西青果丙酮及水提取物体外抗氧化活性初步研究

赵鸿燕; 刘芳; 谢永红; 戴青; 刘松青

doi:10.16016/j.1000-5404.201611126

您当前的位置：

首页 >

文章列表页 >

西青果丙酮及水提取物体外抗氧化活性初步研究

基础医学 | 更新时间：2026-01-09

- 西青果丙酮及水提取物体外抗氧化活性初步研究
- Antioxidant activities of acetone and aqueous extracts from Terminalia chebula Retz. in vitro
- 第三军医大学学报 2017年39卷第9期页码：891-896
- 作者机构：
- 作者简介：
- 基金信息：
  
  重庆市应用开发项目(CSTC2014yykfA110023)
- DOI：10.16016/j.1000-5404.201611126
  中图分类号：
- 收稿：2016-11-14，
  
  纸质出版：2017-05-15
- 稿件说明：
移动端阅览
赵鸿燕, 刘芳, 谢永红, 等. 西青果丙酮及水提取物体外抗氧化活性初步研究[J]. 第三军医大学学报, 2017,39(9):891-896.

Hongyan Zhao, Fang Liu, Yonghong Xie, et al. Antioxidant activities of acetone and aqueous extracts from Terminalia chebula Retz. in vitro[J]. Journal of Third Military Medical University, 2017, 39(9): 891-896.
赵鸿燕, 刘芳, 谢永红, 等. 西青果丙酮及水提取物体外抗氧化活性初步研究[J]. 第三军医大学学报, 2017,39(9):891-896. DOI： 10.16016/j.1000-5404.201611126.

Hongyan Zhao, Fang Liu, Yonghong Xie, et al. Antioxidant activities of acetone and aqueous extracts from Terminalia chebula Retz. in vitro[J]. Journal of Third Military Medical University, 2017, 39(9): 891-896. DOI： 10.16016/j.1000-5404.201611126.

摘要

Abstract

Objective

To investigate

in vitro

antioxidant activities of acetone and aqueous extracts from

Terminalia chebula Retz.

by 3 evaluation systems.

Methods

Total phenolic contents of the acetone extract and aqueous extract from

Terminalia chebula Retz.

were determined by Folin-Ciocalteu reagent. Using 2

2-diphenyl-1-picrylhydrazyl (DPPH·) and 2

2-azinobis-(3-ethylbenzothiazolin-6-sulfonic acid) diammonium salt (ABTS+·) radical scavenging assay and reducing power to evaluate the

in vitro

antioxidant activities of the acetone extract and aqueous extract from

Terminalia chebula Retz.

Results

The total phenolic content was 622.19±1.35 and 457.43±0.96 mg/g

respectively. The acetone extract and aqueous extract showed strong antioxidant activity. In the experiment of DPPH radical scavenging assay

the IC

values of the acetone extract and aqueous extract from

Terminalia chebula Retz.

were 8.427 and 19.575 μg/mL respectively. ABTS radical scavenging assay showed their IC

values were 20.273 and 33.064 μg/mL

respectively. All of the extracts had deoxidization ability of Fe

and the

Results

showed a good dose-concentration relationship. Acetone extract showed strong reduction power.

Conclusion

The acetone extract and aqueous extract of

Terminalia chebula Retz.

exhibit better

in vitro

antioxidant capacity.

关键词

Keywords

references

国家药典委员会中国药典2015版 (一部) 北京中国医药科技出版社 2015 130 国家药典委员会.中国药典2015版 (一部)[M].北京:中国医药科技出版社, 2015:130.

Chinese Pharmacopoeia Commission Pharmacopoeia of the People's Republic of China (volume one) Beijing China Medical Science Press Publishing 2015 130 Chinese Pharmacopoeia Commission. Pharmacopoeia of the People's Republic of China (volume one)[M].Beijing:China Medical Science Press Publishing, 2015: 130.

颜玉贞卢平华谢培山西青果与诃子的HPLC指纹图谱鉴别研究中药新药与临床药理 2001 12 3 173 178 10.3321/j.issn:1003-9783.2001.03.007 颜玉贞, 卢平华, 谢培山.西青果与诃子的HPLC指纹图谱鉴别研究[J].中药新药与临床药理, 2001, 12(3): 173-178.DOI:10.3321/j.issn:1003-9783.2001.03.007.

