980 nm连续激光在金属医疗器械表面高效灭菌的实验研究

程和平; 曾梁楠; 黄智蒙; 陈琰琰; 陈图南; 冯华; 鲜继淑

doi:10.16016/j.1000-5404.201611255

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980 nm连续激光在金属医疗器械表面高效灭菌的实验研究

基础医学 | 更新时间：2026-01-09

- 980 nm连续激光在金属医疗器械表面高效灭菌的实验研究
- Sterilizing effect of 980 nm continuous laser on metal surface of medical equipment
- 第三军医大学学报 2017年39卷第9期页码：878-883
- 作者机构：
- 作者简介：
- 基金信息：
  
  中国博士后科学基金(2014M552542XB);中国博士后科学基金(2015T80989);国家自然科学基金面上项目(81402067);黄山学院人才启动项目(2016xkjq001);中国工程物理研究院基金(JM20150);中国工程物理研究院物理与生物医学交叉实验室孵化基金(JCFH)
- DOI：10.16016/j.1000-5404.201611255
  中图分类号：
- 收稿：2016-11-30，
  
  纸质出版：2017-05-15
- 稿件说明：
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程和平, 曾梁楠, 黄智蒙, 等. 980 nm连续激光在金属医疗器械表面高效灭菌的实验研究[J]. 第三军医大学学报, 2017,39(9):878-883.

Heping Cheng, Liangnan Zeng, Zhimeng Huang, et al. Sterilizing effect of 980 nm continuous laser on metal surface of medical equipment[J]. Journal of Third Military Medical University, 2017, 39(9): 878-883.
程和平, 曾梁楠, 黄智蒙, 等. 980 nm连续激光在金属医疗器械表面高效灭菌的实验研究[J]. 第三军医大学学报, 2017,39(9):878-883. DOI： 10.16016/j.1000-5404.201611255.

Heping Cheng, Liangnan Zeng, Zhimeng Huang, et al. Sterilizing effect of 980 nm continuous laser on metal surface of medical equipment[J]. Journal of Third Military Medical University, 2017, 39(9): 878-883. DOI： 10.16016/j.1000-5404.201611255.

摘要

Abstract

Objective

To investigate the relationship of power and exposure period of 980 nm continuous laser system on the surface sterilization for metal medical equipment.

Methods

The sterile steel lancets were artificially contaminated with

Staphylococcus aureus

and

Escherichia coli

respectively. These lancets were exposed and disinfected by 980 nm continuous laser at different powers for different time periods. The inactivation of the bacteria on each lancet was observed and measured by 8-hour enrichment culture.

Results

Staphylococcus aureus

were thoroughly killed after the lancets were disinfected by the 980 nm laser at 5.24 W for 29 s

6.87 W for 24 s

8.33 W for 14 s

and 10.11 W for 14 s

respectively. The power and exposure period for

Escherichia coli

were 5.24 W for 22 s

6.87 W for 12 s

8.33 W for 11 s

and 10.11 W for 9 s

respectively.

Escherichia coli

was more likely to be inactivated than

Staphylococcus aureus

. According to the experimental data

the survival rate under same power of infrared laser as a function of irradiation time was fitted to the first-order kinetics equation.

Conclusion

980 nm infrared laser can achieve rapid sterilization on metal surface of medical equipment in a very short time period. The larger power the laser is with

the shorter is the exposure period

and the better the sterilizing effect is.

关键词

Keywords

references

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