锶纳米羟基磷灰石原花青素复合涂膜对牙本质小管的封闭作用

甄佳秀; 杨正艳; 左静; 周智

doi:10.16016/j.1000-5404.201611095

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锶纳米羟基磷灰石原花青素复合涂膜对牙本质小管的封闭作用

更新时间：2026-01-09

- 锶纳米羟基磷灰石原花青素复合涂膜对牙本质小管的封闭作用
- Sealing effect of procyanidins containing-strontium-substituted-hydroxyapatite composite varnish on dentinal tubules in vitro
- 第三军医大学学报 2017年39卷第7期页码：622-627
- 作者机构：
- 作者简介：
- 基金信息：
  
  重庆市卫生局医学科研计划重点项目(2013-1-032);重庆市中医药管理局项目(ZY20132111);重庆市渝北区科技项目(2014(社)-13号);重庆市卫生计生委医学科研项目(2015MSXM049);2016年重庆高校创新团队建设计划资助项目(CXTDG201602006)
- DOI：10.16016/j.1000-5404.201611095
  中图分类号：
- 收稿：2016-11-10，
  
  纸质出版：2017-07
- 稿件说明：
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甄佳秀, 杨正艳, 左静, 等. 锶纳米羟基磷灰石原花青素复合涂膜对牙本质小管的封闭作用[J]. 第三军医大学学报, 2017,39(7):622-627.

Jiaxiu Zhen, Zhengyan Yang, Jing Zuo, et al. Sealing effect of procyanidins containing-strontium-substituted-hydroxyapatite composite varnish on dentinal tubules in vitro[J]. Journal of Third Military Medical University, 2017, 39(7): 622-627.
甄佳秀, 杨正艳, 左静, 等. 锶纳米羟基磷灰石原花青素复合涂膜对牙本质小管的封闭作用[J]. 第三军医大学学报, 2017,39(7):622-627. DOI： 10.16016/j.1000-5404.201611095.

Jiaxiu Zhen, Zhengyan Yang, Jing Zuo, et al. Sealing effect of procyanidins containing-strontium-substituted-hydroxyapatite composite varnish on dentinal tubules in vitro[J]. Journal of Third Military Medical University, 2017, 39(7): 622-627. DOI： 10.16016/j.1000-5404.201611095.

摘要

Abstract

Objective

To investigate the occlusion effect of a novel nanoscaled procyanidins containing-strontium-substituted-hydroxyapatite varnish (SrHAP-PA) on the dentin tubules

in vitro

Methods

The model of dentin hypersensitivity was established in cow central incisors

then the sealing effect of SrHAP-PA varnish was examined on dentinal tubules under simulated human oral environment. Fluorine coating was used for the positive control group

and blank group served as negative control. Morphological alterations were observed by scanning electron microscopy (SEM). Energy dispersive X-ray microanalysis (EDX) were used to analyze the changes of element quality on dentin surface. Fourier transform infrared spectroscopy (FTIR) was carried out and confocal laser scanning microscopy was used to observe the dentin tubules.

Results

The dentin-hypersensitivity model was successfully constructed. The SrHAP-PA varnish was observed to effectively occlude the dentinal tubules by SEM. EDX showed that the SrHAP-PA composite film promoted remineralization and FTIR displayed that the SrHAP-PA varnish can quickly enter into the dentinal tubules

and save for a long time in the simulation of the oral environment.

Conclusion

The SrHAP-PA complex as the active ingredient of the coating material can effectively seal the dentinal tubules.

关键词

Keywords

references

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