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收稿:2017-01-10,
纸质出版:2017-06-15
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许磊, 王婷, 陈亭, 等. 重症患者肠内营养喂养不耐受临床常用措施效果分析[J]. 第三军医大学学报, 2017,39(11):1171-1176.
Lei Xu, Ting Wang, Ting Chen, et al. Efficacy of medical and nursing measures for enteral nutrition intolerance in critically ill patients[J]. Journal of Third Military Medical University, 2017, 39(11): 1171-1176.
许磊, 王婷, 陈亭, 等. 重症患者肠内营养喂养不耐受临床常用措施效果分析[J]. 第三军医大学学报, 2017,39(11):1171-1176. DOI: 10.16016/j.1000-5404.201701057.
Lei Xu, Ting Wang, Ting Chen, et al. Efficacy of medical and nursing measures for enteral nutrition intolerance in critically ill patients[J]. Journal of Third Military Medical University, 2017, 39(11): 1171-1176. DOI: 10.16016/j.1000-5404.201701057.
Objective
2
To observe and analyze the effect of clinical common medical and nursing measures on enteral nutrition intolerance in critically ill patients.
Methods
2
Clinical data of 160 critically ill patients hospitalized in ICU of Daping Hospital from March to October 2016 were collected and analyzed. Eventually 109 patients meeting our inclusion criteria were included. The patients divided into 2 groups according to the types of nutrient solution
whether they early used catharsis
enema and prokinetic drugs (at th
e beginning of enteral feeding)
and whether supplement of albumin
probiotics
mixed glutamine innutrient solution
and in combination of parenteral nutrition. Univariate analysis was used
and those with
P
<
0.1 in the univariate analysis were evaluated by multivariate logistic regression analysis.
Results
2
Univariate analysis showed that type of nutrient solution
early use of catharsis
early use of enema
early use of prokinetic drugs
and supplement of album reduced the effect of enteral nutrition intolerance significantly (
P
<
0.05). Multivariate logistic regression analysis indicated that type of nutrient solution (
OR
=0.152
P
=0.001
95%
CI
: 0.052~0.446)
early use of prokinetic drugs (
OR
=0.197
P
=0.015
95%
CI
: 0.054~0.726)
early use of enema (
OR
=0.251
P
=0.010
95%
CI
: 0.088~0.718) were the main independent protective factors to reduce incidence of feeding intolerance.
Conclusion
2
At the beginning of enteral nutrition intolerance for critically ill patients
choosing whole protein of nutrient solution (except pancreatitis patients) and early use of prokinetic drugs and enema can effectively reduce the occurrence of feeding intolerance.
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