Yan Y Z Lu P H Xie P S Study on Chromatographic Fingerprint of Immature Fruits of Terminalia (Xi Qing Guo) and the Fruits of Terminalia spp.(He Zi) Traditional Chinese Drug Research and Clinical Pharmacology 2001 12 3 173 178 10.3321/j.issn:1003-9783.2001.03.007 Yan Y Z, Lu P H, Xie P S. Study on Chromatographic Fingerprint of Immature Fruits of Terminalia (Xi Qing Guo) and the Fruits of Terminalia spp.(He Zi)[J]. Traditional Chinese Drug Research and Clinical Pharmacology, 2001, 12(3):173-178.DOI:10.3321/j.issn:1003-9783.2001.03.007.

刘芳秦红飞刘松青诃子化学成分与药理活性研究进展中国药房 2012 23 7 670 672 10.6039/j.issn.1001-0408.2012.07.35 刘芳, 秦红飞, 刘松青.诃子化学成分与药理活性研究进展[J].中国药房, 2012, 23(7):670-672.DOI:10.6039/j.issn.1001-0408.2012.07.35.

Liu F Qin H F Liu S Q Chemical constituents and pharmacological development of Terminalia chebula Retz China Pharmacy 2012 23 7 670 672 10.6039/j.issn.1001-0408.2012.07.35 Liu F, Qin H F, Liu S Q. Chemical constituents and pharmacological development of Terminalia chebula Retz [J ] . China Pharmacy, 2012, 23(7): 670-672. DOI: 10.6039/j.issn.1001-0408.2012.07.35.

Zhao Y Liu F Liu Y Anti-Arthritic Effect of Chebulanin on Collagen-Induced Arthritis in Mice PLoS One 2015 10 9 e0139052 10.1371/journal.pone.0139052 Zhao Y, Liu F, Liu Y, et al. Anti-Arthritic Effect of Chebulanin on Collagen-Induced Arthritis in Mice[J]. PLoS One, 2015, 10(9):e0139052.DOI:10.1371/journal.pone. 0139052.

Kusirisin W Srichairatanakool S Lerttrakarnnon P Antioxidative activity, polyphenolic content and anti-glycation effect of some Thai medicinal plants traditionally used in diabetic patients Med Chem 2009 5 2 139 147 10.2174/157340609787582918 Kusirisin W, Srichairatanakool S, Lerttrakarnnon P, et al. Antioxidative activity, polyphenolic content and anti-glycation effect of some Thai medicinal plants traditionally used in diabetic patients[J]. Med Chem, 2009, 5(2): 139-147.

Sarkar R Hazra B Mandal N Reducing power and iron chelating property of Terminalia chebula ( Retz .) alleviates iron induced liver toxicity in mice BMC Complement Altern Med 2012 12 144 10.1186/1472-6882-12-144 Sarkar R, Hazra B, Mandal N. Reducing power and iron chelating property of Terminalia chebula ( Retz .) alleviates iron induced liver toxicity in mice[J ] . BMC Complement Altern Med, 2012, 12: 144.DOI:10.1186/1472-6882-12-144.

Salimikia I Monsef-Esfahani H R Gohari A R Phytochemical Analysis and Antioxidant Activity of Salvia chloroleuca Aerial Extracts Iran Red Crescent Med J 2016 18 8 e24836 10.5812/ircmj.24836 Salimikia I, Monsef-Esfahani H R, Gohari A R, et al. Phytochemical Analysis and Antioxidant Activity of Salvia chloroleuca Aerial Extracts[J]. Iran Red Crescent Med J, 2016, 18(8): e24836. DOI:10.5812/ircmj.24836.

蔡恩博杨利民梁彩霞小叶丁香枝不同部位抗氧化活性研究人参研究 2015 27 2 28 32 10.3969/j.issn.1671-1521.2015.02.010 蔡恩博, 杨利民, 梁彩霞, 等.小叶丁香枝不同部位抗氧化活性研究[J].人参研究, 2015, 27(2): 28-32.DOI:10.3969/j.issn.1671-1521.2015.02.010.

Cai E B Yang L M Liang C X Study on Antioxidative Properties of Different Fractions from the branch of Syringa pubescens Turcz Ginseng Res 2015 27 2 28 32 10.3969/j.issn.1671-1521.2015.02.010 Cai E B, Yang L M, Liang C X, et al. Study on Antioxidative Properties of Different Fractions from the branch of Syringa pubescens Turcz[J]. Ginseng Res, 2015, 27(2): 28-32.DOI:10.3969/j.issn.1671-1521.2015.02.010.

