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腹腔镜胆囊切除术后不同浓度罗哌卡因腹横肌平面阻滞镇痛效果的随机对照研究
Analgesic efficiency of different dose ropivacaine on transversus abdominis plane block after laparoscopic cholecystectomy: a randomized control trial
- 第三军医大学学报 2017年39卷第7期 页码：696-700
- 作者机构：
- 作者简介：
- 基金信息：
DOI：10.16016/j.1000-5404.201610114
中图分类号：收稿：2016-10-18，
纸质出版：2017-07
- 稿件说明：
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白洁, 孟玮, 黄生辉. 腹腔镜胆囊切除术后不同浓度罗哌卡因腹横肌平面阻滞镇痛效果的随机对照研究[J]. 第三军医大学学报, 2017,39(7):696-700.
Jie Bai, Wei Meng, Shenghui Huang. Analgesic efficiency of different dose ropivacaine on transversus abdominis plane block after laparoscopic cholecystectomy: a randomized control trial[J]. Journal of Third Military Medical University, 2017, 39(7): 696-700.
白洁, 孟玮, 黄生辉. 腹腔镜胆囊切除术后不同浓度罗哌卡因腹横肌平面阻滞镇痛效果的随机对照研究[J]. 第三军医大学学报, 2017,39(7):696-700. DOI： 10.16016/j.1000-5404.201610114.
Jie Bai, Wei Meng, Shenghui Huang. Analgesic efficiency of different dose ropivacaine on transversus abdominis plane block after laparoscopic cholecystectomy: a randomized control trial[J]. Journal of Third Military Medical University, 2017, 39(7): 696-700. DOI： 10.16016/j.1000-5404.201610114.
摘要
Abstract
Objective
2
To compare the analgestic efficacy on transversus abdominis plane (TAP) block
overall rehabilitation and relative adverse reactions of different doses of ropivacaine in patients after laparoscopic cholecystectomy (LC).
Methods
2
A total of 60 patients undergoing elective LC in our hospital from November 2015 to May 2016 were prospectively recruited in this study. They were randomly divided into 2 groups
and received 0.250% and 0.375% ropivacaine respectively for bilateral TAP block. Total intravenous anesthesia (TIVA) was adopted in all patients
and target controlled infusion (TCI) was carried out through the anesthetic induction and maintained intra-operatively. A skilled anesthesiologist performed the bilateral subcostal TAP block under ultrasound guidance before the surgical incision was made. After operation
all patients were given sulfentanil to maintain the pain relief. The patients complaining of pain
in the postanesthetic care unit and the surgical ward
were injected additional analgesic parocoxib and sulfentanil. Afterwards
the following results of all patients were recorded: the first time to receive the additional analgesic
total dose of opioids and parocoxib during the perioperative time
scores numeric rating scale (NRS) for pain at different intervals and relative adverse effects.
Results
2
Significant difference was found in the dose of remifentanil between the patients receiving different doses of ropivacaine in the bilateral TAP block (
P
<
0.05). But there were no differences in the total amounts of opioids and parocoxib
scores of NRS at different intervals and relative adverse effects between the 2 groups (
P
>
0.05).
Conclusion
2
Low dose ropivacaine exerts similar analgestic efficacy when compared with high dose
so it is recommended to improve its safety for TAP block.
关键词
Keywords
references
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