ] . J Matern Fetal Neonatal Med, 2015, 28(3): 350-355. DOI: 10.3109/14767058.2014.916682.
中华医学会妇产科学分会产科学组.胎盘早剥的临床诊断与处理规范(第1版)[J].中华妇产科杂志, 2012, 47(12): 957-958. DOI: 10.3760/cma.j.issn.0529-567x.2012.12.022.
Obstetrics and Gynecology Section of Chinese Medical Association. Clinical diagnosis and treatment of placental abruption (first edition) [J]. Chin J Obstet Gynecol, 2012, 47(12): 957-958. DOI: 10.3760/cma.j.issn.0529-567x.2012.12.022.
MACHEKU G S, PHILEMON R N, ONEKO O, et al . Frequency, risk factors and feto-maternal outcomes of abruptio placentae in Northern Tanzania: a registry-based retrospective cohort study[J ] . BMC Pregnancy Childbirth, 2015, 15(1): 242. DOI: 10.1186/s12884-015-0678-x.
ABRAMOVICI A, GANDLEY R E, CLIFTON R G, et al . Prenat al vitamin C and E supplementation in smokers is associated with reduced placental abruption and preterm birth: a secondary analysis[J ] . BJOG, 2015, 122(13): 1740-1747. DOI: 10.1111/1471-0528.13201.
QIU C, GELAYE B, DENIS M, et al . Circadian clock-related genetic risk scores and risk of placental abruption[J ] . Placenta, 2015, 36(12): 1480-1486. DOI: 10.1016/j.placenta.2015.10.005.
HUANG Q T, CHEN J H, ZHONG M, et al . The risk of placental abruption and placenta previa in pregnant women with chronic hepatitis B viral infection: a systematic review and meta-analysis[J ] . Placenta, 2014, 35(8): 539-545. DOI: 10.1016/j.placenta.2014.05.007.
WOOD A. Second trimester hyperemesis gravidarum is associated with increased risk of preterm pre-eclampsia, placental abruption and small for gestational age birth[J]. Evid Based Nurs, 2014, 17(3): 74. DOI: 10.1136/eb-2013-101423.
IGWEGBE A O, ELEJE G U, OKPALA B C. Management outcomes ofabruptio placentae at Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria[J]. Niger J Med, 2013, 22(3): 234-238.
TAKEDA A, IMOTO S, NAKAMURA H. Abruptio placentae in subsequent pregnancy after conservative management of hemorrhagic cesarean scar pregnancy by transcatheter arterial chemoembolization[J]. Clin Med Insights Case Rep, 2013, 6: 137-140. DOI: 10.4137/CCRep.S12744.
MASSELLI G, BRUNELLI R, D I TOLA M, et al . MR imaging in the evaluation of placental abruption: correlation with sonographic findings[J ] . Radiology, 2011, 259(1): 222-230. DOI: 10.1148/radiol.10101547.
ANANTH C V, OYELESE Y, YEO L, et al . Placental abruption in the United States, 1979 through 2001: temporal trends and potential determinants[J ] . Am J Obstet Gynecol, 2005, 192(1): 191-198. DOI: 10.1016/j.ajog.2004.05.087.
WALLIA A, BIZHANOVA A, HUANG W, et al . Acute diabetes insipidus mediated by vasopressinase after placental abruption[J ] . J Clin Endocrinol Metab, 2013, 98(3): 881-886. DOI:10.1210/jc.2012-3548.
RIIHIMÄKI O, METSÄRANTA M, RITVANEN A, et al . Increased prevalence of major congenital anomalies in births with placental abruption[J ] . Obstet Gynecol, 2013, 122(2 Pt 1): 268-274. DOI: 10.1097/AOG. 0b013e31829a6f91.
MASSELLI G, DE RCHI L, MCHUGO J, et al . Acute abdominal and pelvic pain in pregnancy: ESUR recommendations[J ] . Eur Radiol, 2013, 23(12): 3485-3500. DOI: 10.1007/s00330-013-2987-7.
BREATHNACH F M, DONNELLY J, COOLEY S M, et al . Subclinical hypothyroidism as a risk factor for placental abruption: evidence from a low-risk primigravid population[J ] . Aust N Z J Obstet Gynaecol, 2013, 53(6): 553-560. DOI: 10.1111/ajo.12131.
BERHAN Y. Predictors of perinatal mortality associated with placenta previa and placental abruption: an experience from a low income country[J]. J Pregnancy, 2014, 2014: 307043. DOI: 10.1155/2014/307043.
0
浏览量
0
下载量
0
CSCD
关联资源
相关文章
相关作者
相关机构
京公网安备11010802024621