胰十二指肠切除术后胰瘘的高危因素及胰体部平扫CT值对其预测价值的分析

杨美文; 邓永; 黄涛; 张雷达

doi:10.16016/j.1000-5404.201702081

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胰十二指肠切除术后胰瘘的高危因素及胰体部平扫CT值对其预测价值的分析

临床医学 | 更新时间：2026-01-09

- 胰十二指肠切除术后胰瘘的高危因素及胰体部平扫CT值对其预测价值的分析
- High risk factors for pancreatic fistula after pancreaticoduodenectomy and predictive value of plain CT scanning in pancreatic body
- 第三军医大学学报 2017年39卷第11期页码：1177-1182
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.16016/j.1000-5404.201702081
  中图分类号：
- 收稿：2017-02-17，
  
  纸质出版：2017-06-15
- 稿件说明：
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杨美文, 邓永, 黄涛, 等. 胰十二指肠切除术后胰瘘的高危因素及胰体部平扫CT值对其预测价值的分析[J]. 第三军医大学学报, 2017,39(11):1177-1182.

Meiwen Yang, Yong Deng, Tao Huang, et al. High risk factors for pancreatic fistula after pancreaticoduodenectomy and predictive value of plain CT scanning in pancreatic body[J]. Journal of Third Military Medical University, 2017, 39(11): 1177-1182.
杨美文, 邓永, 黄涛, 等. 胰十二指肠切除术后胰瘘的高危因素及胰体部平扫CT值对其预测价值的分析[J]. 第三军医大学学报, 2017,39(11):1177-1182. DOI： 10.16016/j.1000-5404.201702081.

Meiwen Yang, Yong Deng, Tao Huang, et al. High risk factors for pancreatic fistula after pancreaticoduodenectomy and predictive value of plain CT scanning in pancreatic body[J]. Journal of Third Military Medical University, 2017, 39(11): 1177-1182. DOI： 10.16016/j.1000-5404.201702081.

摘要

Abstract

Objective

To investigate the high risk factors for pancreatic fistula after pancreaticoduodenectomy (PD) and the predictive value of plain CT scanning of the body of the pancreas.

Methods

Whole clinical data of 408 patients undergoing PD in our institute from January 2013 to December 2015 were collected and retrospectively analyzed. Univariate analysis using Pearson

Chi

-square test

multivariate analysis using binary logistic regression analysis

and simple linear correlation analysis were used to analyze the correlation between the values of CT scanning and pancreatic fistula. The predictive value of the CT values for pancreatic fistula after PD was analyzed by the receiver operating characteristic (ROC) curve.

Results

There were 123 cases (30.14%) of postoperative pancreatic fistula in 408 patients. Univariate analysis showed that body mass index (BMI)

preoperative gamma glutamyl transpeptidase

diameter of pancreatic duct

plain scanning CT values of pancreatic body

operation time

and texture of pancreas (judged intraoperatively) were risk factors for pancreatic fistula after PD. Multivariate analysis showed that BMI≥25 kg/m

pancreatic duct diameter ≤3 mm

CT value of pancreatic body

40 Hu

and soft texture were independent high risk factors for pancreatic fistula after PD. There were significant differences in CT values o

f pancreatic body in The patients with different severity of pancreatic fistula (

0.05). The severity was negatively correlated with the CT value of pancreatic body. The area under ROC for the CT value of pancreatic body was 0.714

indicating a moderate predictive value for pancreatic fistula after PD.

Conclusion

BMI≥25 kg/m

pancreatic duct diameter ≤3 mm

plain scanning CT value of pancreatic body

40 Hu

intraoperative soft texture of pancreas are independent high risk factors for pancreatic fistula after PD. The CT value is of moderate predictive value for the fistula

and can used to guide the perioperative treatment regimen.

关键词

Keywords

references

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