Liu J Li X Lin J Sarcandra glabra (Caoshanhu) protects mesenchymal stem cells from oxidative stress: a bioevaluation and mechanistic chemistry BMC Complement Altern Med 2016 16 423 10.1186/s12906-016-1383-7 Liu J, Li X, Lin J, et al. Sarcandra glabra (Caoshanhu) protects mesenchymal stem cells from oxidative stress: a bioevaluation and mechanistic chemistry[J]. BMC Complement Altern Med, 2016, 16: 423. DOI:10.1186/s12906-016-1383-7.

蔡恩博郭雪赵岩牛蒡子75%乙醇提取物总酚含量及抗氧化活性研究人参研究 2015 27 1 19 23 10.3969/j.issn.1671-1521.2015.01.006 蔡恩博, 郭雪, 赵岩, 等.牛蒡子75%乙醇提取物总酚含量及抗氧化活性研究[J].人参研究, 2015, 27(1): 19-23.DOI: 10.3969/j.issn.1671-1521.2015.01.006.

Cai E B Guo X Zhao Y The study of total phenolics content and antioxidant activities of 75% ethanol extracts from Arctium lappa L Ginseng Res 2015 27 1 19 23 10.3969/j.issn.1671-1521.2015.01.006 Cai E B, Guo X, Zhao Y, et al. The study of total phenolics content and antioxidant activities of 75% ethanol extracts from Arctium lappa L [J ] . Ginseng Res, 2015, 27(1):19-23.DOI: 10.3969/j.issn.1671-1521.2015.01. 006.

Arulselvan P Fard M T Tan W S Role of Antioxidants and Natural Products in Inflammation Oxid Med Cell Longev 2016 2016 5276130 10.1155/2016/5276130 Arulselvan P, Fard M T, Tan W S, et al. Role of Antioxidants and Natural Products in Inflammation[J]. Oxid Med Cell Longev, 2016, 2016: 5276130. DOI:10.1155/2016/5276130.

Gupta V K Sharma S K Plants as natural antioxidants Nat Prod Rad 2014 5 4 326 334 http://nopr.niscair.res.in/handle/123456789/7962 Gupta V K, Sharma S K. Plants as natural antioxidants[J]. Nat Prod Rad, 2014, 5(4): 326-334.

Zhang Y Wang X Wang Y Supplementation of cyanidin-3-O-β-glucoside promotes endothelial repair and prevents enhanced atherogenesis in diabetic apolipoprotein E-deficient mice J Nutr 2013 143 8 1248 1253 10.3945/jn.113.177451 Zhang Y, Wang X, Wang Y, et al. Supplementation of cyanidin-3-O-β-glucoside promotes endothelial repair and prevents enhanced atherogenesis in diabetic apolipoprotein E-deficient mice[J]. J Nutr, 2013, 143(8): 1248-1253. DOI:10.3945/jn.113.177451.

Zhu X Hu S Zhu L Effects of Lycium barbarum polysaccharides on oxidative stress in hyperlipidemic mice following chronic composite psychological stress intervention Mol Med Rep 2015 11 5 3445 3450 10.3892/mmr.2014.3128 Zhu X, Hu S, Zhu L, et al. Effects of Lycium barbarum polysaccharides on oxidative stress in hyperlipidemic mice following chronic composite psychological stress intervention[J]. Mol Med Rep, 2015, 11(5): 3445-3450. DOI:10.3892/mmr.2014.3128.

Wang B F Lin S Bai M H Effects of SSd Combined with Radiation on Inhibiting SMMC-7721 Hepatoma Cell Growth Med Sci Monit 2014 20 1340 1344 10.12659/MSM.891355 Wang B F, Lin S, Bai M H, et al. Effects of SSd Combined with Radiation on Inhibiting SMMC-7721 Hepatoma Cell Growth[J]. Med Sci Monit, 2014, 20: 1340-1344.DOI:10.12659/MSM.891355.

刘志东郭本恒王荫榆抗氧化活性检测方法的研究进展天然产物研究与开发 2008 20 3 563 567 10.3969/j.issn.1001-6880.2008.03.045 刘志东, 郭本恒, 王荫榆.抗氧化活性检测方法的研究进展[J].天然产物研究与开发, 2008, 20(3): 563-567.DOI: 10.3969/j.issn.1001-6880.2008.03.045.

