糖尿病酮症酸中毒住院患者的预后因素分析

张春林; 刘刚; 童强; 张瑞

doi:10.16016/j.1000-5404.201701038

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糖尿病酮症酸中毒住院患者的预后因素分析

临床医学 | 更新时间：2026-01-09

- 糖尿病酮症酸中毒住院患者的预后因素分析
- Prognostic factors in hospitalized patients with diabetic ketoacidosis
- 第三军医大学学报 2017年39卷第16期页码：1659-1663
- 作者机构：
- 作者简介：
- 基金信息：
  
  国家自然基金青年科学基金项目(81401601)
- DOI：10.16016/j.1000-5404.201701038
  中图分类号：
- 收稿：2017-01-05，
  
  纸质出版：2017-08-30
- 稿件说明：
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张春林, 刘刚, 童强, 等. 糖尿病酮症酸中毒住院患者的预后因素分析[J]. 第三军医大学学报, 2017,39(16):1659-1663.

Chunlin ZHANG, Gang LIU, Qiang TONG, et al. Prognostic factors in hospitalized patients with diabetic ketoacidosis[J]. Journal of Third Military Medical University, 2017, 39(16): 1659-1663.
张春林, 刘刚, 童强, 等. 糖尿病酮症酸中毒住院患者的预后因素分析[J]. 第三军医大学学报, 2017,39(16):1659-1663. DOI： 10.16016/j.1000-5404.201701038.

Chunlin ZHANG, Gang LIU, Qiang TONG, et al. Prognostic factors in hospitalized patients with diabetic ketoacidosis[J]. Journal of Third Military Medical University, 2017, 39(16): 1659-1663. DOI： 10.16016/j.1000-5404.201701038.

摘要

Abstract

Objective

To retrospectively analyze the prognostic factors for diabetic ketoacidsis (DKA) in order to improve the diagnosis and treatment and decreased the mortality for DKA.

Methods

Clinical data of all DKA patients admitted in our department of endocrinology from January 2014 to December 2016 were collected and retrospectively analyzed. The patients were divided into the survival group and dead group. The baseline data

blood routine results

liver and renal functions

electrolyte levels

C-reactive protein (CRP) level

Scores of Glasgow coma scale (GCS) and acute physiology and chronic health evaluation Ⅱ (APACHEⅡ)

and prognosis of the DKA patients were analyzed.

Results

There were totally 70 subjects enrolled

including 36

males and 34 females

at an average age of 42.63±15.67 years. When compared with the dead group

the survival group had significantly higher GCS score (14.41±1.42

11.36±3.14) and serum phosphate (0.96±0.47

0.68±0.60 mg/L)

but obviously lower APACHEⅡ score (8.58±4.63

15.73±4.38)

white blood cells count [(22.80±7.67)×10

(14.82±9.55)×10

]

CRP level (211.39±173.93

33.67±45.70 mg/L)

serum creatinine (136.47±87.50

87.28±43.89 μmol/L)

and urea nitrogen (14.72±9.23

8.45±5.00 mmol/L)(all

0.05

0.01). The lower the GCS score was (

=0.510

0.05) and the higher APACHEⅡ score (

=1.300

0.05) and CRP level (

=1.031

0.05) were

the worse the prognosis was in the DKA patients.

Conclusion

CRP level

GCS score and APACHEⅡ score are independent prognostic factors for DKA patients.

关键词

Keywords

references

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