经胸超声心动图结合右心声学造影在判断卵圆孔未闭右向左分流中的临床价值

王文婷; 黄海韵; 柳强维; 姚青; 宋治远; 郭燕丽

doi:10.16016/j.1000-5404.201704145

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经胸超声心动图结合右心声学造影在判断卵圆孔未闭右向左分流中的临床价值

临床医学 | 更新时间：2026-01-09

- 经胸超声心动图结合右心声学造影在判断卵圆孔未闭右向左分流中的临床价值
- Clinical values of transthoracic echocardiography combined with right heart contrast echocardiography in the right-to-left shunt of patent foramen ovale
- 第三军医大学学报 2017年39卷第16期页码：1648-1653
- 作者机构：
- 作者简介：
- 基金信息：
  
  重庆市社会民生科技创新专项项目(CSTC2016shmszx130080);第三军医大学西南医院临床创新基金(SWH2013LC17)
- DOI：10.16016/j.1000-5404.201704145
  中图分类号：
- 收稿：2017-04-27，
  
  纸质出版：2017-08-30
- 稿件说明：
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王文婷, 黄海韵, 柳强维, 等. 经胸超声心动图结合右心声学造影在判断卵圆孔未闭右向左分流中的临床价值[J]. 第三军医大学学报, 2017,39(16):1648-1653.

Wenting WANG, Haiyun HUANG, Qiangwei LIU, et al. Clinical values of transthoracic echocardiography combined with right heart contrast echocardiography in the right-to-left shunt of patent foramen ovale[J]. Journal of Third Military Medical University, 2017, 39(16): 1648-1653.
王文婷, 黄海韵, 柳强维, 等. 经胸超声心动图结合右心声学造影在判断卵圆孔未闭右向左分流中的临床价值[J]. 第三军医大学学报, 2017,39(16):1648-1653. DOI： 10.16016/j.1000-5404.201704145.

Wenting WANG, Haiyun HUANG, Qiangwei LIU, et al. Clinical values of transthoracic echocardiography combined with right heart contrast echocardiography in the right-to-left shunt of patent foramen ovale[J]. Journal of Third Military Medical University, 2017, 39(16): 1648-1653. DOI： 10.16016/j.1000-5404.201704145.

摘要

Abstract

Objective

To explore the clinical values of transthoracic echocardiography (TTE) combined with right heart contrast echocardiography in the diagnosis of patent foramen ovale (PFO) and to assess the efficacy of transcatheter closure in PFO.

Methods

Three hundred and seventy-three patients

including 121 cases with unexplained stroke and 252 cases with migraine

who admitted in the cardiological and neurological departments of our hospital from January 2013 to December 2016

and needed to further diagnose in the presence or absence of PFO

were recruited in this study. All patients underwent TTE and right heart contrast echocardiography

and 103 of them underwent transesophageal echocardiography (TEE) voluntarily.

Results

① In the resting state

TTE in 373 patients showed 22 cases with PFO. Next

103 cases of 351 patients with no PFO detected by TTE received TEE

and the results showed 49 patients with PFO. ② All patients also underwent right heart contrast echocardiography when examined with TTE. The results showed that 186 of 373 cases (49.87%) had varying degrees of right-to-left shunt under the condition of Valsalva maneuver or severe cough [69 cases with mild right-to-left shunt (gradeⅠ)

70 cases with moderate shunt(grade Ⅱ) and 47 cases with severe shunt(grade Ⅲ)]. ③ And the examination also showed moderate or severe right-to-left shunts in both 22 cases with PFO confirmed by TTE and 49 cases with PFO confirmed by TEE. ④ Finally

59 patients

having moderate or severe right-to-left shunts confirmed by TTE combined with right heart contrast echocardiography and focal cerebral infarction by MRI

underwent TTE-guided percutaneous transcatheter closure. Right heart contrast echocardiography after 1-month closure operation showed that 55 cases had no right-to-left shunts and 4 cases had mild shunts (grade Ⅰ) under the condition of Valsalva maneuver or severe cough.

Conclusion

The combination of TTE and right heart contrast echocardiography could not only show the extent of right-to-left shunt in PFO clearly and provide direct basis for PFO clinical treatment

but also be an effective follow-up method after PFO transcatheter closure. It has been an important tool in PFO diagnosis and follow-up examination after transcatheter closure.

关键词

Keywords

references

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