Liu Z D Guo B H Wang Y Y Methods to Determine Antioxidative Activity Nat Prod Res Dev 2008 20 3 563 567 10.3969/j.issn.1001-6880.2008.03.045 Liu Z D, Guo B H, Wang Y Y. Methods to Determine Antioxidative Activity[J]. Nat Prod Res Dev, 2008, 20(3): 563-567.DOI: 10.3969/j.issn.1001-6880.2008.03.045.

Li J E Cui S W Nie S P Structure and biological activities of a pectic polysaccharide from Mosla chinensis Maxim. cv. Jiangxiangru Carbohydr Polym 2014 105 276 284 10.1016/j.carbpol.2014.01.081 Li J E, Cui S W, Nie S P, et al. Structure and biological activities of a pectic polysaccharide from Mosla chinensis Maxim. cv. Jiangxiangru[J]. Carbohydr Polym, 2014, 105: 276-284.DOI:10.1016/j.carbpol.2014.01.081.

邝春林吕都黄霞杭白菊不同溶剂提取物的抗氧化活性研究食品工业科技 2015 36 21 83 87 10.13386/j.issn1002-0306.2015.21.008 邝春林, 吕都, 黄霞, 等.杭白菊不同溶剂提取物的抗氧化活性研究[J].食品工业科技, 2015, 36(21): 83-87.DOI:10.13386/j.issn1002-0306.2015.21.008.

Kuang C L Lyu D Huang X Research of the antioxidant activity of Chrysanthemum Morifolium's extracts with different solvents Sci Tech Food Ind 2015 36 21 83 87 10.13386/j.issn1002-0306.2015.21.008 Kuang C L, Lyu D, Huang X, et al. Research of the antioxidant activity of Chrysanthemum Morifolium's extracts with different solvents[J]. Sci Tech Food Ind, 2015, 36(21): 83-87.DOI:10.13386/j.issn1002-0306.2015.21.008.

涂宗财傅志丰王辉红薯叶不同溶剂提取物抗氧化性及活性成分鉴定食品科学 2015 36 17 1 6 10.7506/spkx1002-6630-201517001 涂宗财, 傅志丰, 王辉, 等.红薯叶不同溶剂提取物抗氧化性及活性成分鉴定[J].食品科学, 2015, 36(17): 1-6. DOI:10.7506/spkx1002-6630-201517001.

Tu Z C Fu Z F Wang H Comparison of Antioxidant activities of various solvent extracts of sweet potato ( Ipomoea batatas (L.) Lam. ) leaves and identification of antioxidant constituents of the merthanol extract Food Sci 2015 36 17 1 6 10.7506/spkx1002-6630-201517001 Tu Z C, Fu Z F, Wang H, et al. Comparison of Antioxidant activities of various solvent extracts of sweet potato ( Ipomoea batatas (L.) Lam. ) leaves and identification of antioxidant constituents of the merthanol extract[J ] . Food Sci, 2015, 36(17): 1-6. DOI:10.7506/spkx1002-6630-201517001.

Rangsriwong P Rangkadilok N Satayavivad J Subcritical water extraction of polyphenolic compounds from Terminalia chebula Retz. fruits Separation & Purification Technology 2009 66 1 51 56 10.1016/j.seppur.2008.11.023 Rangsriwong P, Rangkadilok N, Satayavivad J, et al. Subcritical water extraction of polyphenolic compounds from Terminalia chebula Retz. fruits[J ] . Separation & Purification Technology, 2009, 66(1): 51-56. DOI:10.1016/j.seppur. 2008.11.023.

Manosroi A Jantrawut P Akazawa H Biological activities of phenolic compounds isolated from galls of Terminalia chebula Retz (Combretaceae) Nat Prod Res 2010 24 20 1915 1926 10.1080/14786419.2010.488631 Manosroi A, Jantrawut P, Akazawa H, et al. Biological activities of phenolic compounds isolated from galls of Terminalia chebula Retz (Combretaceae)[J ] . Nat Prod Res, 2010, 24(20): 1915-1926.DOI:10.1080/14786419.2010. 488631.

Chang C L Lin C S Phytochemical Composition, Antioxidant Activity, and Neuroprotective Effect of Terminalia chebula Retzius Extracts Evid Based Complement Alternat Med 2012 2012 125247 10.1155/2012/125247 Chang C L, Lin C S. Phytochemical Composition, Antioxidant Activity, and Neuroprotective Effect of Terminalia chebula Retzius Extracts[J ] . Evid Based Complement Alternat Med, 2012, 2012: 125247.DOI:10.1155/2012/125247.

浏览量

下载量

CSCD

文章被引用时，请邮件提醒。

提交

工具集

关联资源

暂无数据